Zobrazeno 1 - 10
of 387
pro vyhledávání: '"Howard S Hochster"'
Autor:
Robert H Shoemaker, Reynold A Panettieri, Steven K Libutti, Howard S Hochster, Norman R Watts, Paul T Wingfield, Philipp Starkl, Lisabeth Pimenov, Riem Gawish, Anastasiya Hladik, Sylvia Knapp, Daniel Boring, Jonathan M White, Quentin Lawrence, Jeremy Boone, Jason D Marshall, Rebecca L Matthews, Brian D Cholewa, Jeffrey W Richig, Ben T Chen, David L McCormick, Romana Gugensberger, Sonja Höller, Josef M Penninger, Gerald Wirnsberger
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0271066 (2022)
As ACE2 is the critical SARS-CoV-2 receptor, we hypothesized that aerosol administration of clinical grade soluble human recombinant ACE2 (APN01) will neutralize SARS-CoV-2 in the airways, limit spread of infection in the lung, and mitigate lung dama
Externí odkaz:
https://doaj.org/article/de12786ecde24914a9f12e92f2296a6a
Autor:
Manish A Shah, Zev A Wainberg, Daniel V T Catenacci, Howard S Hochster, James Ford, Pamela Kunz, Fa-Chyi Lee, Howard Kallender, Fabiola Cecchi, Daniel C Rabe, Harold Keer, Anne-Marie Martin, Yuan Liu, Robert Gagnon, Peter Bonate, Li Liu, Tona Gilmer, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0276211 (2022)
[This corrects the article DOI: 10.1371/journal.pone.0054014.].
Externí odkaz:
https://doaj.org/article/59c2c84b825f40d781e74d4c8add9f83
Autor:
Manish A Shah, Zev A Wainberg, Daniel V T Catenacci, Howard S Hochster, James Ford, Pamela Kunz, Fa-Chyi Lee, Howard Kallender, Fabiola Cecchi, Daniel C Rabe, Harold Keer, Anne-Marie Martin, Yuan Liu, Robert Gagnon, Peter Bonate, Li Liu, Tona Gilmer, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0261994 (2021)
[This corrects the article DOI: 10.1371/journal.pone.0054014.].
Externí odkaz:
https://doaj.org/article/3a8c73388258421cbed41f983d337c90
Autor:
Manish A Shah, Zev A Wainberg, Daniel V T Catenacci, Howard S Hochster, James Ford, Pamela Kunz, Fa-Chyi Lee, Howard Kallender, Fabiola Cecchi, Daniel C Rabe, Harold Keer, Anne-Marie Martin, Yuan Liu, Robert Gagnon, Peter Bonate, Li Liu, Tona Gilmer, Donald P Bottaro
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e54014 (2013)
PURPOSE:The receptors for hepatocyte and vascular endothelial cell growth factors (MET and VEGFR2, respectively) are critical oncogenic mediators in gastric adenocarcinoma. The purpose is to examine the safety and efficacy of foretinib, an oral multi
Externí odkaz:
https://doaj.org/article/1a7e33afc4394f02a5eb75f7293b2527
Autor:
E. Gabriela Chiorean, Vincent Picozzi, Chung‐Pin Li, Marc Peeters, Joan Maurel, Jaswinder Singh, Talia Golan, Jean‐Frédéric Blanc, Sonya C. Chapman, Anwar M. Hussain, Erica L. Johnston, Howard S. Hochster
Publikováno v:
Cancer Medicine, Vol 12, Iss 20, Pp 20353-20364 (2023)
Abstract Background Pancreatic ductal adenocarcinomas (PDAC) are characterized by frequent cell cycle pathways aberrations. This study evaluated safety and efficacy of abemaciclib, a cyclin‐dependent kinase 4 and 6 inhibitor, as monotherapy or in c
Externí odkaz:
https://doaj.org/article/361cb4c885cb4edb9ee2ff88993a88f9
Autor:
Ritesh Kumar, Jongmyung Kim, Matthew P. Deek, Mariam F. Eskander, Prateek Gulhati, Haejin In, Timothy Kennedy, Mihir M. Shah, Miral S. Grandhi, Lyudmyla Berim, Kristen R. Spencer, Russell C. Langan, Howard S. Hochster, Patrick M. Boland, Salma K. Jabbour
Publikováno v:
Current Oncology, Vol 30, Iss 7, Pp 6432-6446 (2023)
Oncological outcomes are improving in gastrointestinal cancer with advancements in systemic therapies, and there is notable potential in combining immunotherapy and radiation therapy (RT) to allow for further improvements. Various preclinical and ear
Externí odkaz:
https://doaj.org/article/729b9f4c7e68413787e8c6f05e59d79e
Autor:
Takayuki Yoshino, Julien Taieb, Yasutoshi Kuboki, Per Pfeiffer, Amit Kumar, Howard S. Hochster
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Trifluridine/tipiracil plus bevacizumab (FTD/TPI + BEV) has shown efficacy and tolerability in refractory metastatic colorectal cancer (mCRC). Because randomized controlled trial (RCT) data comparing FTD/TPI + BEV with FTD/TPI are lacking
Externí odkaz:
https://doaj.org/article/96c8a39f041a48ffb9a10c68d06ec9e4
Autor:
Aaron J. Scott, Atrayee Basu Mallick, Efrat Dotan, Steven J. Cohen, Philip J. Gold, Howard S. Hochster, Somasundaram Subramaniam, Afsaneh Barzi, George S. Watts, Patrick J. Blatchford, Wells A. Messersmith
Publikováno v:
Cancer Research Communications. 2:1188-1196
Purpose: Multi-tyrosine kinase inhibitors (TKI) have shown clinical activity in patients with metastatic colorectal cancer. Cabozantinib, a multi-TKI, exhibited potent antitumor activity superior to regorafenib in preclinical colorectal cancer patien
Autor:
Wells A. Messersmith, Patrick J. Blatchford, George S. Watts, Afsaneh Barzi, Somasundaram Subramaniam, Howard S. Hochster, Philip J. Gold, Steven J. Cohen, Efrat Dotan, Atrayee Basu Mallick, Aaron J. Scott
Purpose:Multi-tyrosine kinase inhibitors (TKI) have shown clinical activity in patients with metastatic colorectal cancer. Cabozantinib, a multi-TKI, exhibited potent antitumor activity superior to regorafenib in preclinical colorectal cancer patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404e80a399fbeb31c785d08e0d170fc8
https://doi.org/10.1158/2767-9764.c.6550994.v1
https://doi.org/10.1158/2767-9764.c.6550994.v1
Autor:
Wells A. Messersmith, Patrick J. Blatchford, George S. Watts, Afsaneh Barzi, Somasundaram Subramaniam, Howard S. Hochster, Philip J. Gold, Steven J. Cohen, Efrat Dotan, Atrayee Basu Mallick, Aaron J. Scott
Waterfall plot for maximum treatment response.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8d0d621e6d5e30e12dbc85f1b0fceb
https://doi.org/10.1158/2767-9764.22545644.v1
https://doi.org/10.1158/2767-9764.22545644.v1