Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Howard W. Clark"'
Autor:
Ahilanandan Dushianthan, Howard W. Clark, David Brealey, Danny Pratt, James B. Fink, Jens Madsen, Helen Moyses, Lewis Matthews, Tracy Hussell, Ratko Djukanovic, Martin Feelisch, Anthony D. Postle, Michael P. W. Grocott
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract SARS-CoV-2 directly targets alveolar epithelial cells and can lead to surfactant deficiency. Early reports suggested surfactant replacement may be effective in improving outcomes. The aim of the study to assess the feasibility and efficacy o
Externí odkaz:
https://doaj.org/article/a77d36c23f7d4e1287d0bc5878c169f2
Autor:
Ventzislava A. Hristova, Alastair Watson, Raghothama Chaerkady, Matthew S. Glover, Jodie Ackland, Bastian Angerman, Graham Belfield, Maria G. Belvisi, Hannah Burke, Doriana Cellura, Howard W. Clark, Damla Etal, Anna Freeman, Ashley I. Heinson, Sonja Hess, Michael Hühn, Emily Hall, Alex Mackay, Jens Madsen, Christopher McCrae, Daniel Muthas, Steven Novick, Kristoffer Ostridge, Lisa Öberg, Adam Platt, Anthony D. Postle, C. Mirella Spalluto, Outi Vaarala, Junmin Wang, Karl J. Staples, Tom M.A. Wilkinson, on behalf of the MICA II Study group
Publikováno v:
ERJ Open Research, Vol 9, Iss 3 (2022)
Rationale Pulmonary surfactant is vital for lung homeostasis as it reduces surface tension to prevent alveolar collapse and provides essential immune-regulatory and antipathogenic functions. Previous studies demonstrated dysregulation of some individ
Externí odkaz:
https://doaj.org/article/d0133b7993c74d2bbea08bf595e4130e
Autor:
Shane R. Ellis, Emily Hall, Madhuriben Panchal, Bryn Flinders, Jens Madsen, Grielof Koster, Ron.M.A. Heeren, Howard W. Clark, Anthony D. Postle
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100023- (2021)
Mass spectrometry imaging (MSI) visualizes molecular distributions throughout tissues but is blind to dynamic metabolic processes. Here, MSI with high mass resolution together with multiple stable isotope labeling provided spatial analyses of phospha
Externí odkaz:
https://doaj.org/article/39a071a8396f4653aeda60ee0dbd835f
Autor:
Waseem Ahmed, Aneesh Vincent Veluthandath, David J. Rowe, Jens Madsen, Howard W. Clark, Anthony D. Postle, James S. Wilkinson, Ganapathy Senthil Murugan
Publikováno v:
Sensors, Vol 22, Iss 5, p 1744 (2022)
The authors of this study developed the use of attenuated total reflectance Fourier transform infrared spectroscopy (ATR–FTIR) combined with machine learning as a point-of-care (POC) diagnostic platform, considering neonatal respiratory distress sy
Externí odkaz:
https://doaj.org/article/58078707eb0f4fea985ffb32e859a4ea
Autor:
Jens Madsen, Madhuriben H. Panchal, Rose-Marie A. Mackay, Mercedes Echaide, Grielof Koster, Giancarlo Aquino, Nicola Pelizzi, Jesus Perez-Gil, Fabrizio Salomone, Howard W. Clark, Anthony D. Postle
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 10, Pp 1880-1892 (2018)
Secreted pulmonary surfactant phosphatidylcholine (PC) has a complex intra-alveolar metabolism that involves uptake and recycling by alveolar type II epithelial cells, catabolism by alveolar macrophages, and loss up the bronchial tree. We compared th
Externí odkaz:
https://doaj.org/article/29b8394737534019b76dd18cc163d901
Autor:
Elizabeth Reid, Omar F Kamlin, Francesca Orsini, Antonio G De Paoli, Howard W Clark, Roger F Soll, John B Carlin, Peter G Davis, Peter A Dargaville
Publikováno v:
Clinical Trials. :174077452311716
Background: Blinding of treatment allocation from treating clinicians in neonatal randomised controlled trials can minimise performance bias, but its effectiveness is rarely assessed. Methods: To examine the effectiveness of blinding a procedural int
Autor:
Anthony D. Postle, Howard W. Clark, Jim Fink, Jens Madsen, Grielof Koster, Madhuriben Panchal, Ratko Djukanovic, David Brealey, Michael P. W. Grocott, Ahilanandan Dushianthan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb07d818432ceb168ba820de23c07ed
https://eprints.soton.ac.uk/453225/
https://eprints.soton.ac.uk/453225/
Autor:
Peter A, Dargaville, C Omar F, Kamlin, Francesca, Orsini, Xiaofang, Wang, Antonio G, De Paoli, H Gozde, Kanmaz Kutman, Merih, Cetinkaya, Lilijana, Kornhauser-Cerar, Matthew, Derrick, Hilal, Özkan, Christian V, Hulzebos, Georg M, Schmölzer, Ajit, Aiyappan, Brigitte, Lemyre, Sheree, Kuo, Victor S, Rajadurai, Joyce, O'Shea, Manoj, Biniwale, Rangasamy, Ramanathan, Alla, Kushnir, David, Bader, Mark R, Thomas, Mallinath, Chakraborty, Mariam J, Buksh, Risha, Bhatia, Carol L, Sullivan, Eric S, Shinwell, Amanda, Dyson, David P, Barker, Amir, Kugelman, Tim J, Donovan, Markus K, Tauscher, Vadivelam, Murthy, Sanoj K M, Ali, Pete, Yossuck, Howard W, Clark, Roger F, Soll, John B, Carlin, Peter G, Davis, Susan L, Collins
Publikováno v:
JAMA
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(24), 2478-2487. AMER MEDICAL ASSOC
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 326(24), 2478-2487. AMER MEDICAL ASSOC
IMPORTANCE The benefits of surfactant administration via a thin catheter (minimally invasive surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome are uncertain.OBJECTIVE To examine the effect of selective application of MI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::daf260739e007481a4562b1a545b7691
https://europepmc.org/articles/PMC8715350/
https://europepmc.org/articles/PMC8715350/
Autor:
Annette K. Shrive, Jamie R. Littlejohn, Harry M. Williams, William Neale, Stacey Collister, Derek Hood, Stefan Oscarson, Jens Madsen, Howard W. Clark, Trevor J. Greenhough
Human surfactant protein D is a collectin and member of the C-type lectin superfamily of proteins that forms an essential part of the mammalian innate immune system. The collectins have been recognised to not only bind to invading pathogens, allowing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61acc3d6380bafd1f23955b59c36a3f7
https://eprints.keele.ac.uk/10703/1/a59704.pdf
https://eprints.keele.ac.uk/10703/1/a59704.pdf
Publikováno v:
Microporous Materials. 6:115-124
The microporous crystalline aluminophosphate designated AlPO-41 has been synthesized as a pure phase in a mixed wateralcohol system. This synthesis of AlPO-41 avoids the previously reported need for seed crystals to obtain a pure AlPO-41 phase. Al