Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Hrayr S, Karagueuzian"'
Autor:
Norishige Morita, MD, PhD, William J. Mandel, MD, Yoshinori Kobayashi, MD, Hrayr S. Karagueuzian, PhD, FACC, FHRS
Publikováno v:
Journal of Arrhythmia, Vol 30, Iss 6, Pp 389-394 (2014)
Animal and emerging clinical studies have demonstrated that increased ventricular fibrosis in a setting of reduced repolarization reserve promotes early afterdepolarizations (EADs) and triggered activity that can initiate ventricular tachycardia and
Externí odkaz:
https://doaj.org/article/429bae1f0160425ea3aabf156ade3de6
Autor:
Arash Pezhouman, Karl J. Okolotowicz, Wesley L. McKeithan, Robert S. Kass, John R. Cashman, Jorge Gomez-Galeno, Kevin J. Sampson, Mark Johnson, Mark Mercola, Hrayr S. Karagueuzian, Daniel P. Ryan
Publikováno v:
Journal of Medicinal Chemistry. 64:5384-5403
Ventricular cardiac arrhythmia (VA) arises in acquired or congenital heart disease. Long QT syndrome type-3 (LQT3) is a congenital form of VA caused by cardiac sodium channel (INaL) SCN5A mutations that prolongs cardiac action potential (AP) and enha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b5c7f0dd305d00d80d3c4b895bff882
https://doi.org/10.1021/acs.jmedchem.0c01545
https://doi.org/10.1021/acs.jmedchem.0c01545
Autor:
Riccardo Olcese, Marina Angelini, Guillaume Calmettes, Antonios Pantazis, James N. Weiss, Hrayr S. Karagueuzian, Kyle Scranton, Nicoletta Savalli, Federica Steccanella, Michela Ottolia, Marvin G. Chang, Arash Pezhouman
Publikováno v:
Journal of General Physiology. 153
Ventricular arrhythmias, a leading cause of sudden cardiac death, can be triggered by cardiomyocyte early afterdepolarizations (EADs). EADs can result from an abnormal late activation of L-type Ca2+ channels (LTCCs). Current LTCC blockers (class IV a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29599b074a5f12513d840f5d20eda4b4
https://doi.org/10.1085/jgp.202012584
https://doi.org/10.1085/jgp.202012584
Publikováno v:
Journal of Arrhythmia, Vol 22, Iss 1, Pp 4-18 (2006)
Externí odkaz:
https://doaj.org/article/c22ecd36c39540c6843651a65a904fdf
Autor:
Sabine Groenke, Eric D Larson, Sarah Alber, Rui Zhang, Scott T Lamp, Xiaoyan Ren, Haruko Nakano, Maria C Jordan, Hrayr S Karagueuzian, Kenneth P Roos, Atsushi Nakano, Catherine Proenza, Kenneth D Philipson, Joshua I Goldhaber
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e81633 (2013)
The origin of sinoatrial node (SAN) pacemaker activity in the heart is controversial. The leading candidates are diastolic depolarization by "funny" current (If) through HCN4 channels (the "Membrane Clock" hypothesis), depolarization by cardiac Na-Ca
Externí odkaz:
https://doaj.org/article/7a330efe679d4ce9a2dd0a073496d0fa
Autor:
Hrayr S. Karagueuzian
Publikováno v:
Cardiac Mapping ISBN: 9781119152637
Cardiac Mapping
Cardiac Mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50df7a7e861a051f995c434b0d4afde6
https://doi.org/10.1002/9781119152637.ch30
https://doi.org/10.1002/9781119152637.ch30
Autor:
Ali A. Sovari, Nooshin Vahdani, Christopher Y. Ko, Arash Pezhouman, Shankar S. Iyer, Aneesh Bapat, Thao P. Nguyen, Hong Cao, Mostafa Ghanim, Michael C. Fishbein, Hrayr S. Karagueuzian
Publikováno v:
The Journal of Physiology. 594:1689-1707
Hypertension is a risk factor for sudden cardiac death caused by ventricular tachycardia and fibrillation (VT/VF). We hypothesized that, in early hypertension, the susceptibility to stress-induced VT/VF increases. We compared the susceptibility of 5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3adf5bebb280d10c8637d0b7c69bf30
https://doi.org/10.1113/jp271318
https://doi.org/10.1113/jp271318
Autor:
Jan P. Kucera, James N. Weiss, Marina Angelini, Yann Prudat, Riccardo Olcese, Enno de Lange, Alan Garfinkel, Roshni V. Madhvani, Nils P. Borgstom, Hrayr S. Karagueuzian
Publikováno v:
The Journal of Physiology. 594:2537-2553
Key points Beat-to-beat alternation (alternans) of the cardiac action potential duration is known to precipitate life-threatening arrhythmias and can be driven by the kinetics of voltage-gated membrane currents or by instabilities in intracellular ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a06004ffce0dcca373fcd8e3b5728ea4
https://doi.org/10.1113/jp271573
https://doi.org/10.1113/jp271573
Autor:
Yann, Prudat, Roshni V, Madhvani, Marina, Angelini, Nils P, Borgstom, Alan, Garfinkel, Hrayr S, Karagueuzian, James N, Weiss, Enno, de Lange, Riccardo, Olcese, Jan P, Kucera
Publikováno v:
The Journal of physiology
Beat-to-beat alternation (alternans) of the cardiac action potential duration is known to precipitate life-threatening arrhythmias and can be driven by the kinetics of voltage-gated membrane currents or by instabilities in intracellular calcium fluxe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20641181206e52c0f74547f6fb285809
Autor:
Guillaume Calmettes, James N. Weiss, Hrayr S. Karagueuzian, Marvin G. Chang, Antonios Pantazis, Federica Steccanella, Marina Angelini, Riccardo Olcese, Nicoletta Savalli, Arash Pezhouman
Publikováno v:
Biophysical Journal. 118:104a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc591372b6624b7a6c37b6097096ab7c
https://doi.org/10.1016/j.bpj.2019.11.723
https://doi.org/10.1016/j.bpj.2019.11.723