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Autor:
Adriano Afonso, Shirley M. Willams, John A. Hey, Hoyan She, Michael Connolly, Maria A. Rivelli, Ronald L. Wolin, Robert E. West
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 8:2157-2162
Sulfonamides derived from 4(5)-(ω-aminoalkyl)-1H-imidazoles containing chain lengths of three- to five-carbons were synthesized. Good to moderate H3 receptor binding affinities were observed for several butyl and pentyl homologs, whereas binding aff