Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Howard L. West"'
Autor:
Scott N. Gettinger, MD, Rudolf M. Huber, MD, PhD, Dong-Wan Kim, MD, PhD, Lyudmila Bazhenova, MD, Karin Holmskov Hansen, MD, Marcello Tiseo, MD, Corey J. Langer, MD, FACP, Luis G. Paz-Ares Rodríguez, MD, PhD, Howard L. West, MD, Karen L. Reckamp, MD, MS, Glen J. Weiss, MD, Egbert F. Smit, MD, PhD, Maximilian J. Hochmair, MD, Sang-We Kim, MD, PhD, Myung-Ju Ahn, MD, PhD, Edward S. Kim, MD, FACP, Harry J.M. Groen, MD, PhD, Joanna Pye, MS, Yuyin Liu, PhD, Pingkuan Zhang, MD, Florin Vranceanu, MD, PhD, D. Ross Camidge, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 3, Iss 9, Pp 100385- (2022)
Introduction: We report brigatinib long-term efficacy and safety from phase 1/2 and phase 2 (ALTA) trials in ALK–rearrangement positive (ALK+) NSCLC. Methods: The phase 1/2 study evaluated brigatinib 30 to 300 mg/d in patients with advanced maligna
Externí odkaz:
https://doaj.org/article/78d40f5a880944a8b24323de142222e5
Autor:
Pasi A. Jänne, Shuanglian Li, Shu Jin, Veronica Bunn, Jianchang Lin, Steven Zhang, Sylvie Vincent, Danny Nguyen, Ryan D. Gentzler, Tarek Mekhail, Howard L. West, Viola W. Zhu, Lyudmila Bazhenova, Shirish M. Gadgeel, Jyoti D. Patel, Anne S. Tsao, Daniel B. Costa, Zofia Piotrowska, Alexander I. Spira, D. Ross Camidge, Joel W. Neal, Gregory J. Riely
Mobocertinib, an oral epidermal growth factor receptor (EGFR) inhibitor targeting EGFR gene mutations, including exon 20 insertions (EGFRex20ins), in non–small cell lung cancer, was evaluated in a phase I/II dose-escalation/expansion trial (Clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d2bc425d2ed40de9a8898b8fdcd6d6
https://doi.org/10.1158/2159-8290.c.6549404
https://doi.org/10.1158/2159-8290.c.6549404
Autor:
Gilberto, Morgan, Neeraj, Agarwal, Toni K, Choueiri, Don S, Dizon, Erika P, Hamilton, Merry Jennifer, Markham, Mark, Lewis, Tatiana M, Prowell, Hope S, Rugo, Vivek, Subbiah, Howard L, West
Publikováno v:
Cancer discovery. 12(7)
Social media (SoMe) platforms have the ability to strengthen the oncology community, leading to intellectual connections that with time develop into friendships. SoMe has immense potential in all areas of medicine, and SoMe in oncology is proof of th
Autor:
Howard L. West, Vivek Subbiah
Publikováno v:
JAMA oncology. 2(5)
Publikováno v:
Clinical Lung Cancer. 1:294-301
Cancer vaccines targeting non small-cell lung cancer (NSCLC) have been studied for decades; clinical trials, for the most part, have focused on the use of autologous and allogeneic whole-tumor cell vaccines. Recent advances in molecular biology and i
Autor:
Thomas E. Stinchcombe, Howard L West
Publikováno v:
The Lancet. 374:1398-1400
Autor:
Julie A, Garrison, Jeannine S, McCune, Robert B, Livingston, Hannah M, Linden, Julie R, Gralow, Georgiana K, Ellis, Howard L, West
Publikováno v:
Oncology (Williston Park, N.Y.). 17(2)
Paclitaxel-induced myalgias and arthralgias occur in a significant fraction of patients receiving therapy with this taxane, potentially impairing physical function and quality of life. Paclitaxel-induced myalgias and arthralgias are related to indivi
Publikováno v:
Brain research. 556(1)
This study used microdialysis to monitor extracellular levels of 5-HT and its metabolite, 5-hydroxyindole acetic acid (5-HIAA) in the lateral hypothalamus (LH) and hippocampus of freely moving rats that had developed a CTA to a 2.5 mM saccharin solut
Publisher Summary This chapter explores application of microdialysis to the study of motivation and conditioning in freely behaving rats. A primary advantage of in vivo microdialysis is that it can be used to examine neurochemistry in behaving animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3249066001d485a3ac1f61e10ee79c6
https://doi.org/10.1016/b978-0-444-81194-3.50021-6
https://doi.org/10.1016/b978-0-444-81194-3.50021-6
Publikováno v:
Clinical Neuropharmacology. 15:704A-705A
The purpose of this research was to measure conditioned release of neurotransmitters in vivo and to study their role as neuromodulators in neural circuits controlling food intake. 1. Extracellular serotonin (5HT) was measured in the hypothalamus duri