Zobrazeno 1 - 10
of 6 390
pro vyhledávání: '"Hplc-Ms/ms"'
Autor:
Rana Morsi, Kilani Ghoudi, Basant Elabyad, Zaina Kadoura, Hind Zeidane, Bayan Al-Meetani, Mohammed A. Meetani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract This study investigated residual levels of carbosulfan and its metabolites in date palm fruit in the UAE using HPLC-MS/MS and QuEChERS method. The method demonstrated excellent linearity (R2 > 0.998), low LOD (0.001–0.04 μg/kg) and LOQ (0
Externí odkaz:
https://doaj.org/article/5cd2628f380f41a29bf11d1d4a687efb
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4877-4887 (2024)
Na Zhang,1,* Yiran Xu,1,2,* Beibei Liang,1 Jinru Zeng,1 Rui Wang,1 Yun Cai1 1Center of Medicine Clinical Research, Department of Pharmacy, Medical Supplies Center, PLA General Hospital, Beijing, People’s Republic of China; 2Department of Ph
Externí odkaz:
https://doaj.org/article/831f6297fa034c428fbee0a07657f4bf
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 199-207 (2024)
Introduction. The presence of the active metabolite (3-hydroxyphenazepam, 3-OH-PHEN), the wide interindividual variability of the therapeutic effect of phenazepam (PHEN), as well as its active moiety in the blood, determine the relevance of therapeut
Externí odkaz:
https://doaj.org/article/14f29716d5054deab514808eb0b7f4c1
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 219-230 (2024)
Introduction. The study of the systemic exposure of a new original drug is an essential part of its preclinical study. 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide is a new selective carbonic anhydrase II inhibitor for the treatment o
Externí odkaz:
https://doaj.org/article/52838cbd2d95414faabcc41820fa7e0e
Publikováno v:
Разработка и регистрация лекарственных средств, Vol 13, Iss 3, Pp 103-116 (2024)
Introduction. Determination of pesticide residues presence in herbal plants and preparations based on them is an important step in confirming safety at the stage of the quality control of herbal plants. The usage of organophosphate pesticides (OPs) f
Externí odkaz:
https://doaj.org/article/c8833f7669214722a336210becea6cc2
Autor:
Ibrahim Baje Syed, Madhavi Nannapaneni
Publikováno v:
Journal of Applied Pharmaceutical Research, Vol 12, Iss 4, Pp 99-113 (2024)
Background: A quick, accurate, reproducible, and straightforward liquid chromatography-tandem mass spectrometry(LC-MS/MS) system employing Atoltavimab, Maftivimab, and Odesivimab as an internal standard for Zanamivir quantification was achieved. Zana
Externí odkaz:
https://doaj.org/article/e38b1af8fc97425fa23ffe0db11ef3b7
Autor:
Hun Hwan Kim, Se Hyo Jeong, Min Yeong Park, Pritam Bhangwan Bhosale, Abuyaseer Abusaliya, Sang Joon Lee, Jeong Doo Heo, Hyun Wook Kim, Je Kyung Seong, Dong Il Kim, Kwang Il Park, Gon Sup Kim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Free radical is a marker in various inflammatory diseases. The antioxidant effect protects us from this damage, which also plays an essential role in preventing inflammation. Inflammation protects the body from biological stimuli, and pro-in
Externí odkaz:
https://doaj.org/article/7197287b969c490f839f50eeffd1f465
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 3, Pp 304-316 (2024)
INTRODUCTION. Systemic exposure studies of a selective carbonic anhydrase II inhibitor, the isoxazole derivative 5-[5-(trifluoromethyl)-1,2-oxazole-3-yl]-furan-2-sulfonamide (TFISA), require evaluating its pharmacokinetics in whole blood because the
Externí odkaz:
https://doaj.org/article/5378cde63e634d08b90e1bdf210283a2
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 3315-3327 (2024)
Yi Zhu,1,2,* Meiling Chen,3,* Chuangzan Yang,1,2 Geng Lu,1,2 Sa Huang,1,2 Meili Chen,3 Yufei Wang,4 Junfeng Ban1– 3 1Guangdong Pharmaceutical University, Guangzhou, People’s Republic of China; 2The Innovation Team for Integrating Pharmacy
Externí odkaz:
https://doaj.org/article/8898249ca4e143568d28fa83a6c472ba
Autor:
Baodong Feng, Linqi Su, Yang Yang, Renyan Liu, Yu Zhang, Lingyi Xin, Li Wang, Zhiming Yang, Xuemei Wei, Qinhua Chen
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
BackgroundUlcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) influenced by multiple factors. Berberine, an isoquinoline alkaloid derived from the root and bark of Coptis chinensis Franch., has shown promise in managing UC, but its
Externí odkaz:
https://doaj.org/article/21dd5383e0ca41b6b9868b874333df13