Výsledky vyhledávání - "Hsiang Pu Feng"

Integrative Omics Analysis Reveals Soluble Cadherin-3 as a Survival Predictor and an Early Monitoring Marker of EGFR Tyrosine Kinase Inhibitor Therapy in Lung Cancer

Autor: Hao-Yu Lin, Jau-Song Yu, Chia-Jung Yu, Ko-Jiunn Liu, Ting-Feng Hsiao, Hsiang-Pu Feng, Gee-Chen Chang, Yi-Cheng Wu, Yen-Chuan Chiu, Kun-Yi Chien, Chih-Liang Wang

Publikováno v: Clinical Cancer Research. 26:3220-3229

Purpose: EGFR tyrosine kinase inhibitors (EGFR-TKI) benefit patients with advanced lung adenocarcinoma (ADC) harboring activating EGFR mutations. We aimed to identify biomarkers to monitor and predict the progression of patients receiving EGFR-TKIs v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7fbeb6022e2661884a96e46569c1f5
https://doi.org/10.1158/1078-0432.ccr-19-3972

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ArfGAP1 acts as a GTPase‐activating protein for human ADP‐ribosylation factor‐like 1 protein

Autor: Lien-Hung Huang, Hsiao-Yun Cheng, Ting-Feng Hsiao, Hsiang-Pu Feng, Chia-Jung Yu, Jia-Wei Hsu, Tai-Wei Lin

Publikováno v: The FASEB Journal. 35

ADP-ribosylation factors (Arfs) and Arf-like (Arl) GTPases are key regulators of intracellular vesicle trafficking and Golgi structure. Both Arf and Arl proteins cycle between active GTP-bound and inactive GDP-bound forms, where guanine nucleotide ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b0bec47ed8eec900cb59e79234ee4c
https://doi.org/10.1096/fj.202000818rr

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Quantitative proteomics reveals a novel role of karyopherin alpha 2 in cell migration through the regulation of vimentin-pErk protein complex levels in lung cancer

Autor: Chun-I Wang, Hsiang-Pu Feng, Chih-Liang Wang, Yu-Sun Chang, Chia-Jung Yu, Pei-Jun Liu, Jau-Song Yu, Yi-Cheng Wu

Publikováno v: Journal of proteome research. 14(4)

Karyopherin alpha 2 (KPNA2) is overexpressed in various human cancers and is associated with cancer invasiveness and poor prognosis. Herein, to understand the essential role of KPNA2 protein complexes in cancer progression, we applied stable isotope

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe0d7b1da980837d391021d7344343c
https://pubmed.ncbi.nlm.nih.gov/25728791

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Dissertation/ Thesis

Characterization of KPNA2 interactome and its physiological function in non-small cell lung cancer

Autor: Hsiang Pu Feng, 馮香菩

102
The process of nucleocytoplasmic shuttling is mediated by karyopherins. Dysregulated expression of karyopherins may trigger oncogenesis through aberrant distribution of cancer-associated proteins. Importin subunit alpha-2 (KPNA2) is overexpr

Externí odkaz: http://ndltd.ncl.edu.tw/handle/04872854422290162463

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Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB

Autor: Hui Mei Hong, Alice L. Yu, Hsiang Pu Feng, Wen-Wei Chang, Hsiu Huan Wang, Tsung Ta Liu, Li Wei

Publikováno v: Breast Cancer Research : BCR

Introduction Heat shock proteins (HSPs) are normally induced under environmental stress to serve as chaperones for maintenance of correct protein folding but they are often overexpressed in many cancers, including breast cancer. The expression of Hsp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4428deb87375c3bb18a5c70d85f1ebbf
https://pubmed.ncbi.nlm.nih.gov/22023707

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