Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Hrishikesh Das"'
Autor:
Marco Mandolesi, Hrishikesh Das, Liset de Vries, Yiqiu Yang, Changil Kim, Manojj Dhinakaran, Xaquin Castro Dopico, Julian Fischbach, Sungyong Kim, Mariia V. Guryleva, Monika Àdori, Mark Chernyshev, Aron Stålmarck, Leo Hanke, Gerald M. McInerney, Daniel J. Sheward, Martin Corcoran, B. Martin Hällberg, Ben Murrell, Gunilla B. Karlsson Hedestam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The continued evolution of SARS-CoV-2 underscores the need to understand qualitative aspects of the humoral immune response elicited by spike immunization. Here, we combine monoclonal antibody (mAb) isolation with deep B cell receptor (BCR)
Externí odkaz:
https://doaj.org/article/dd5bb1c8958649a5ad5a309a8a4fa7ee
Autor:
Xiao Li, Hrishikesh Das, Mayur Pole, Lei Li, Ayoub Soulami, Glenn J. Grant, Darrell R. Herling, Mert Efe
Publikováno v:
Materials & Design, Vol 242, Iss , Pp 113006- (2024)
The friction consolidation method successfully reinforced aluminum 7075 alloy (AA7075) with high-volume fractions (12 and 24 vol%) of titanium diboride (TiB2) by high pressure and severe plastic deformation at elevated temperatures. The consolidated
Externí odkaz:
https://doaj.org/article/20b98335b6dd4ca3b637ae677183a915
Autor:
Qingli Ding, Hrishikesh Das, Piyush Upadhyay, Bryer C. Sousa, Kubra Karayagiz, Adam Powell, Brajendra Mishra
Publikováno v:
Corrosion and Materials Degradation, Vol 4, Iss 1, Pp 142-157 (2023)
Friction stir welded (FSW) aluminum–magnesium lightweight vehicle joints have gained significant interest due to their high strength-to-weight ratio. In this work, the corrosion resistance of this material is analyzed through electrochemical tests,
Externí odkaz:
https://doaj.org/article/2d2320aabadd43a38b57fea2bc2bcc16
Autor:
Leo Hanke, Hrishikesh Das, Daniel J. Sheward, Laura Perez Vidakovics, Egon Urgard, Ainhoa Moliner-Morro, Changil Kim, Vivien Karl, Alec Pankow, Natalie L. Smith, Bartlomiej Porebski, Oscar Fernandez-Capetillo, Erdinc Sezgin, Gabriel K. Pedersen, Jonathan M. Coquet, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Here, the authors isolate and characterize a bispecific monomeric nanobody that induces dimerization of SARS-CoV-2 spike trimers, neutralizes variants of concerns as well as SARS-CoV, and inhibits SARS-CoV-2 infection in mice.
Externí odkaz:
https://doaj.org/article/f14234a7e3914ec1bbba1c457db3bda6
Autor:
Tianhao Wang, Scott Whalen, Xiaolong Ma, Joshua Silverstein, Hrishikesh Das, Madhusudhan R. Pallaka, Angel Ortiz, Timothy Roosendaal, Piyush Upadhyay, Keerti S Kappagantula
Publikováno v:
Journal of Magnesium and Alloys, Vol 10, Iss 1, Pp 110-118 (2022)
A new friction-based riveting technique, Rotating Hammer Riveting (RHR), is demonstrated to fully form AZ31 Mg rivet heads in a mere 0.23 s. Heat and pressure generated through severe plastic deformation during the process was sufficient to form the
Externí odkaz:
https://doaj.org/article/66d9de061cf64198a7d4dd43da579127
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract We report on interfacial characteristics and chemistry of bonded Mg-Fe interfaces welded using friction stir assisted scribe technique (FaST). Two pairs of dissimilar joints: (AZ31-DP590) and (Pure Mg-DP590) were studied to shed light on joi
Externí odkaz:
https://doaj.org/article/79c53f4646ed425eb46d1b29433c0ec7
Autor:
Tânia F. Custódio, Hrishikesh Das, Daniel J. Sheward, Leo Hanke, Samuel Pazicky, Joanna Pieprzyk, Michèle Sorgenfrei, Martin A. Schroer, Andrey Yu. Gruzinov, Cy M. Jeffries, Melissa A. Graewert, Dmitri I. Svergun, Nikolay Dobrev, Kim Remans, Markus A. Seeger, Gerald M. McInerney, Ben Murrell, B. Martin Hällberg, Christian Löw
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Here, the authors isolate several nanobodies from a synthetic library that bind the receptor-binding domain (RBD) of SARS-CoV-2 spike protein (S) and neutralize S pseudotyped viruses. Cryo-EM structure of Spike with one nanobody and further biophysic
Externí odkaz:
https://doaj.org/article/b79a9adc234e460f9baa5ef6524bc6bf
Autor:
Leo Hanke, Laura Vidakovics Perez, Daniel J. Sheward, Hrishikesh Das, Tim Schulte, Ainhoa Moliner-Morro, Martin Corcoran, Adnane Achour, Gunilla B. Karlsson Hedestam, B. Martin Hällberg, Ben Murrell, Gerald M. McInerney
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Here, Hanke et al. immunize an alpaca with SARS-CoV-2 spike protein domains and identify a nanobody that binds the receptor binding domain of spike in both the up and down conformations and sterically hinders ACE2 engagement.
Externí odkaz:
https://doaj.org/article/5d6d86e0a27242f592c4fcf292d06534
Autor:
Tianhao Wang, Lei Li, Madhusudhan R. Pallaka, Hrishikesh Das, Scott Whalen, Ayoub Soulami, Piyush Upadhyay, Keerti S. Kappagantula
Publikováno v:
Materials & Design, Vol 198, Iss , Pp 109305- (2021)
Friction Stir Interlocking (FSI) has been applied for joining dissimilar materials with different physical, chemical and mechanical properties. The FSI process combines friction stir welding with mechanical interlocking where two dissimilar sheets ar
Externí odkaz:
https://doaj.org/article/0651bb0b29bc40b68a1f724ff219380d
Autor:
Tobias Ritterhoff, Hrishikesh Das, Götz Hofhaus, Rasmus R. Schröder, Annette Flotho, Frauke Melchior
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Continuous cycles of nucleo-cytoplasmic transport require disassembly of transport receptor-Ran-GTP complexes in the cytoplasm. Here the authors elucidate the specific function of the RanBP2 complex in the disassembly process.
Externí odkaz:
https://doaj.org/article/1f54f589719b4570b7ab83fd1cc8a098