Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hshi-chi Koo"'
Autor:
Jeffrey A. Kazzaz, Marlene S. Strayer, Jichuan Wu, Daniel J. Malone, Hshi-chi Koo, Thomas H. Shaffer, Jonathan M. Davis, David S. Strayer, Marla R. Wolfson
Publikováno v:
Pulmonary Medicine, Vol 2011 (2011)
We compared lung delivery methods of recombinant adenovirus (rAd): (1) rAd suspended in saline, (2) rAd suspended in saline followed by a pulse-chase of a perfluorochemical (PFC) liquid mixture, and (3) a PFC-rAd suspension. Cell uptake, distribution
Externí odkaz:
https://doaj.org/article/4f3fc23b5ca449889e77e4a27e8126e1
Publikováno v:
Free Radical Biology and Medicine. 45:1143-1149
Exposure of lung epithelial cells to hyperoxia results in the generation of excess reactive oxygen species (ROS), cell damage, and production of proinflammatory cytokines (interleukin-8; IL-8). Although activation of the NF-κB and c-Jun N-terminal k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbae86afdb0b1a2569ad322052844c9f
https://doi.org/10.1016/j.freeradbiomed.2008.07.006
https://doi.org/10.1016/j.freeradbiomed.2008.07.006
Publikováno v:
Free Radical Biology and Medicine. 42:1517-1523
Hyperoxia and pulmonary infections are well known to increase the risk of acute and chronic lung injury in newborn infants, but it is not clear whether hyperoxia directly increases the risk of pneumonia. The purpose of this study was to examine: (1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba14c07c78ea69813e82c69ad7612b9
https://doi.org/10.1016/j.freeradbiomed.2007.02.003
https://doi.org/10.1016/j.freeradbiomed.2007.02.003
Autor:
Jeffrey A. Kazzaz, Thomas H. Shaffer, Eric Hamilton, Ansamma Joseph, Hshi Chi Koo, Marla R. Wolfson, Jonathan M. Davis, Luca Brunelli
Publikováno v:
Pediatric Research. 60:65-70
Previous studies suggest acute lung injury (ALI) in premature newborns is associated with relative deficiency of antioxidant enzymes that may be ameliorated by recombinant human superoxide dismutase (rhSOD). Perfluorochemicals (PFCs) are distributed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b500c92562bdb8ddd199a6aca5ac0a8
https://doi.org/10.1203/01.pdr.0000219392.73509.70
https://doi.org/10.1203/01.pdr.0000219392.73509.70
Autor:
Yuchi Li, Ansamma Joseph, J. Andres Melendez, Jeffrey A. Kazzaz, Jonathan M. Davis, A. Chander, S. Hella Harkness, Yuko Arita, Hshi-chi Koo
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 290:L978-L986
Reactive oxygen species (ROS) can cause cell injury and death via mitochondrial-dependent pathways, and supplementation with antioxidants has been shown to ameliorate these processes. The c-Jun NH2-terminal kinase (JNK) pathway has been shown to play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab97b95a8738a01cf59a4b025bc2fe4d
https://doi.org/10.1152/ajplung.00296.2005
https://doi.org/10.1152/ajplung.00296.2005
Autor:
Dimitrios Hatzis, Jonathan M. Davis, Yuchi Li, Hshi-chi Koo, Harry Opsimos, Marlene S. Strayer, Philip L. Ballard, Jeffrey A. Kazzaz, Simcha Pollack
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 288:L718-L726
Prolonged exposure to supraphysiological oxygen concentrations results in the generation of reactive oxygen species, which can cause significant lung injury in critically ill patients. Supplementation with human recombinant antioxidant enzymes (AOE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c52013d397decc9b9b4c6f80e22266
https://doi.org/10.1152/ajplung.00456.2003
https://doi.org/10.1152/ajplung.00456.2003
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:779-783
Oxidant insults can lead to apoptotic and nonapoptotic cell death. Lung epithelial cells exposed to high levels of oxygen do not die via apoptosis, but through a much slower, morphologically distinct process involving cell and nuclear swelling. In co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dda54457ba2a92944aa30cfc5bfddba
https://doi.org/10.1165/rcmb.2003-0087rc
https://doi.org/10.1165/rcmb.2003-0087rc
Autor:
Lin L. Mantell, Anatoliy M. Ilizarov, Jeffrey A. Kazzaz, Hshi-chi Koo, Stuart Horowitz, Simcha Pollack, Yuchi Li, Ritu Bhapat, Jonathan M. Davis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 24:436-441
To determine whether overexpression of antioxidant enzymes in lung epithelial cells prevents damage from oxidant injury, stable cell lines were generated with complementary DNAs encoding manganese superoxide dismutase (MnSOD) and/or catalase (CAT). C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::427e5804d15c4aac6bf9025aacf6e97a
https://doi.org/10.1165/ajrcmb.24.4.4240
https://doi.org/10.1165/ajrcmb.24.4.4240
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 266:E129-E135
Growth factors may be mediators of local and systemic factors that enhance bone formation. This study examined the effect of treadmill exercise and ovine growth hormone administration on levels of insulin-like growth factor I (IGF-I) in serum (ng/ml)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefd6c9c3ced606480b9757602808238
https://doi.org/10.1152/ajpendo.1994.266.1.e129
https://doi.org/10.1152/ajpendo.1994.266.1.e129
Autor:
Daniel J. Malone, Hshi-chi Koo, David S. Strayer, Marla R. Wolfson, Jonathan M. Davis, Thomas H. Shaffer, Marlene S. Strayer, Jichuan Wu, Jeffrey A. Kazzaz
Publikováno v:
Pulmonary Medicine
Pulmonary Medicine, Vol 2011 (2011)
Pulmonary Medicine, Vol 2011 (2011)
We compared lung delivery methods of recombinant adenovirus (rAd): (1) rAd suspended in saline, (2) rAd suspended in saline followed by a pulse-chase of a perfluorochemical (PFC) liquid mixture, and (3) a PFC-rAd suspension. Cell uptake, distribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565b12ee29f2cfad86f3755230e9d216
https://pubmed.ncbi.nlm.nih.gov/21876799
https://pubmed.ncbi.nlm.nih.gov/21876799