Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hsiang-Ling Kuo"'
Autor:
Yu-An Chen, Yong-Da Sie, Tsung-Yun Liu, Hsiang-Ling Kuo, Pei-Yi Chou, Yu-Jie Chen, Kuan-Ting Lee, Pin-Jun Chen, Shur-Tzu Chen, Nan-Shan Chang
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Yu-An Chen et al characterize the role of cell surface epitopes of the tumor suppressor protein WWOX in cell–cell recognition. The find that cells expressing functional WWOX, repel cancer cells which express dysfunctional WWOX or lack this protein,
Externí odkaz:
https://doaj.org/article/d4f330c1830c430db0064e8e0e79db70
Autor:
Li-Jin Hsu, Ming-Fu Chiang, Chun-I Sze, Wan-Pei Su, Ye Vone Yap, I-Ting Lee, Hsiang-Ling Kuo, Nan-Shan Chang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 4 (2016)
Hyaluronidase HYAL-2 is a membrane-anchored protein and also localizes, in part, in the lysosome. Recent study from animal models revealed that both HYAL-1 and HYAL-2 are essential for the metabolism of hyaluronan (HA). Hyal-2 deficiency is associate
Externí odkaz:
https://doaj.org/article/bd7d93a771c04d61bf73fdf89bc61fae
Autor:
Kuan Ting Lee, Shur Tzu Chen, Yong Da Sie, Yu-An Chen, Hsiang Ling Kuo, Nan-Shan Chang, Pei Yi Chou, Pin Jun Chen, Yu Jie Chen, Tsung Yun Liu
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Communications Biology
Communications Biology
Metastatic cancer cells are frequently deficient in WWOX protein or express dysfunctional WWOX (designated WWOXd). Here, we determined that functional WWOX-expressing (WWOXf) cells migrate collectively and expel the individually migrating WWOXd cells
Autor:
Chia Yun Wu, Nan-Shan Chang, Yu-An Chen, Li Jin Hsu, Kuang Yu Wen, Yong Da Sie, Chun I. Sze, Wan Pei Su, Pei Yi Chou, Tsung Yun Liu, Hsiang Ling Kuo, Feng Jie Lai
Publikováno v:
Cell Death Discovery, Vol 5, Iss 1, Pp 1-13 (2019)
Cell Death Discovery
Cell Death Discovery
Proapoptotic tumor suppressor WWOX is upregulated in the early stage of cancer initiation, which probably provides limitation to cancer growth and progression. Later, WWOX protein is reduced to enhance cancer cell growth, migration, invasiveness and
Autor:
Kuan‐Ting Lee, Tsung‐Yun Liu, Yu‐Jie Chen, Pei-Yi Chou, Yong-Da Sie, Yu-An Chen, Hsiang-Ling Kuo, Nan-Shan Chang
Publikováno v:
The FASEB Journal. 35
Autor:
Shenq Shyang Huang, Kuang Yu Wen, Ming Fu Chiang, Pei Chuan Ho, Tsung Yun Liu, Nan-Shan Chang, Yu-An Chen, Wan Pei Su, Chun I. Sze, Wan Jen Wang, Dudekula Subhan, Chia Yun Wu, Jean Yun Chang, Chen Yu Lu, Yu Jie Chen, Hsiang Ling Kuo, Ming Hui Lee, Sing Ru Lin
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2189, p 2189 (2020)
Cancers, vol 12, iss 8
Volume 12
Issue 8
Cancers, Vol 12, Iss 2189, p 2189 (2020)
Cancers, vol 12, iss 8
Synthetic Zfra4-10 and WWOX7-21 peptides strongly suppress cancer growth in vivo. Hypothetically, Zfra4-10 binds to the membrane Hyal-2 of spleen Z cells and activates the Hyal-2/WWOX/SMAD4 signaling for cytotoxic Z cell activation to kill cancer cel
Autor:
Dudekula Subhan, Sing Ru Lin, Chen Yu Lu, Ming Hui Lee, Jean Yun Chang, Pei Chuan Ho, Nan-Shan Chang, Ganesan Nagarajan, Wan Pei Su, Hsiang Ling Kuo, Katarina T. Chang, Wan Jen Wang, Yu-An Chen
Publikováno v:
Cancers, Vol 11, Iss 11, p 1818 (2019)
Cancers
Volume 11
Issue 11
Cancers
Volume 11
Issue 11
Membrane hyaluronidase Hyal-2 supports cancer cell growth. Inhibition of Hyal-2 by specific antibody against Hyal-2 or pY216-Hyal-2 leads to cancer growth suppression and prevention in vivo. By immunoelectron microscopy, tumor suppressor WWOX is show
Publikováno v:
The FASEB Journal. 34:1-1
Publikováno v:
Cell Death Discovery, Vol 4, Iss 1, Pp 1-9 (2018)
Cell Death Discovery
Cell death discovery, vol 4, iss 1
Cell Death Discovery
Cell death discovery, vol 4, iss 1
A feasible design is made to measure three protein/protein interactions to visualize signal pathways by time-lapse Förster resonance energy transfer (FRET) microscopy. When interacting proteins are in close proximity, excitation energy is provided t