Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hozeifa M. Hassan"'
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Tuberculosis (TB) is one of the oldest infectious diseases that affected humankind and remains one of the world’s deadliest communicable diseases that could be considered as global emergency, but the discovery and development of isoniazid (INH) in
Externí odkaz:
https://doaj.org/article/0bfb7a79e1ae404fadb55ee2b207012c
Autor:
Jing Yang, Lixin Sun, Lu Wang, Hozeifa M. Hassan, Xuan Wang, Phillip B. Hylemon, Tao Wang, Huiping Zhou, Luyong Zhang, Zhenzhou Jiang
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Triptolide (TP), a diterpenoid isolated from Tripterygium wilfordii Hook F, has an excellent pharmacological profile of immunosuppression and anti-tumor activities, but its clinical applications are severely restricted due to its severe and cumulativ
Externí odkaz:
https://doaj.org/article/836199f5cc3a4a57a65cf304b860ffb3
Autor:
Hozeifa M. Hassan, Jun Li
Publikováno v:
Journal of clinical and translational hepatology. 10(5)
Acute-on-chronic liver failure (ACLF) is a clinical syndrome that develops in patients with chronic liver diseases following a precipitating event and associated with a high mortality rate due to systemic multiorgan failure. Establishing a suitable a
Autor:
Khnsaa Ga Mohammed, Abeer M Eltaher, Tassneem B Hago, Alaa K Mohamed, Abdelgadir A. Abdelgadir, Lamya Aa Mohammed, Tbyan H Aalim, Alia M Ahmed, Hozeifa M Hassan, Tassneem H Aboalbashar
Publikováno v:
Medicinal & Aromatic Plants. 9
Hyperlipidemia is the greatest risk factors that precipitate coronary heart disease. Medicinal may confer hypolipidemic effects in order to compliment the cardiovascular diseases treatment regimen. The aim of this study was to investigate hypolipidem
Publikováno v:
Phytomedicine. 40:140-147
Background Colorectal cancer (CRC) is one of the most common malignancies associated with high mortality rate worldwide. We previously reported that pristimerin inhibits cell growth and induces apoptosis in CRC cells. Hypothesis/Purpose To further un
Autor:
Rong Sun, Zhenzhou Jiang, Hang Yang, Zihang Yuan, Xiaojiaoyang Li, Hozeifa M. Hassan, Luyong Zhang, Runping Liu
Publikováno v:
Toxicology and Applied Pharmacology. 311:12-25
Estrogen-induced cholestasis, known as intrahepatic cholestasis of pregnancy (ICP), is an estrogen-related liver disease that is widely recognized as female or pregnancy-specific. Our previous findings showed that the synthetic estrogen, 17α-ethinyl
Autor:
Tao Wang, Zhenzhou Jiang, Pingping Ding, Hozeifa M. Hassan, Lixin Sun, Luyong Zhang, Yun Zhang, Si-Zhe Dong, Hongli Guo
Publikováno v:
Toxicological Sciences. 152:417-428
Pyrazinamide (PZA) is an indispensable first-line drug used for treatment of tuberculosis which may cause serious hepatotoxicity, however, the mechanisms underlying these toxicities are poorly understood. Cholestasis plays an important role in drug-i
Autor:
Zhenzhou Jiang, Hozeifa M. Hassan, Hongli Guo, Yuming Song, Yun Zhang, Luyong Zhang, Lixin Sun, Pingping Ding, Yijing Su, Tao Wang
Publikováno v:
Journal of Applied Toxicology. 36:1579-1590
Pyrazinamide (PZA) causes serious hepatotoxicity, but little is known about the exact mechanism by which PZA induced liver injury. The peroxisome proliferator-activated receptors alpha (PPARα) is highly expressed in the liver and modulates the intra
Autor:
Mounia Guerram, Luyong Zhang, Zhenzhou Jiang, Hozeifa M. Hassan, Bashir A. Yousef, Aida Mejda Hamdi, Bin Wang
Publikováno v:
Biomedicine & Pharmacotherapy. 79:112-119
Colorectal cancer (CRC) is one of the world's most common cancers with a high mortality rate mainly due to metastasis. Our previous study showed that pristimerin had potent antitumor activities against human CRC cells. In the present study, we furthe
Publikováno v:
Synergy. 11:100068
Pristimerin is a quinonemethide triterpenoid compound that exerts anticancer activities against different cancer cells, including colorectal cancer. The current study aimed to study the cytotoxic and apoptosis-inducing effects of pristimerin alone or