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In vivo kinetics of blood cholinesterase inhibition by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and physostigmine in rats

Autor: Bajgar, J., Josef Fusek, Patocka, J., Hrdina, V.

Publikováno v: Europe PubMed Central
Scopus-Elsevier

In vivo inhibition of blood acetylcholinesterase activity by 9-amino-1, 2, 3, 4-tetrahydroacridine, its 7-methoxy derivative and physostigmine was studied in rats. Changes of enzyme activity in the blood were continually registered using an automatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2bd68ac48e0f509c6a7d51740cb854cd
https://pubmed.ncbi.nlm.nih.gov/155828

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Detoxication of phosphonothioates and phosphonofluoridates in the rat

Autor: Bajgar J, Josef Fusek, Patocka J, Hrdina V

Publikováno v: Scopus-Elsevier
Europe PubMed Central

0-isopropylmethyl phosphonofluoridate and 0-ethyl-S-(2-dimethylaminoethyl) methylphosphonothioate were i.m. administered in doses of 2 x LD50 to female rats and the blood acetylcholinesterase was continuously monitored using the automatic colorimeter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::39747abf4f088a5aa8a39e80d47b0902
https://pubmed.ncbi.nlm.nih.gov/749462

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