Zobrazeno 1 - 10
of 451
pro vyhledávání: '"Howard Scher"'
Autor:
Christina A. Clarke, Kathryn Lang, Girish Putcha, Jonathan P. Beer, Maude Champagne, Andrea Ferris, James H. Godsey, Robert L. Grossman, Jody M. Hoyos, Donald J. Johann, Nancy Krunic, Peter Kuhn, Jerry S. H. Lee, Tara Maddala, Marielena Mata, Jeremiah McDole, Omar Perez, Howard Scher, Mark D. Stewart, Seema Singh Bhan, Qu Zhang, Lauren C. Leiman
Publikováno v:
Clinical and Translational Science, Vol 16, Iss 1, Pp 5-9 (2023)
Externí odkaz:
https://doaj.org/article/7b363a26cae14a86b511585015f714ce
Autor:
Christina A. Clarke, Kathryn Lang, Girish Putcha, Jonathan P. Beer, Maude Champagne, Andrea Ferris, James H. Godsey, Robert L. Grossman, Jody M. Hoyos, Donald J. Johann, Nancy Krunic, Peter Kuhn, Jerry S. H. Lee, Tara Maddala, Marielena Mata, Jeremiah McDole, Omar Perez, Howard Scher, Mark D. Stewart, Seema Singh Bhan, Qu Zhang, Lauren C. Leiman
Publikováno v:
Clinical and Translational Science. 16:5-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28013700cd97e9fc489ae1bd392821eb
https://doi.org/10.1111/cts.13427
https://doi.org/10.1111/cts.13427
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 90K, Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc65e1ac690c49124931e31ae4c177
https://doi.org/10.1158/1078-0432.22452491
https://doi.org/10.1158/1078-0432.22452491
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 79K, GAG-HERV-K ch22q11.23 features. Endogenous retrovirus K from chromosome 22 is located on the q11.23 region, nearby the BCR, ZDHHC8P, IGLL1 and RGL4 genes. HERV-K ch22q11.23 has GAG-PRO, POL and ENV genes flanked by LTR sequences. The GA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0838c6564fc154b416058d804e0969b3
https://doi.org/10.1158/1078-0432.22452512
https://doi.org/10.1158/1078-0432.22452512
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 204K, Alignment of GAG proteins derived from human endogenous retroviruses and respective epitopes recognized by prostate cancer patient sera. A, Detail alignment from several GAG-HERV-K family members and the TI-35 binding site (red) highli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d83187d4b2f5169f2f987e5cdacca9a
https://doi.org/10.1158/1078-0432.22452503.v1
https://doi.org/10.1158/1078-0432.22452503.v1
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
Purpose: Human endogenous retroviruses (HERV) encode 8% of the human genome. While HERVs may play a role in autoimmune and neoplastic disease, no mechanistic association has yet been established. We studied the expression and immunogenicity of a HERV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b21101ce75d0e9fd15608c515e17dc91
https://doi.org/10.1158/1078-0432.c.6522497.v1
https://doi.org/10.1158/1078-0432.c.6522497.v1
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 63K, Correlation between antibodies against GAG-HERV-K and group risk or Gleason score in cancer patients. Prostate cancer patients were split (A) in 3 groups according to Gleason score and classified from group risk 1 to 3 and compared to h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07daad0d6e03029ecd33457dc358bab6
https://doi.org/10.1158/1078-0432.22452497
https://doi.org/10.1158/1078-0432.22452497
Autor:
Sacha Gnjatic, Lloyd J. Old, Gerd Ritter, Elke Jäger, Jonathan Melamed, James P. Allison, Caroline Savage, Victor E. Reuter, Sumit K. Subudhi, Susan Slovin, Peter T. Scardino, Howard Scher, Brett Carver, Yuichi Obata, Toshiaki Ishida, Eiichi Nakayama, Erika Ritter, Megan Holz, Denise Frosina, Achim A. Jungbluth, Bernardo Sgarbi Reis
PDF file 341K, qPCR gene expression analysis of chromosome 22q11.23 region in cancer tissues. Total RNA from cancer tissues was submitted to DNAse treatment and reverse transcriptase reaction for cDNA synthesis. The resulting cDNA was used on qPCR to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74f62af6328b84aaf835500ca2e24c9
https://doi.org/10.1158/1078-0432.22452509
https://doi.org/10.1158/1078-0432.22452509
Autor:
Haley Hieronymus, Rajmohan Murali, Amy Tin, Kamlesh Yadav, Wassim Abida, Henrik Moller, Daniel Berney, Howard Scher, Brett Carver, Peter Scardino, Nikolaus Schultz, Barry Taylor, Andrew Vickers, Jack Cuzick, Charles L Sawyers
Publikováno v:
eLife, Vol 7 (2018)
The level of copy number alteration (CNA), termed CNA burden, in the tumor genome is associated with recurrence of primary prostate cancer. Whether CNA burden is associated with prostate cancer survival or outcomes in other cancers is unknown. We ana
Externí odkaz:
https://doaj.org/article/9bb98e789ff74231b7de3a9771793c64
Autor:
Fanying Tang, Duo Xu, Shangqian Wang, Chen Khuan Wong, Alexander Martinez-Fundichely, Cindy Lee, Sandra Cohen, Jane Park, Corinne Hill, Kenneth Eng, Rohan Bareja, Teng Han, Eric Minwei Liu, Ann Palladino, Wei Di, Dong Gao, Wassim Abida, Shaham Beg, Loredana Puca, Maximiliano Meneses, Elisa De Stanchina, Michael Berger, Anuradha Gopalan, Lukas Dow, Juan Miguel Mosquera, Himisha Beltran, Cora Sternberg, Ping Chi, Howard Scher, Andrea Sboner, Yu Chen, Ekta Khurana
Publikováno v:
Cancer Research. 82:B026-B026
In castration-resistant prostate cancer (CRPC), the loss of androgen receptor (AR) dependence leads to clinically aggressive tumors with few therapeutic options. We used ATAC-seq (assay for transposase-accessible chromatin sequencing), RNA-seq, and D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fc75e60d68175730246f035ff095a6e
https://doi.org/10.1158/1538-7445.cancepi22-b026
https://doi.org/10.1158/1538-7445.cancepi22-b026