Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Howard Yeh"'
Autor:
Mary E. Guckert, A. Kate Sasser, Pamela L. Clemens, Antonio Palumbo, Steen Lisby, Tahamtan Ahmadi, Paul G. Richardson, Linda Basse, Henk M. Lokhorst, Jakub Krejcik, Charlotte Lemech, Jacob P. Laubach, Howard Yeh, Jianping Wang, Torben Plesner, Ulrik Lassen, Monique C. Minnema, Carla de Boer, Hendrik-Tobias Arkenau, Peter Gimsing, Nushmia Z. Khokhar
Publikováno v:
Blood, 128(14), 1821-1828. American Society of Hematology
Blood, 128(14), 1821. American Society of Hematology
Plesner, T, Arkenau, H-T, Gimsing, P, Krejcik, J, Lemech, C, Minnema, M C, Lassen, U, Laubach, J P, Palumbo, A, Lisby, S, Basse, L, Wang, J, Sasser, A K, Guckert, M E, de Boer, C, Khokhar, N Z, Yeh, H, Clemens, P L, Ahmadi, T, Lokhorst, H M & Richardson, P G 2016, ' Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma ', Blood, vol. 128, no. 14, pp. 1821-1828 . https://doi.org/10.1182/blood-2016-07-726729
Blood, 128(14), 1821. American Society of Hematology
Plesner, T, Arkenau, H-T, Gimsing, P, Krejcik, J, Lemech, C, Minnema, M C, Lassen, U, Laubach, J P, Palumbo, A, Lisby, S, Basse, L, Wang, J, Sasser, A K, Guckert, M E, de Boer, C, Khokhar, N Z, Yeh, H, Clemens, P L, Ahmadi, T, Lokhorst, H M & Richardson, P G 2016, ' Phase 1/2 study of daratumumab, lenalidomide, and dexamethasone for relapsed multiple myeloma ', Blood, vol. 128, no. 14, pp. 1821-1828 . https://doi.org/10.1182/blood-2016-07-726729
Daratumumab, a human CD38 immunoglobulin G1 kappa (IgG1κ) monoclonal antibody, has activity as monotherapy in multiple myeloma (MM). This phase 1/2 study investigated daratumumab plus lenalidomide/dexamethasone in refractory and relapsed/refractory
Autor:
Patricia A. Jennings, Mark L. Paddock, Howard Yeh, Rachel Nechushtai, John A. Zuris, Tung A. Nguyen, Syed S. Ali
Publikováno v:
Journal of Biological Chemistry. 287:11649-11655
MitoNEET (mNT) is the founding member of the recently discovered CDGSH family of [2Fe-2S] proteins capable of [2Fe-2S] cluster transfer to apo-acceptor proteins. It is a target of the thiazolidinedione (TZD) class of anti-diabetes drugs whose binding
Publikováno v:
Journal of Biological Chemistry. 277:6923-6928
To elucidate the mechanism by which isoforms of CCAAT/enhancer-binding proteins regulate cyclooxygenase-2 expression, we determined by a novel technique binding of six isoforms of this transactivator to two sequence-specific CCAAT/enhancer-binding pr
Autor:
Cheol, Kwak, Tony Tong Lin, Wu, Hyun Moo, Lee, Hsi Chin, Wu, Sung Joon, Hong, Yen Chuan, Ou, Seok Soo, Byun, Hyou Young, Rhim, Thian, Kheoh, Ying, Wan, Howard, Yeh, Margaret K, Yu, Choung Soo, Kim
Publikováno v:
International journal of urology : official journal of the Japanese Urological Association. 21(12)
To evaluate the safety and efficacy of abiraterone acetate and prednisolone in Korean and Taiwanese patients with metastatic castration-resistant prostate cancer not responding to docetaxel-based chemotherapy.In this single-arm study, 82 metastatic c
Autor:
Hendrik-Tobias Arkenau, Antonio Palumbo, Henk M. Lokhorst, Paul G. Richardson, Mary E. Guckert, Torben Plesner, Peter Gimsing, Linda Basse, Charlotte Lemech, Howard Yeh, Tahamtan Ahmadi, Ulrik Lassen, Nikolai Constantin Brun, Jakub Krejcik, Steen Lisby, Monique C. Minnema
Publikováno v:
Plesner, T, Arkenau, H-T, Lokhorst, H M, Gimsing, P, Krejcik, J, Rose Lemech, C, Minnema, M, Lassen, U N, Ahmadi, T, Yeh, H, Guckert, M, C. Brun, N, Lisby, S, Basse, L, Palumbo, A & Richardson, P G 2014, ' Safety and efficacy of daratumumab with lenalidomide and dexamethasone in relapsed or relapsed, refractory multiple myeloma ', Journal of Clinical Oncology, vol. 32, no. 15, 8533 . https://doi.org/10.1200/jco.2014.32.15_suppl.8533
Plesner, T, Arkenau, H-T, Lokhorst, H M, Gimsing, P, Krejcik, J, Rose Lemech, C, Minnema, M, Lassen, U N, Ahmadi, T, Yeh, H, Guckert, M, C. Brun, N, Lisby, S, Basse, L, Palumbo, A & Richardson, P 2014, ' Safety and efficacy of daratumumab with lenalidomide and dexamethasone in relapsed or relapsed, refractory multiple myeloma ', 50th Annual Meeting of American Society of Clinical Oncology, Chicago, Illinois, United States, 30/05/2014-03/06/2014 . < http://meetinglibrary.asco.org/content/131350-144 >
Plesner, T, Arkenau, H-T, Lokhorst, H M, Gimsing, P, Krejcik, J, Rose Lemech, C, Minnema, M, Lassen, U N, Ahmadi, T, Yeh, H, Guckert, M, C. Brun, N, Lisby, S, Basse, L, Palumbo, A & Richardson, P 2014, ' Safety and efficacy of daratumumab with lenalidomide and dexamethasone in relapsed or relapsed, refractory multiple myeloma ', 50th Annual Meeting of American Society of Clinical Oncology, Chicago, Illinois, United States, 30/05/2014-03/06/2014 . < http://meetinglibrary.asco.org/content/131350-144 >
8533 Background: Daratumumab (DARA) (HuMax-CD38), a human IgG1κ monoclonal antibody effectively mediates destruction of CD38-expressing malignant plasma cells. In the first-in-human dose-escalation...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7b79a9355b4a223cd3d6a4b715ba01
https://portal.findresearcher.sdu.dk/da/publications/86737d0c-389d-4aa8-bb3d-dc30d8dfbb7a
https://portal.findresearcher.sdu.dk/da/publications/86737d0c-389d-4aa8-bb3d-dc30d8dfbb7a
Autor:
Mary E. Guckert, Charlotte Lemech, Howard Yeh, Jacob P. Laubach, Hendrik-Tobias Arkenau, Henk M. Lokhorst, Peter Gimsing, Steen Lisby, Ulrik Lassen, Nikolai Constantin Brun, Monique C. Minnema, Linda Basse, Torben Plesner, Paul G. Richardson, Tahamtan Ahmadi, Jakub Krejcik, Huaibao Feng, Antonio Palumbo
Publikováno v:
Plesner, T, Arkenau, H-T, Lokhorst, H M, Gimsing, P, Krejcik, J, Rose Lemech, C, Minnema, M, Lassen, U N, Laubach, J, Ahmadi, T, Yeh, H, Guckert, M, Feng, H, C. Brun, N, Lisby, S, Basse, L, Palumbo, A & Richardson, P 2014, ' Safety and Efficacy of Daratumumab with Lenalidomide and Dexamethasone in Relapsed or Relapsed, Refractory Multiple Myeloma ', 56th American Society of Hematology Annual Meeting & Exposition, San Fransisco, CA, United States, 06/12/2014-09/12/2014 . < https://ash.confex.com/ash/2014/webprogram/Paper74400.html >
Background: Daratumumab (DARA) (HuMax™-CD38), a human IgG1κ monoclonal antibody effectively mediates destruction of CD38-expressing malignant plasma cells. In the first-in-human dose-escalation study, 42% of heavily pretreated patients with relaps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a5a298fc5352ae9511ded3483cf136
https://portal.findresearcher.sdu.dk/da/publications/e65d2bb7-4f0e-400f-adb8-2beff1f1889c
https://portal.findresearcher.sdu.dk/da/publications/e65d2bb7-4f0e-400f-adb8-2beff1f1889c
Autor:
John A. Zuris, Rachel Nechushtai, Mark L. Paddock, Howard Yeh, Patricia A. Jennings, Tung A. Nguyen, Syed S. Ali
Publikováno v:
Biophysical Journal. 102(3)
MitoNEET is the founding member of the recently discovered CDGSH family of [2Fe-2S] proteins. Its structure contains a unique homodimeric fold with each monomer containing one [2Fe-2S] cluster (1). MitoNEET is a target of the thiazolidinedione (TZD)
Autor:
Hendrik-Tobias Arkenau, Paul G. Richardson, Henk M. Lokhorst, Steen Lisby, Peter Gimsing, Linda Basse, Mary E. Guckert, Antonio Palumbo, Torben Plesner, Jakub Krejcik, Monique C. Minnema, Jacob P. Laubach, Jianping Wang, Ulrik Lassen, A. Kate Sasser, Tahamtan Ahmadi, Charlotte Lemech, Howard Yeh
Publikováno v:
Blood. 126:507-507
Introduction : Daratumumab (DARA) is a human anti-CD38 IgG1κ monoclonal antibody that showed synergistic anti-tumor activity in combination with lenalidomide (LEN) in in vitro preclinical studies (van der Veer M. Haematologica 2011;96(2):284-90). DA
Autor:
Hartmut Goldschmidt, Pieter Sonneveld, Asher Chanan-Khan, Meletios A. Dimopoulos, Robert Z. Orlowski, Donna E. Reece, Antonio Palumbo, Xiang Qin, Andrew Spencer, Himal Amin, Tahamtan Ahmadi, Mary E. Guckert, Howard Yeh, Jordan M. Schecter
Publikováno v:
Journal of Clinical Oncology. 33:TPS8609-TPS8609
TPS8609 Background: Lenalidomide or bortezomib plus low-dose dexamethasone are considered standard of care for relapsed/refractory MM patients. DARA is a human anti-CD38 IgG1κ monoclonal antibody. ...
Autor:
Ke-He Ruan, Kenneth K. Wu, Michael A. Saunders, Mikhail I. Shtivelband, Derek W. Gilroy, Howard Yeh, Wu Guo Deng, Xue Zhong He, Ying Zhu
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16(10)
Cyclooxygenase-2 (COX-2) is an inducible enzyme that plays an important role in several pathophysiological processes, including inflammation, angiogenesis, and tumorigenesis. We have recently observed that COX-2 induction is restrained in proliferati