Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Howin Ng"'
Publikováno v:
Translational Oncology, Vol 13, Iss 9, Pp 100796- (2020)
Degree of genomic instability closely correlates with poor prognosis, drug resistance as well as poor survival across human cancer of different origins. This study assessed the relationship between DNA damage response (DDR) and chromosome instability
Externí odkaz:
https://doaj.org/article/4710990b5c1e44b6a1ea60c88cb6bb5a
Autor:
Pfeifer, Matthias, Brem, Reto, Lippert, Timothy P., Boulianne, Bryant, Ho, Howin Ng, Robinson, Mark E., Stebbing, Justin, Feldhahn, Niklas
Publikováno v:
The Journal of Immunology Author Choice
Key Points Combined deficiency of Ssb1 and Ssb2 abrogates early B cell development. SSB1/2 depletion causes defects in proliferation, genome fragility, and apoptosis. Mature B cells largely tolerate SSB1/2 loss.
Induction of programmed DNA damag
Induction of programmed DNA damag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ef160bee254420f3e9120d0ba88ba765
http://europepmc.org/articles/PMC6545462
http://europepmc.org/articles/PMC6545462
Publikováno v:
Translational Oncology, Vol 13, Iss 9, Pp 100796-(2020)
Translational Oncology
Translational Oncology
Degree of genomic instability closely correlates with poor prognosis, drug resistance as well as poor survival across human cancer of different origins. This study assessed the relationship between DNA damage response (DDR) and chromosome instability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f1a21d0d9964690d898f55b1571db2f
https://doi.org/10.1016/j.tranon.2020.100796
https://doi.org/10.1016/j.tranon.2020.100796
Autor:
Pfeifer M; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and.; Division of Cancer, Department of Surgery and Cancer, Imperial College London, W12 0NN London, United Kingdom., Brem R; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and., Lippert TP; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and., Boulianne B; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and., Ho HN; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and., Robinson ME; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and.; Division of Cancer, Department of Surgery and Cancer, Imperial College London, W12 0NN London, United Kingdom., Stebbing J; Division of Cancer, Department of Surgery and Cancer, Imperial College London, W12 0NN London, United Kingdom., Feldhahn N; Centre for Hematology, Department of Medicine, Imperial College London, W12 0NN London, United Kingdom; and n.feldhahn@imperial.ac.uk.
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Jun 15; Vol. 202 (12), pp. 3423-3433. Date of Electronic Publication: 2019 May 13.