Formylation facilitates the reduction of oxidized initiator methionines.

Autor: Tan R; Department of Biology, University of Rochester, Rochester, NY 14627., Hoare M; Department of Biology, University of Rochester, Rochester, NY 14627., Bellomio P; Department of Biology, University of Rochester, Rochester, NY 14627., Broas S; Department of Biology, University of Rochester, Rochester, NY 14627., Camacho K; Department of Biology, University of Rochester, Rochester, NY 14627., Swovick K; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Welle KA; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Hryhorenko JR; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Ghaemmaghami S; Department of Biology, University of Rochester, Rochester, NY 14627.; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Nov 12; Vol. 121 (46), pp. e2403880121. Date of Electronic Publication: 2024 Nov 05.

Proteome Birthdating Reveals Age-Selectivity of Protein Ubiquitination.

Autor: Meadow ME; Department of Biology, University of Rochester, New York, USA; Medical Scientist Training Program, University of Rochester, New York, USA., Broas S; Department of Biology, University of Rochester, New York, USA., Hoare M; Department of Biology, University of Rochester, New York, USA., Alimohammadi F; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, USA., Welle KA; University of Rochester Mass Spectrometry Resource Laboratory, New York, USA., Swovick K; University of Rochester Mass Spectrometry Resource Laboratory, New York, USA., Hryhorenko JR; University of Rochester Mass Spectrometry Resource Laboratory, New York, USA., Martinez JC; Department of Biology, University of Rochester, New York, USA., Biashad SA; Department of Biology, University of Rochester, New York, USA., Seluanov A; Department of Biology, University of Rochester, New York, USA; Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Gorbunova V; Department of Biology, University of Rochester, New York, USA; Department of Medicine, University of Rochester Medical Center, Rochester, New York, USA., Buchwalter A; Cardiovascular Research Institute, University of California San Francisco, San Francisco, California, USA., Ghaemmaghami S; Department of Biology, University of Rochester, New York, USA; University of Rochester Mass Spectrometry Resource Laboratory, New York, USA. Electronic address: sina.ghaemmaghami@rochester.edu.

Publikováno v: Molecular & cellular proteomics : MCP [Mol Cell Proteomics] 2024 Jul; Vol. 23 (7), pp. 100791. Date of Electronic Publication: 2024 May 24.

Folding stabilities of ribosome-bound nascent polypeptides probed by mass spectrometry.

Autor: Tan R; Department of Biology, University of Rochester, Rochester, NY 14627., Hoare M; Department of Biology, University of Rochester, Rochester, NY 14627., Welle KA; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Swovick K; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Hryhorenko JR; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627., Ghaemmaghami S; Department of Biology, University of Rochester, Rochester, NY 14627.; Mass Spectrometry Resource Laboratory, University of Rochester Medical Center, Rochester, NY 14627.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Aug 15; Vol. 120 (33), pp. e2303167120. Date of Electronic Publication: 2023 Aug 08.

Protein folding stabilities are a major determinant of oxidation rates for buried methionine residues.

Autor: Walker EJ; Department of Biology, University of Rochester, New York, USA; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, New York, USA., Bettinger JQ; Department of Biology, University of Rochester, New York, USA., Welle KA; University of Rochester Mass Spectrometry Resource Laboratory, University of Rochester, New York, USA., Hryhorenko JR; University of Rochester Mass Spectrometry Resource Laboratory, University of Rochester, New York, USA., Molina Vargas AM; Department of Biomedical Genetics, School of Medicine and Dentistry, University of Rochester, New York, USA; Center for RNA Biology, University of Rochester, New York, USA., O'Connell MR; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, New York, USA; Center for RNA Biology, University of Rochester, New York, USA., Ghaemmaghami S; Department of Biology, University of Rochester, New York, USA; University of Rochester Mass Spectrometry Resource Laboratory, University of Rochester, New York, USA. Electronic address: sina.ghaemmaghami@rochester.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2022 May; Vol. 298 (5), pp. 101872. Date of Electronic Publication: 2022 Mar 26.

Publisher Correction: Global analysis of protein degradation in prion infected cells.

Autor: Hutti CR; Department of Biology, University of Rochester, New York, 14627, USA., Welle KA; University of Rochester Mass Spectrometry Resource Laboratory, New York, 14627, USA., Hryhorenko JR; University of Rochester Mass Spectrometry Resource Laboratory, New York, 14627, USA., Ghaemmaghami S; Department of Biology, University of Rochester, New York, 14627, USA. sina.ghaemmaghami@rochester.edu.; University of Rochester Mass Spectrometry Resource Laboratory, New York, 14627, USA. sina.ghaemmaghami@rochester.edu.

Publikováno v: Scientific reports [Sci Rep] 2020 Jul 28; Vol. 10 (1), pp. 12952. Date of Electronic Publication: 2020 Jul 28.