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Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5‐year follow‐up results from the STAMPEDE randomised trial (NCT00268476)

Autor: James, Nicholas D., Clarke, Noel W., Cook, Adrian, Ali, Adnan, Hoyle, Alex P., Attard, Gert, Brawley, Chris D., Chowdhury, Simon, Cross, William R., Dearnaley, David P., Bono, Johann S., Montana, Carlos Diaz, Gilbert, Duncan, Gillessen, Silke, Gilson, Clare, Jones, Rob J., Langley, Ruth E., Malik, Zafar I., Matheson, David J., Millman, Robin, Parker, Chris C., Pugh, Cheryl, Rush, Hannah, Russell, J. Martin, Berthold, Dominic R., Buckner, Michelle L., Mason, Malcolm D., Ritchie, Alastair W.S., Birtle, Alison J., Brock, Susannah J., Das, Prantik, Ford, Dan, Gale, Joanna, Grant, Warren, Gray, Emma K., Hoskin, Peter, Khan, Mohammad M., Manetta, Caroline, McPhail, Neil J., O'Sullivan, Joe M., Parikh, Omi, Perna, Carla, Pezaro, Carmel J., Protheroe, Andrew S., Robinson, Angus J., Rudman, Sarah M., Sheehan, Denise J., Srihari, Narayanan N., Syndikus, Isabel, Tanguay, Jacob, Thomas, Carys W., Vengalil, Salil, Wagstaff, John, Wylie, James P., Parmar, Mahesh K.B., Sydes, Matthew R.

Publikováno v: James, N D, Clarke, N W, Cook, A, Ali, A, Hoyle, A P, Attard, G, Brawley, C D, Chowdhury, S, Cross, W R, Dearnaley, D P, Bono, J S, Montana, C D, Gilbert, D, Gillessen, S, Gilson, C, Jones, R J, Langley, R E, Malik, Z I, Matheson, D J, Millman, R, Parker, C C, Pugh, C, Rush, H, Russell, J M, Berthold, D R, Buckner, M L, Mason, M D, Ritchie, A WS, Birtle, A J, Brock, S J, Das, P, Ford, D, Gale, J, Grant, W, Gray, E K, Hoskin, P, Khan, M M, Manetta, C, McPhail, N J, O'Sullivan, J M, Parikh, O, Perna, C, Pezaro, C J, Protheroe, A S, Robinson, A J, Rudman, S M, Sheehan, D J, Srihari, N N, Syndikus, I, Tanguay, J, Thomas, C W, Vengalil, S, Wagstaff, J, Wylie, J P, Parmar, M KB & Sydes, M R 2022, ' Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5-year follow-up results from the STAMPEDE randomised trial (NCT00268476) ', International Journal of Cancer . https://doi.org/10.1002/ijc.34018

Abiraterone acetate plus prednisolone (AAP) previously demonstrated improved survival in STAMPEDE, a multi-arm, multi-stage platform trial in men starting long-term hormone therapy for prostate cancer. This long-term analysis in metastatic patients w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d41e4f972431efac3e44597e81d1a4a
https://pure.qub.ac.uk/en/publications/3adddebe-1d1a-4134-8495-5f087a1fee9e

Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial

Autor: Parker, Christopher C., James, Nicholas D., Brawley, Christopher D., Clarke, Noel W., Hoyle, Alex P., Ali, Adnan, Ritchie, Alastair W.S., Attard, Gerhardt, Chowdhury, Simon, Cross, William, Dearnaley, David P., Gillessen, Silke, Gilson, Clare, Jones, Robert J., Langley, Ruth E., Malik, Zafar I., Mason, Malcolm D., Matheson, David, Millman, Robin, Russell, J. Martin, Thalmann, George N., Amos, Claire L., Alonzi, Roberto, Bahl, Amit, Birtle, Alison, Din, Omar, Douis, Hassan, Eswar, Chinnamani, Gale, Joanna, Gannon, Melissa R., Jonnada, Sai, Khaksar, Sara, Lester, Jason F., O'Sullivan, Joe M., Parikh, Omi A., Pedley, Ian D., Pudney, Delia M., Sheehan, Denise J., Srihari, Narayanan Nair, Tran, Anna T.H., Parmar, Mahesh K.B., Sydes, Matthew R.

Publikováno v: Parker, C C, James, N D, Brawley, C D, Clarke, N W, Hoyle, A P, Ali, A, Ritchie, A W S, Attard, G, Chowdhury, S, Cross, W, Dearnaley, D P, Gillessen, S, Gilson, C, Jones, R J, Langley, R E, Malik, Z I, Mason, M D, Matheson, D, Millman, R, Russell, J M, Thalmann, G N, Amos, C L, Alonzi, R, Bahl, A, Birtle, A, Din, O, Douis, H, Eswar, C, Gale, J, Gannon, M R, Jonnada, S, Khaksar, S, Lester, J F, O'sullivan, J M, Parikh, O A, Pedley, I D, Pudney, D M, Sheehan, D J, Srihari, N N, Tran, A T H, Parmar, M K B & Sydes, M R 2018, ' Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial ', The Lancet, vol. 392, no. 10162, pp. 2353-2366 . https://doi.org/10.1016/S0140-6736(18)32486-3
Lancet (London, England)
Parker, Christopher C; James, Nicholas D; Brawley, Christopher D; Clarke, Noel W; Hoyle, Alex P; Ali, Adnan; Ritchie, Alastair W S; Attard, Gerhardt; Chowdhury, Simon; Cross, William; Dearnaley, David P; Gillessen, Silke; Gilson, Clare; Jones, Robert J; Langley, Ruth E; Malik, Zafar I; Mason, Malcolm D; Matheson, David; Millman, Robin; Russell, J Martin; ... (2018). Radiotherapy to the primary tumour for newly diagnosed, metastatic prostate cancer (STAMPEDE): a randomised controlled phase 3 trial. Lancet, 392(10162), pp. 2353-2366. Elsevier 10.1016/S0140-6736(18)32486-3

BACKGROUND Based on previous findings, we hypothesised that radiotherapy to the prostate would improve overall survival in men with metastatic prostate cancer, and that the benefit would be greatest in patients with a low metastatic burden. We aimed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996a38e0fa5edd02ec02b4d7ea6fca6c
https://research.manchester.ac.uk/en/publications/06eb0d5c-8aa3-4dca-bf28-5a0bf7f3ce6d

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