Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake.

Autor: McMillin SL; Departments of Kinesiology, Biochemistry & Molecular Biology, and Physiology, Brody School of Medicine, East Carolina Diabetes & Obesity Institute, East Carolina University, Greenville, NC 27858, USA., Evans PL; Departments of Kinesiology, Biochemistry & Molecular Biology, and Physiology, Brody School of Medicine, East Carolina Diabetes & Obesity Institute, East Carolina University, Greenville, NC 27858, USA., Taylor WM; Departments of Kinesiology, Biochemistry & Molecular Biology, and Physiology, Brody School of Medicine, East Carolina Diabetes & Obesity Institute, East Carolina University, Greenville, NC 27858, USA., Weyrauch LA; Departments of Kinesiology, Biochemistry & Molecular Biology, and Physiology, Brody School of Medicine, East Carolina Diabetes & Obesity Institute, East Carolina University, Greenville, NC 27858, USA., Sermersheim TJ; Department of Anatomy, Cell Biology & Physiology, and Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Indiana Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Welc SS; Department of Anatomy, Cell Biology & Physiology, and Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Heitmeier MR; Departments of Pediatrics, and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63130, USA., Hresko RC; Departments of Pediatrics, and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63130, USA., Hruz PW; Departments of Pediatrics, and Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO 63130, USA., Koumanov F; Department of Health, University of Bath, Bath BA2 7AY, UK., Holman GD; Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK., Abel ED; Fraternal Order of Eagles Diabetes Research Center, Division of Endocrinology & Metabolism, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA., Witczak CA; Departments of Kinesiology, Biochemistry & Molecular Biology, and Physiology, Brody School of Medicine, East Carolina Diabetes & Obesity Institute, East Carolina University, Greenville, NC 27858, USA.; Department of Anatomy, Cell Biology & Physiology, and Indiana Center for Musculoskeletal Health, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Indiana Center for Diabetes & Metabolic Diseases, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

Publikováno v: Biomolecules [Biomolecules] 2022 Nov 23; Vol. 12 (12). Date of Electronic Publication: 2022 Nov 23.

Identification of druggable small molecule antagonists of the Plasmodium falciparum hexose transporter PfHT and assessment of ligand access to the glucose permeation pathway via FLAG-mediated protein engineering.

Autor: Heitmeier MR; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, United States of America., Hresko RC; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, United States of America., Edwards RL; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, United States of America., Prinsen MJ; High Throughput Screening Center, Washington University School of Medicine, St Louis, MO, United States of America., Ilagan MXG; High Throughput Screening Center, Washington University School of Medicine, St Louis, MO, United States of America., Odom John AR; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, United States of America.; Department of Molecular Microbiology, Washington University School of Medicine, St Louis, MO, United States of America., Hruz PW; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, United States of America.; Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO, United States of America.

Publikováno v: PloS one [PLoS One] 2019 May 09; Vol. 14 (5), pp. e0216457. Date of Electronic Publication: 2019 May 09 (Print Publication: 2019).

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