Zobrazeno 1 - 10
of 18 375
pro vyhledávání: '"Howells, A."'
Autor:
Anderson, David F., Howells, Aidan S.
Models of reaction networks within interacting compartments (RNIC) are a generalization of stochastic reaction networks. It is most natural to think of the interacting compartments as ``cells'' that can appear, degrade, split, and even merge, with ea
Externí odkaz:
http://arxiv.org/abs/2408.09208
Autor:
Josie MM Evans, Nicole Sergenson, Melanie Dembinsky, Lynne Haahr, Jen Bishop, Anna Howells, Katie Munro, Lesley Price
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Rapid timescales for the design and delivery of research were common during the COVID-19 pandemic. The recruitment and retention of healthcare workers (HCWs) as participants in research studies are notoriously challenging, but thi
Externí odkaz:
https://doaj.org/article/ed4ab5134b024ceb855fa9fc22ce0ca0
Autor:
David Salcedo-Tacuma, Giovanni D. Howells, Coleman McHose, Aimer Gutierrez-Diaz, Jane Schupp, David M. Smith
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract The proteasome plays a crucial role in cellular homeostasis by degrading misfolded, damaged, or unnecessary proteins. Understanding the regulatory mechanisms of proteasome activity is vital, particularly the interaction with activators conta
Externí odkaz:
https://doaj.org/article/6830081c1ed74845937612693fbef732
Autor:
Melissa S. Naugle, Hugo Denis, Véronique J. L. Mocellin, Patrick W. Laffy, Iva Popovic, Line K. Bay, Emily J. Howells
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-12 (2024)
Abstract Reef-building coral populations face unprecedented threats from climate warming. Standing variation in heat tolerance is crucial for evolutionary processes necessary for corals to persist. Yet, the spatial distribution of heat-tolerant coral
Externí odkaz:
https://doaj.org/article/e71e7d98a4ba4e10b94ae0efd82a161e
Publikováno v:
Malaysian Journal of Microbiology, Vol 14 (2018)
Externí odkaz:
https://doaj.org/article/cca1e344ed33434094a22351ec08ee6e
Autor:
Anderson, David F., Howells, Aidan S.
Stochastic reaction networks, which are usually modeled as continuous-time Markov chains on $\mathbb Z^d_{\ge 0}$, and simulated via a version of the "Gillespie algorithm," have proven to be a useful tool for the understanding of processes, chemical
Externí odkaz:
http://arxiv.org/abs/2303.14093
Autor:
Peter James Taylor, Isabel Adeyemi, Katie Marlow, Sarah Cottam, Zerena Airnes, Samantha Hartley, Victoria Howells, Barnaby D. Dunn, Rachel A. Elliott, Mark Hann, Cameron Latham, Catherine Robinson, Clive Turpin, Stephen Kellett
Publikováno v:
Pilot and Feasibility Studies, Vol 10, Iss 1, Pp 1-13 (2024)
Abstract Background Self-harm is a prevalent behaviour that has a major detrimental impact on a person’s life. Psychological therapies have the potential to help, but evidence of effective interventions remains limited. Access and acceptability of
Externí odkaz:
https://doaj.org/article/55bb7bb0d324444da14868ebab1b7f8b
Autor:
Anna B. Jacobsen, Hugh Bostock, James Howells, Bülent Cengiz, Gintaute Samusyte, Martin Koltzenburg, Hossein Pia, Anders Fuglsang‐Frederiksen, Jakob Blicher, Izabella Obál, Henning Andersen, Hatice Tankisi
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 7, Pp 1887-1896 (2024)
Abstract Objective There is a need for sensitive biomarkers in amyotrophic lateral sclerosis (ALS), to enable earlier diagnosis and to help assess potential treatments. The main objective of this study was to compare two potential biomarkers, thresho
Externí odkaz:
https://doaj.org/article/071fbef2b98843f8b72ce2530f44a535
Autor:
Constantinos Demetriou, Naila Abid, Michael Butterworth, Larissa Lezina, Pavandeep Sandhu, Lynne Howells, Ian R. Powley, James H. Pringle, Zahirah Sidat, Omar Qassid, Dave Purnell, Monika Kaushik, Kaitlin Duckworth, Helen Hartshorn, Anne Thomas, Jacqui A. Shaw, Marion MacFarlane, Catrin Pritchard, Gareth J. Miles
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Breast Cancer is the most common cancer among women globally. Despite significant improvements in overall survival, many tumours are refractory to therapy and so novel approaches are required to improve patient outcomes. We have evaluated pa
Externí odkaz:
https://doaj.org/article/e0e42b354faf4f46a4b07334d5c51938
Autor:
Francis D. Pope, Robin Price, Katherine E. Woolley, Carlo Luiu, Mohammed S. Alam, William R. Avis, Suzanne E. Bartington, Dawit Debebe, Zerihun Getaneh, Sheila M. Greenfield, Rachel Howells, Mukesh Khare, Abel Weldetinsae, Chloe Lawson, Sumit K. Mishra, Ben Neal, Karen Newman, Ajit Singh, Bikila Teklu Wodajo, G. Neil Thomas, Faye Wilder
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-8 (2024)
Abstract The World Health Organization estimates that air pollution causes approximately seven million premature deaths worldwide each year. Solutions to air pollution are well known, yet this rarely equates to easily actionable. Here we demonstrate
Externí odkaz:
https://doaj.org/article/c448784d96124c20a85fd5fadbbaa665