Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Howard S, Tranter"'
Publikováno v:
Microbiological Quality Assurance ISBN: 9781351074551
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af0c6189c24a361b03c1eac30e0bf37
https://doi.org/10.1201/9781351074551-15
https://doi.org/10.1201/9781351074551-15
Autor:
David M. Sansom, Sayed K. Goda, K. Ravi Acharya, Julie D. McLeod, Matthew Douglas Baker, Claire N. Manzotti, Anastassios C. Papageorgiou, Howard S. Tranter
Publikováno v:
Journal of Biological Chemistry. 279:1297-1303
The previously determined crystal structure of the superantigen staphylococcal enterotoxin C2 (SEC2) showed binding of a single zinc ion located between the N- and C-terminal domains (Papageorgiou, A. C., Acharya, K. R., Shapiro, R., Passalacqua, E.
Autor:
J. Bradford Kline, Susan M. O'Brien, Delia Gutman, Howard S. Tranter, Carleen M. Collins, K. Ravi Acharya, Anastassios C. Papageorgiou
Publikováno v:
The EMBO Journal. 18:9-21
Streptococcal pyrogenic exotoxin A (SpeA) is a superantigen produced by Streptococcus pyogenes and is associated with severe infections characterized by rash, hypotension, multiorgan failure and a high mortality rate. In this study, an allelic form o
Autor:
Anastassios C. Papageorgiou, Rossalyn D. Brehm, C. P. Quinn, K. R. Acharya, Howard S. Tranter, P. F. Bonventre, D. Beer
Publikováno v:
Protein Science. 5:1737-1741
Toxic shock syndrome toxin-1 (TSST-1) is one of a family of staphylococcal exotoxins recognized as microbial superantigens. The toxin plays a dominant role in the genesis of toxic shock in humans through a massive activation of the immune system. Thi
Autor:
K. R. Acharya, Rossalyn D. Brehm, Demetres D. Leonidas, Anastassios C. Papageorgiou, Howard S. Tranter
Publikováno v:
Journal of Molecular Biology. 260:553-569
The pyrogenic toxin toxic shock syndrome toxin-1 from Staphylococcus aureus is a causative agent of the toxic shock syndrome disease. It belongs to a family of proteins known as superantigens that cross-link major histocompatibility class II molecule
Autor:
E Y Jones, Rossalyn D. Brehm, Edward F. Passalacqua, Howard S. Tranter, David I. Stuart, Karl Harlos, K R Acharya
Publikováno v:
Nature. 367:94-97
Superantigens stimulate T cells bearing particular T-cell receptor V beta sequences, so they are extremely potent polyclonal T-cell mitogens. T-cell activation is preceded by binding of superantigens to class II major histocompatibility complex (MHC)
Autor:
Rossalyn D. Brehm, Howard S. Tranter
Publikováno v:
Natural Toxins. 1:250-254
Staphylococcal enterotoxin E has been purified by a combination of Red-A ligand chromatography and Mono-S (cation – exchange) chromatography. Commencing with 30 litres of fermenter-grown culture the method has been used to purify 17 mg of toxin, gi
Publikováno v:
Journal of Applied Bacteriology. 70:344-350
The growth of Staphylococcus aureus S-6, enterotoxin production and exoprotein formation were always higher in NZ-amine A medium compared with brain heart infusion medium. The formation of exoproteins, including enterotoxin B, per bacterial cell in s
Autor:
Rossalyn D. Brehm, Howard S. Tranter
Publikováno v:
Journal of Applied Bacteriology. 69:109S-122S
Autor:
K. Ravi Acharya, Christian Davrinche, Marie Mandron, Howard S. Tranter, Rossalyn Brehm, Marie Charveron, Marie-Françoise Ariès
Publikováno v:
The Journal of allergy and clinical immunology. 117(5)
Background Immune surveillance against microbes at sites of interface with environment involves immediate recognition of pathogen-associated molecular patterns by dendritic cells (DCs). According to their first-line position, DCs are key parameters f