Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hsiang M. Wen"'
Publikováno v:
International Journal of Biochemistry Research & Review. 5:73-81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41b1f0c943a281ffbf80985b59adc156
https://doi.org/10.9734/ijbcrr/2015/8940
https://doi.org/10.9734/ijbcrr/2015/8940
Autor:
Henry L. Paulson, Pedro Gonzalez-Alegre, Kara L. Gordon, Kevin A. Glenn, Nicole M. Bode, Hsiang M. Wen
Publikováno v:
Neuroscience. 224:160-171
DYT1 dystonia is a dominantly inherited, disabling neurological disorder with low penetrance that is caused by the deletion of a glutamic acid (ΔE) in the protein torsinA. We previously showed that torsinA(wt) is degraded through macroautophagy whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb5536600a8cf1aa74538e50d4394ab5
https://doi.org/10.1016/j.neuroscience.2012.08.023
https://doi.org/10.1016/j.neuroscience.2012.08.023
Publikováno v:
Journal of Biological Chemistry. 283:12717-12729
Post-translational modification of proteins regulates many cellular processes. Some modifications, including N-linked glycosylation, serve multiple functions. For example, the attachment of N-linked glycans to nascent proteins in the endoplasmic reti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbf9c26c414c33c1e301553f9551562f
https://doi.org/10.1074/jbc.m709508200
https://doi.org/10.1074/jbc.m709508200
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135591 (2015)
PLoS ONE
PLoS ONE
Alpha-1 antitrypsin deficiency is the leading cause of childhood liver failure and one of the most common lethal genetic diseases. The disease-causing mutant A1AT-Z fails to fold correctly and accumulates in the endoplasmic reticulum (ER) of the live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bfed8c2d9314f8f969686f49f57377
http://europepmc.org/articles/PMC4546667?pdf=render
http://europepmc.org/articles/PMC4546667?pdf=render
Autor:
Bradley A. Hamilton, Hsiang M. Wen, Nandita S. Raikwar, Christie P. Thomas, Diana Zepeda-Orozco
Publikováno v:
Physiological Reports
Proximal tubule cell (PTC) proliferation is critical for tubular regeneration and recovery from acute kidney injury. Epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF‐A) are important for the maintenance of tubulointerstiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c0e3603409e49f35f6f9d08527751e5
https://doi.org/10.14814/phy2.13453
https://doi.org/10.14814/phy2.13453
Publikováno v:
Biochemical and biophysical research communications. 418(1)
A significant fraction of all proteins are misfolded and must be degraded. The ubiquitin–proteasome pathway provides an essential protein quality control function necessary for normal cellular homeostasis. Substrate specificity is mediated by prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5fc40a7d601ccb6df090ad2d1c597fd
https://pubmed.ncbi.nlm.nih.gov/22227190
https://pubmed.ncbi.nlm.nih.gov/22227190
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b902ebbfc7de7b85190b95891eb94d34
https://doi.org/10.1096/fasebj.24.1_supplement.lb151
https://doi.org/10.1096/fasebj.24.1_supplement.lb151
Autor:
Sue M. Travis, Sokol V. Todi, Hsiang M. Wen, Mário N. Laço, Henry L. Paulson, Brett J. Winborn
Publikováno v:
The Journal of biological chemistry. 282(40)
Ataxin-3, a deubiquitinating enzyme, is the disease protein in spinocerebellar ataxia type 3, one of many neurodegenerative disorders caused by polyglutamine expansion. Little is known about the cellular regulation of ataxin-3. This is an important i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf888f5e0e50ce43d194ae89c252db2
https://pubmed.ncbi.nlm.nih.gov/17693639
https://pubmed.ncbi.nlm.nih.gov/17693639