Metabolism of a novel antiarrhythmic agent, bidisomide, in man: use of high resolution mass spectrometry to distinguish desisopropyl bidisomide from desacetyl bidisomide

Autor: Sweeney, D. L., Schoenhard, G. L., Karim, A., Ames, G. B., Liu, N. W. K., Cook, C. S., Hribar, J. D.

Publikováno v: Xenobiotica; Sep1995, Vol. 25 Issue 9, p981, 0p

Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats.

Autor: Paulson SK; Department of Clinical Pharmacokinetics and Bioavailability, G.D. Searle & Co., Skokie, Illinois, USA. Susan.K.Paulson@monsanto.com, Zhang JY, Breau AP, Hribar JD, Liu NW, Jessen SM, Lawal YM, Cogburn JN, Gresk CJ, Markos CS, Maziasz TJ, Schoenhard GL, Burton EG

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2000 May; Vol. 28 (5), pp. 514-21.

Isolation and identification of metabolites of leukotriene A4 hydrolase inhibitor SC-57461 in rats.

Autor: Yuan JH; G. D. Searle, Skokie, IL 60077, USA., Birkmeier J, Yang DC, Hribar JD, Liu N, Bible R, Hajdu E, Rock M, Schoenhard G

Publikováno v: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 1996 Oct; Vol. 24 (10), pp. 1124-33.

Metabolism and pharmacokinetics of nufenoxole in animals and humans: an example of stereospecific hydroxylation of an isoquinuclidine ring.

Autor: Cook CS; Department of Drug Metabolism, G. D. Searle & Co., Skokie, IL 60077., Campion JG, Hribar JD, Karim A

Publikováno v: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1990 Oct; Vol. 20 (10), pp. 1065-80.

The pH dependence of disobutamide-induced clear cytoplasmic vacuoles in cultured cells.

Autor: Ruben Z, Anderson SN, Rorig KJ, Hribar JD, Bible RH Jr

Publikováno v: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) [Proc Soc Exp Biol Med] 1985 Oct; Vol. 180 (1), pp. 84-91.