Targeting Pyk2 to β1-Integrin-Containing Focal Contacts Rescues Fibronectin-Stimulated Signaling and Haptotactic Motility Defects of Focal Adhesion Kinase-Null Cells

Autor: Klingbeil, Candice K., Hauck, Christof R., Hsia, Datsun A., Jones, K. C., Reider, Shannon R., Schlaepfer, David D.

Publikováno v: The Journal of Cell Biology, 2001 Jan 01. 152(1), 97-110.

Externí odkaz: https://www.jstor.org/stable/1620266

v-Src SH3-enhanced Interaction with Focal Adhesion Kinase at β1 Integrin-containing Invadopodia Promotes Cell Invasion

Autor: Hauck, Christof R. ^{‡, §}, Hsia, Datsun A. ^{‡, §}, Ilic, Dusko ^¶, Schlaepfer, David D. ^{‡, §, ‖}

Publikováno v: In Journal of Biological Chemistry 12 April 2002 277(15):12487-12490

NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator

Autor: Izumiya, Yoshihiro, Izumiya, Chie, Hsia, Datsun, Ellison, Thomas J, Luciw, Paul A, Kung, Hsing-Jien

Publikováno v: Izumiya, Yoshihiro; Izumiya, Chie; Hsia, Datsun; Ellison, Thomas J; Luciw, Paul A; & Kung, Hsing-Jien. (2009). NF-kappaB serves as a cellular sensor of Kaposi's sarcoma-associated herpesvirus latency and negatively regulates K-Rta by antagonizing the RBP-Jkappa coactivator.. Journal of virology, 83(9), 4435-4446. UC Office of the President: California HIV/AIDS Research Program. Retrieved from: http://www.escholarship.org/uc/item/06w534p7

Successful viral replication is dependent on a conducive cellular environment; thus, viruses must be sensitive to the state of their host cells. We examined the idea that an interplay between viral and cellular regulatory factors determines the switc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::5d91b02a553e9f1be6d3fdaabc26bcf7
http://www.escholarship.org/uc/item/06w534p7

Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells

Autor: Hauck, Christof R., Sieg, David J., Hsia, Datsun A., Loftus, Joseph C., Gaarde, William A., Monia, Brett P., Schlaepfer, David D.

Elevated focal adhesion kinase (FAK) expression in human tumor cells has been correlated with an increased cell invasion potential. In cell culture, studies with FAK-null fibroblasts have shown that FAK function is required for cell migration. To det

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______715::e7498e33339a92cbfcbce74f79eb4f87

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.