Zobrazeno 1 - 10
of 317
pro vyhledávání: '"Hsd3b2"'
Autor:
Yiyi Zuo, Dongqing Zha, Yue Zhang, Wan Yang, Jie Jiang, Kangning Wang, Runze Zhang, Ziyi Chen, Qing He
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionChronic kidney disease (CKD) presents a critical global health challenge, marked by the progressive decline of renal function. This study explores the role of the 3β-hydroxysteroid dehydrogenase type 2 enzyme (HSD3B2) and the steroid hor
Externí odkaz:
https://doaj.org/article/13907c578d76470bac49ff588cc8b2cc
Autor:
Takashi Yazawa, Yugo Watanabe, Yuko Yokohama, Yoshitaka Imamichi, Kazuya Hasegawa, Ke-ichi Nakajima, Takeshi Kitano, Takanori Ida, Takahiro Sato, Mohammad Sayful Islam, Akihiro Umezawa, Satoru Takahashi, Yasuhito Kato, Sharmin Jahan, Jun-ichi Kawabe
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
3β-Hydroxysteroid dehydrogenases (3β-HSDs) catalyze the oxidative conversion of delta (5)-ene-3-beta-hydroxy steroids and ketosteroids. Human 3β-HSD type 2 (HSD3B2) is predominantly expressed in gonadal and adrenal steroidogenic cells for producin
Externí odkaz:
https://doaj.org/article/8b8186365c784724afed80dc9e31ad03
Autor:
Akeem Babatunde Sikiru, Muibat Adesola Adeniran, Karimot Akinola, Himanshu Behera, G. Kalaignazhal, Stephen Sunday Acheneje Egena
Publikováno v:
Middle East Fertility Society Journal, Vol 28, Iss 1, Pp 1-16 (2023)
Abstract Background Polycystic ovary syndrome (PCOS) is the most typical endocrine disorder affecting women worldwide. Although the etiology of PCOS is not fully understood, genetic factors are believed to play an essential role in its pathogenesis.
Externí odkaz:
https://doaj.org/article/7131d7de290c4e7d9a31ac8f5e90c1cf
Autor:
Nina Makretskaya, Natalia Kalinchenko, Inna Tebieva, Sofya Ionova, Rena Zinchenko, Andrey Marakhonov, Anatoly Tiulpakov
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundCongenital adrenal hyperplasia (CAH) caused by 3β-HSD deficiency is a rare form of congenital adrenal deficiency with an autosomal recessive type of inheritance. Previously we have demonstrated that a single nucleotide variant (SNV) p.Trp2
Externí odkaz:
https://doaj.org/article/5e5c7612678946a68f9a3c87d1f9c23b
Autor:
Asmahane Ladjouze, Malcolm Donaldson, Ingrid Plotton, Nacima Djenane, Kahina Mohammedi, Véronique Tardy-Guidollet, Delphine Mallet, Kamélia Boulesnane, Zair Bouzerar, Yves Morel, Florence Roucher-Boulez
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Background3β-hydroxysteroid dehydrogenase 2 (3βHSD2) deficiency is a rare form of congenital adrenal hyperplasia (CAH), with fewer than 200 cases reported in the world literature and few data on outcomes.Patients and MethodsWe report a mixed longit
Externí odkaz:
https://doaj.org/article/f02b49e95a504f2db237a481c5202d46
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Haisen Zhang, Aihua Wang, Huatao Chen, Tiantian Ma, Jing Zhang, Luda Yang, Tao Pan, Hsu Wen Chao, Dongyao Liu, Xiaoyu Wang, Yaping Jin, Linlin Zhang, Haizhen Jiang, Lijia Zhao
Publikováno v:
Theriogenology. 174:9-19
The circadian clock system plays an important role in regulating testosterone synthesis in mammals. Male Bmal1-/- mice are infertile with low serum testosterone levels and decreased expression of testicular steroidogenic genes, suggesting that circad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bd7503f73c8f8f4a1603fd368530db
https://doi.org/10.1016/j.theriogenology.2021.06.023
https://doi.org/10.1016/j.theriogenology.2021.06.023
Publikováno v:
Advances in Clinical and Experimental Medicine. 30:289-299
Background 3β-HSD deficiency is a rare type of congenital adrenal hyperplasia (CAH), which is caused by HSD3B2 gene mutations. Objectives In order to improve the understanding and diagnosis of the disease, we analyzed and summarized the clinical cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4517dcf430d6e9c6ad9c61d472c2f431
https://doi.org/10.17219/acem/131220
https://doi.org/10.17219/acem/131220