Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Howard V. Wheal"'
Publikováno v:
The Journal of Physiology. 579:363-373
Hippocampal pyramidal neurones display a Ca2+-dependent K+ current responsible for the slow afterhyperpolarization (IsAHP), a prominent regulator of excitability. There is considerable transmitter convergence onto IsAHP but little information about t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d50a8c8ccb03cde6ab7f25d8122c937
https://doi.org/10.1113/jphysiol.2006.122051
https://doi.org/10.1113/jphysiol.2006.122051
Publikováno v:
Neuroscience. 139:1301-1313
Biochemical and in situ hybridization studies demonstrated that the levels of protein kinase C variants were significantly increased in the hippocampus of the experimental models of epilepsy in rats. In addition it has been demonstrated that protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4efebf36c9a255de16eac88d28be3aef
https://doi.org/10.1016/j.neuroscience.2006.01.014
https://doi.org/10.1016/j.neuroscience.2006.01.014
Publikováno v:
The Journal of Neuroscience. 24:4530-4534
Prolonged modification of intrinsic neuronal excitability is gaining prominence as an activity-dependent form of plasticity. Here we describe a potential synaptic initiation mechanism for these changes in which release of the transmitter glutamate ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f75803953238046b859d9ca22b2140
https://doi.org/10.1523/jneurosci.5356-03.2004
https://doi.org/10.1523/jneurosci.5356-03.2004
Publikováno v:
Neuron. 34(1):107-114
Kainate receptors (KARs) on CA1 pyramidal cells make no detectable contribution to EPSCs. We report that these receptors have a metabotropic function, as shown previously for CA1 interneurons. Brief kainate exposure caused long-lasting inhibition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a34f23d8df594aa03ac732223556838
Publikováno v:
The Journal of Comparative Neurology. 413:619-633
Dendrites of reconstructed hippocampal neurons were analyzed for morphometric, topologic, and fractal parameters (n = 32 quantities) to investigate neuronal groupings and growth characteristics with a common set of assumptions. The structures studied
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32afc21c2910a84f1b3ed6a2dbebc4dd
https://doi.org/10.1002/(sici)1096-9861(19991101)413:4<619::aid-cne10>3.0.co
https://doi.org/10.1002/(sici)1096-9861(19991101)413:4<619::aid-cne10>3.0.co
Publikováno v:
Journal of Neuroscience Methods. 84:49-54
We have developed an on-line archive of neuronal geometry to encourage the use of realistic dendritic structures in morphometry and for neuronal modeling, located at web address www.neuro.soton.ac.uk. Initially we have included full three-dimensional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d479d723b082afb0dc9200f8288a18
https://doi.org/10.1016/s0165-0270(98)00091-0
https://doi.org/10.1016/s0165-0270(98)00091-0
Autor:
Ying Chen, Joachim Kirsch, D. Van Rossum, H. Wieland, W. Maerz, Melitta Schachner, Howard V. Wheal, J. Mitchell
Publikováno v:
Progress in Neurobiology. 55:611-640
The synaptic plasticity that is addressed in this review follows neurodegeneration in the brain and thus has both structural as well as functional components. The model of neurodegeneration that has been selected is the kainic acid lesioned hippocamp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caccdc4519fcd304bf3be8ec1a42a48
https://doi.org/10.1016/s0301-0082(98)00026-4
https://doi.org/10.1016/s0301-0082(98)00026-4
Autor:
Dennis A. Turner, J. Chloë Bulinski, Howard V. Wheal, Nelson Spruston, Thomas G. Ohm, Hanno Roder
Publikováno v:
Progress in Neurobiology. 55:641-650
Recovery after nervous system lesions may lead to partial re-institution of developmental schemes and processes. Here we review several of these proposed schemes, with the conclusion that though some processes may involve re-expression of embryonic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fbc314e100fc6e2cdaf1f4097530d8a
https://doi.org/10.1016/s0301-0082(98)00023-9
https://doi.org/10.1016/s0301-0082(98)00023-9
Publikováno v:
Hippocampus. 7:58-72
There is a sharp contrast between the profuse in vivo axonal arborization of CA3 pyramidal cells in the CA1 area and the low probability of finding pairs of connected CA3-CA1 pyramidal cells in vitro. These anatomical differences contribute to a conn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbe53102dd2c645e91ee4be5787500b6
https://doi.org/10.1002/(sici)1098-1063(1997)7:1<58::aid-hipo6>3.0.co
https://doi.org/10.1002/(sici)1098-1063(1997)7:1<58::aid-hipo6>3.0.co
Autor:
Howard V. Wheal, Christophe Bernard
Publikováno v:
Neuroscience. 67:73-82
Tetanic stimulation of afferents in the stratum radiatum of the CA1 area of the rat hippocampus results in long-term potentiation of excitatory synaptic responses in pyramidal cells. Previous studies have reported a greater increase in the population
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a128d3efd83ffefca4d57dd81e2fc38e
https://doi.org/10.1016/0306-4522(95)00008-7
https://doi.org/10.1016/0306-4522(95)00008-7