Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Howard S. Silverman"'
Autor:
Mark Sutton-Smith, Ann Harris, Michael A. Hollingsworth, Paul Heal, Howard R. Morris, Howard S. Silverman, Kimberley McDermott, Anne Dell, Shih Hsing Leir
Publikováno v:
Glycobiology. 13:265-277
The serine- and threonine-rich tandem repeat (TR) units that make up the characteristic feature of mucin glycoproteins are often polymorphic with substantial genetic variation in TR number. The precise effect of TR number on O-glycosylation is not fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8272ab72fbd613bbdfe732d6610f314
https://doi.org/10.1093/glycob/cwg028
https://doi.org/10.1093/glycob/cwg028
Autor:
Howard R. Morris, Shih Hsing Leir, Paul Heal, Simon Parry, Timea Palmai-Pallag, Anne Dell, Ann Harris, Mark Sutton-Smith, Howard S. Silverman
Publikováno v:
Glycoconjugate Journal. 19:379-384
The O-glycans that decorate mucin glycoproteins contribute to the biophysical and biochemical properties of these molecules and hence their function as a barrier and lubricant on epithelial surfaces. Alterations in mucin O-glycosylation in certain di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a922fd76309baf426bc8b085634ef1f8
https://doi.org/10.1023/b:glyc.0000004009.24191.d3
https://doi.org/10.1023/b:glyc.0000004009.24191.d3
Autor:
Simon Parry, Colm J. Reid, Anne Dell, Michael A. Hollingsworth, Mark Sutton-Smith, Ann Harris, Howard R. Morris, Kimberly M. McDermott, Michael D. Burdick, Surinder K. Batra, Howard S. Silverman
Publikováno v:
Glycobiology. 11:459-471
The biochemical and biophysical properties of mucins are largely determined by extensive O-glycosylation of serine- and threonine-rich tandem repeat (TR) domains. In a number of human diseases aberrant O-glycosylation is associated with variations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd3e49f135b0c33a940266b99745771
https://doi.org/10.1093/glycob/11.6.459
https://doi.org/10.1093/glycob/11.6.459
Autor:
Calvin C. Wilhide, Howard S. Silverman, Arthur T. Hoang, Ralph H. Hruban, Emily E. Milliken, Rene J. Alvarez, Chi V. Dang, Sanford Gips, Nicanor I. Moldovan, Pascal J. Goldschmidt-Clermont
Publikováno v:
Biochemical and Biophysical Research Communications. 237:372-381
Endothelial cells provide an antithrombotic and anti-inflammatory barrier for the normal vessel wall. Dysfunction of endothelial cells has been shown to promote atherosclerosis, and normalization of previously dysfunctional endothelial cells can inhi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb6aee4879dc6792f55b78c5a1511f02
https://doi.org/10.1006/bbrc.1997.7085
https://doi.org/10.1006/bbrc.1997.7085
Autor:
Antoine Younes, Howard S. Silverman, Jing Sheng Zheng, Michael T. Crow, Lydia O'Neill, Xilin Long, Marvin O. Boluyt, Edward G. Lakatta
Publikováno v:
Circulation Research. 81:176-186
Abstract The 70-kD S6 kinase (p70 S6K ) has been implicated in the regulation of protein synthesis in many cell types and in the angiotensin II–stimulated hypertrophy of cardiac myocytes. Our purpose was to determine whether p70 S6K plays a role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf34b64b9bfe8fce5ab0b076fec048a
https://doi.org/10.1161/01.res.81.2.176
https://doi.org/10.1161/01.res.81.2.176
Publikováno v:
Circulation Research. 80:699-707
Abstract Studies in animal models and humans suggest that myocardium may adapt to chronic or intermittent prolonged episodes of reduced coronary perfusion. Stable maintenance of partial flow reduction is difficult to achieve in experimental models; t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3300402174a24f0295ad252dd5214f1
https://doi.org/10.1161/01.res.80.5.699
https://doi.org/10.1161/01.res.80.5.699
Autor:
Mark C. Haigney, Howard S. Silverman, Gary Gerstenblith, E. Tanglao, Steven P. Schulman, Burton Silver, J. D. Hill, Edward P. Shapiro
Publikováno v:
Circulation. 92:2190-2197
Background Intracellular magnesium ([Mg] i ) plays an important role in the regulation of myocardial metabolism, contractility, and the maintenance of transsarcolemmal and intracellular ionic gradients. An understanding of the role of magnesium in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::797271d6f0522fcb1727ff7621e48628
https://doi.org/10.1161/01.cir.92.8.2190
https://doi.org/10.1161/01.cir.92.8.2190
Autor:
Howard S. Silverman, Michael D. Stern
Publikováno v:
Cardiovascular Research. 28:581-597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa8d0a3a7872421b347b1690aabbd04
https://doi.org/10.1093/cvr/28.5.581
https://doi.org/10.1093/cvr/28.5.581
Autor:
Patrick du Souich, Sanford Gips, Magdi R.I. Soliman, Sen T. Kau, Tracy J. Halterman, Rashid M. Khan, Richard A. Keith, Burton B. Howe, Jack A. Schwartz, Jingru Hu, Denise Hartemann, Esam E. El-Fakahany, Claude Saunier, Jacqueline Y. Donahue, Pamela Ouyang, Thomas Aversano, Howard S. Silverman, My Linh Do, Roy C. Ziegelstein, Hemendra N. Bhargava, George A. Matwyshyn
Publikováno v:
Pharmacology. 47:388-392
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79c7b31c98bd4a3030b0642693dfe32f
https://doi.org/10.1159/000139123
https://doi.org/10.1159/000139123
Autor:
Jingru Hu, Pamela Ouyang, Sanford Gips, Jacqueline Y. Donahue, Tracy J. Halterman, My Linh Do, Claude Saunier, Jack A. Schwartz, Patrick du Souich, Thomas Aversano, Howard S. Silverman, Richard A. Keith, Sen T. Kau, Rashid M. Khan, Esam E. El-Fakahany, Denise Hartemann, Burton B. Howe, Magdi R.I. Soliman, Roy C. Ziegelstein, Hemendra N. Bhargava, George A. Matwyshyn
Publikováno v:
Pharmacology. 47:I-IV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a712acd1db669a0cf3043b28cfedab00
https://doi.org/10.1159/000139115
https://doi.org/10.1159/000139115