Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Howard L Fields"'
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0231124 (2020)
Reported pain intensity depends not only on stimulus intensity but also on previously experienced pain. A painfully hot temperature applied to the skin evokes a lower subjective pain intensity if immediately preceded by a higher temperature, a phenom
Externí odkaz:
https://doaj.org/article/c60e84ceb6cc4e4385b7e62c2882c076
Autor:
Elyssa B Margolis, Howard L Fields
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159097 (2016)
Increased activity of lateral habenula (LHb) neurons is correlated with aversive states including pain, opioid abstinence, rodent models of depression, and failure to receive a predicted reward. Agonists at the mu opioid receptor (MOR) are among the
Externí odkaz:
https://doaj.org/article/51c70c5dab8f42b6ae9c73f1b05e6fd5
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e42365 (2012)
The canonical two neuron model of opioid reward posits that mu opioid receptor (MOR) activation produces reward by disinhibiting midbrain ventral tegmental area (VTA) dopamine neurons through inhibition of local GABAergic interneurons. Although indir
Externí odkaz:
https://doaj.org/article/7af5fb7680734b54b84c90cbb5d59a6f
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15222 (2010)
Brain regions typically contain intermixed subpopulations of neurons with different connectivity and neurotransmitters. This complicates identification of neuronal phenotypes in electrophysiological experiments without using direct detection of uniqu
Externí odkaz:
https://doaj.org/article/9b8f11c9427f48aaaee2ed718ce78946
Autor:
Johannes W. de Jong, Hui Gong, Stephan Lammel, Ignas Cerniauskas, James R. Peck, Hongbin Yang, Byung Kook Lim, Howard L. Fields
Publikováno v:
Nat Neurosci
Pain decreases the activity of many ventral tegmental area (VTA) dopamine (DA) neurons, yet the underlying neural circuitry connecting nociception and the DA system is not understood. Here we show that a subpopulation of lateral parabrachial (LPB) ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65a35fe0863253b629070a924af6a9c
https://doi.org/10.1038/s41593-021-00903-8
https://doi.org/10.1038/s41593-021-00903-8
Autor:
Sam Eldabe, Ewan D McNicol, Rod S Taylor, Simon Thomson, Jane Shipley, John D. Markman, Howard L. Fields, Eric Buchser, Brian H. Kopell, Nathaniel P. Katz, Gregory J Fiore, Richard B. North, John D. Loeser, Chris Hilker, Robert H. Dworkin, Andrea Trescot, Rahul Singh, Angela Leitner, Turo Nurmikko, Robert van Dongen, Ali R. Rezai, Jennifer S. Gewandter, Lalit Venkatesan, McKenzie C Ferguson, Salim M. Hayek, Roshini Jain, Dennis C. Turk
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text.
Spinal cord stimulation (SCS) is an interventional nonpharmacologic treatment used for chronic pain and other indications. Methods for evaluating the safety and efficacy of SCS have evolved
Spinal cord stimulation (SCS) is an interventional nonpharmacologic treatment used for chronic pain and other indications. Methods for evaluating the safety and efficacy of SCS have evolved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cc523cc8d58e7a28115808b2fd0784
https://doi.org/10.1097/j.pain.0000000000002204
https://doi.org/10.1097/j.pain.0000000000002204
Autor:
Howard L Fields
Publikováno v:
Brain
In perilous and stressful situations, the ability to suppress pain can be critical for survival. The rostral ventromedial medulla contains neurons that robustly inhibit nocioception at the level of the spinal cord through a top-down modulatory pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092b2bcfe4f14ca4bc064a488de3156f
https://pubmed.ncbi.nlm.nih.gov/35598161
https://pubmed.ncbi.nlm.nih.gov/35598161
Autor:
Beth D. Darnall, Howard L. Fields
Publikováno v:
Pain. 163:824-826
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f45f1c35d40e48b8e34595a0b930ab
https://doi.org/10.1097/j.pain.0000000000002443
https://doi.org/10.1097/j.pain.0000000000002443
Autor:
Howard L. Fields, Beth D. Darnall
Publikováno v:
Pain. 163:e689-e690
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31252d64b66d397a754d65f4a7818cdb
https://doi.org/10.1097/j.pain.0000000000002518
https://doi.org/10.1097/j.pain.0000000000002518
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 12, p e0231124 (2020)
PLoS ONE, Vol 15, Iss 12, p e0231124 (2020)
Reported pain intensity depends not only on stimulus intensity but also on previously experienced pain. A painfully hot temperature applied to the skin evokes a lower subjective pain intensity if immediately preceded by a higher temperature, a phenom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea70e2856608b6beb44b4a805eaa3c1
http://europepmc.org/articles/PMC7723268
http://europepmc.org/articles/PMC7723268