Výsledky vyhledávání - "Hsiang Ling Teo"

Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling

Autor: Xi Xiao Huang, Ley Moy Ng, Po-Hsien Lee, Peiyong Guan, Mun Juinn Chow, Aisyah Binte Mohamed Bashir, Meina Lau, Kenric Yi Shu Tan, Zhimei Li, Jason Yongsheng Chan, Jing Han Hong, Sheng Rong Ng, Hsiang Ling Teo, Daniela Rhodes, Patrick Tan, Puay Hoon Tan, Donald P. McDonnell, Bin Tean Teh

Point mutations in the ligand binding domain of retinoic acid receptor alpha (RARα) have been implicated in breast fibroepithelial tumors development. However, their role in the tumorigenesis of solid tumors is currently unknown. In this study, usin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6525e666c44278b9806d62066b8b6ffe
https://doi.org/10.1101/2022.12.01.518133

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Akademický článek

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions.

Autor: Yan Ting Lim, Nayana Prabhu, Lingyun Dai, Ka Diam Go, Dan Chen, Lekshmy Sreekumar, Louise Egeblad, Staffan Eriksson, Liyan Chen, Saranya Veerappan, Hsiang Ling Teo, Chris Soon Heng Tan, Johan Lengqvist, Andreas Larsson, Radoslaw M Sobota, Pär Nordlund

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0208273 (2018)

Metabolite-protein interactions define the output of metabolic pathways and regulate many cellular processes. Although diseases are often characterized by distortions in metabolic processes, efficient means to discover and study such interactions dir

Externí odkaz: https://doaj.org/article/dcb759615b25496c939a0c9fb00a7898

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The human telomeric nucleosome displays distinct structural and dynamic properties

Autor: Nikolay Korolev, Hsiang Ling Teo, Nikolay V. Berezhnoy, Aghil Soman, Daniela Rhodes, Vincent Olieric, Lars Nordenskiöld, Chong Wai Liew

Publikováno v: Nucleic Acids Research

Telomeres protect the ends of our chromosomes and are key to maintaining genomic integrity during cell division and differentiation. However, our knowledge of telomeric chromatin and nucleosome structure at the molecular level is limited. Here, we ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c62081481a73bb1aaba58540b0354d7
https://pubmed.ncbi.nlm.nih.gov/32374876

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Human AKTIP interacts with ESCRT proteins and functions at the midbody in cytokinesis

Autor: Chong Wai Liew, Mattia La Torre, Colin L. Stewart, Brian Burke, Yolanda Olmos, Isabella Saggio, Chiara Merigliano, Domenico Raimondo, Fiammetta Vernì, Daniela Rhodes, Irene Chiolo, Jeremy G. Carlton, Graham D. Wright, Hsiang Ling Teo, Simona Del Giudice, Alexandre Chojnowski, Wah Ing Goh, Romina Burla

To complete mitosis, the intercellular bridge that links daughter cells needs to be cleaved. This abscission step is carried out by the sequential recruitment of ESCRT proteins at the midbody. We report here that a new factor, named AKTIP, works in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd9e21723ebc00fa9347ade28df87fe
https://doi.org/10.1101/2020.01.19.911891

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AKTIP interacts with ESCRT I and is needed for the recruitment of ESCRT III subunits to the midbody

Publikováno v: PLoS Genetics
PLoS Genetics, Vol 17, Iss 8, p e1009757 (2021)

To complete mitosis, the bridge that links the two daughter cells needs to be cleaved. This step is carried out by the endosomal sorting complex required for transport (ESCRT) machinery. AKTIP, a protein discovered to be associated with telomeres and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f02dff5faa82d6de11a87c126134e8
https://doi.org/10.1371/journal.pgen.1009757

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