Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hristo Zlatev"'
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-7 (2023)
Abstract Background Kidney transplantation suffers from a shortage of donor organs. Despite this, a lot of grafts are discarded due to inadequate quality. As many kidneys are afflicted by transient filtration failure early after preservation, classic
Externí odkaz:
https://doaj.org/article/a56322fc229f452683e6a028d9370aa5
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract The influence of erythrocytes and oxygen concentration on kidneys during long-term normothermic kidney perfusion is under debate. This study compares acellular and erythrocyte-based NMP with focus on oxygen delivery to the tissue as well as
Externí odkaz:
https://doaj.org/article/6f60af019a114c1dad4c0203b3fadbe4
Autor:
Thomas Minor, Charlotte vonHorn, Hristo Zlatev, Fuat Saner, Melanie Grawe, Bastian Lüer, Eva‐Maria Huessler, Nils Kuklik, Andreas Paul
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 12, Pp 2918-2927 (2022)
Abstract Abrupt return to normothermia has been shown a genuine factor contributing to graft dysfunction after transplantation. This study tested the concept to mitigate reperfusion injury of liver grafts by gentle warming‐up using ex vivo machine
Externí odkaz:
https://doaj.org/article/8df2e2780bd14330a7accc246490feb5
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1880 (2021)
Background: Warm reperfusion after previous cold storage has been shown to have a negative impact on mitochondrial function of organ grafts. Here, we wanted to investigate whether a more controlled warming up of the cold graft by ex vivo machine perf
Externí odkaz:
https://doaj.org/article/884c702cd1f74d31ad604ab6b80ad43d
Background Sudden restoration of normothermic conditions upon reperfusion of cold-stored grafts has been suggested to entail a massive energy demand not yet met by the cells that still suffer from hypothermic torpor. An adapted and gentle rise of gra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf87644659081537bf61a6eaf921ba3
https://www.ncbi.nlm.nih.gov/pubmed/34747502
https://www.ncbi.nlm.nih.gov/pubmed/34747502
Publikováno v:
Biomolecules; Volume 11; Issue 12; Pages: 1880
Background: Warm reperfusion after previous cold storage has been shown to have a negative impact on mitochondrial function of organ grafts. Here, we wanted to investigate whether a more controlled warming up of the cold graft by ex vivo machine perf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::8655101ae2b3cec22f6a7c87387ed9f9
Publikováno v:
Transplantation. 106(5)
Background Normothermic machine perfusion (NMP) provides a promising strategy for preservation and conditioning of marginal organ grafts. However, at present high logistic effort limits normothermic renal perfusion to a short, postponed machine perfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a28d73176b2afb1548e0d1ed0ac5c52
https://pubmed.ncbi.nlm.nih.gov/34172643
https://pubmed.ncbi.nlm.nih.gov/34172643
Publikováno v:
European Journal of Pharmaceutical Sciences. 86:58-66
Purpose: We have examined the uptake routes by which breast cancer cells internalize different formulations of nitrogen containing bisphosphonates (N-BPs). Methods: Cell viability was assessed with the tetrazolium colorimetric test (MTT assay) after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da0945ced1976233420a6273b6972bb
https://doi.org/10.1016/j.ejps.2016.02.016
https://doi.org/10.1016/j.ejps.2016.02.016
Autor:
Hannu Mönkkönen, Johanna Räikkönen, Philippe Clézardin, Jorma A. Määttä, Ismahene Benzaid, Satu Arkko, Hristo Zlatev, Jukka Mönkkönen
Publikováno v:
Cancer Letters. 357(1):279-285
Zoledronate (ZOL) inhibits farnesyl pyrophosphate synthase leading to intracellular accumulation of isopentenyl pyrophosphate/triphosphoric acid 1-adenosin-5'-yl ester 3-(3-methylbut-3-enyl) ester (IPP/ApppI). Cytotoxic Vγ9Vδ2 T cells have been sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d366a1561339b0f2c1ba98a56bbe83d
https://doi.org/10.1016/j.canlet.2014.11.030
https://doi.org/10.1016/j.canlet.2014.11.030