Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Howard J. Huang"'
Autor:
Ambalavanan Arunachalam, Fatima Anjum, Justin P. Rosenheck, Reinaldo Rampolla, Reda Girgis, Howard J. Huang, Kathryn Crabtree, Sarah McCormick, Zhiji Zhang, Sangeeta Bhorade, David J. Ross
Publikováno v:
JHLT Open, Vol 6, Iss , Pp 100155- (2024)
Background: Donor-derived cell-free DNA (dd-cfDNA) is a nonspecific plasma biomarker for tissue injury that has been validated for monitoring acute rejection (AR) after lung transplantation (LT). However, no studies to date have focused specifically
Externí odkaz:
https://doaj.org/article/06a2473bbfdf43a6a01e4fa131b8062f
Autor:
Khushboo Goel, Nicholas Egersdorf, Amar Gill, Danting Cao, Scott D. Collum, Soma S. Jyothula, Howard J. Huang, Maor Sauler, Patty J. Lee, Susan Majka, Harry Karmouty-Quintana, Irina Petrache
Publikováno v:
Respiratory Research, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Despite causing increased morbidity and mortality, pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment, due to incomplete understanding of its pathogenesis. Hypertrophy of
Externí odkaz:
https://doaj.org/article/626db4f7648e45edbbbb9656f18e0a7e
Autor:
Ashton A. Connor, MD, PhD, Howard J. Huang, MD, Constance M. Mobley, MD, PhD, Edward A. Graviss, MD, Duc T. Nguyen, MD, PhD, Ahmad Goodarzi, MD, Ashish Saharia, MD, Simon Yau, MD, Mark J. Hobeika, MD, Erik E. Suarez, MD, Mozhgon Moaddab, PharmD, Elizabeth W. Brombosz, PhD, Linda W. Moore, PhD, Stephanie G. Yi, MD, A. Osama Gaber, MD, Rafik Mark Ghobrial, MD, PhD
Publikováno v:
Transplantation Direct, Vol 9, Iss 5, p e1482 (2023)
Background. Combined liver–lung transplantation is an uncommon, although vital, procedure for patients with simultaneous end-stage lung and liver disease. The utility of lung–liver transplant has been questioned because of initial poor survival o
Externí odkaz:
https://doaj.org/article/a42d801093754a2fb0ebbf1b3d8cce55
Autor:
Soma S.K. Jyothula, Andrew Peters, Yafen Liang, Weizhen Bi, Pooja Shivshankar, Simon Yau, Puneet S. Garcha, Xiaoyi Yuan, Bindu Akkanti, Scott Collum, Nancy Wareing, Rajarajan A. Thandavarayan, Fernando Poli de Frias, Ivan O. Rosas, Bihong Zhao, L. Maximilian Buja, Holger K. Eltzschig, Howard J. Huang, Harry Karmouty-Quintana
Publikováno v:
EBioMedicine, Vol 86, Iss , Pp 104351- (2022)
Summary: Background: Coronavirus Disease 2019 (COVID-19) can lead to the development of acute respiratory distress syndrome (ARDS). In some patients with non-resolvable (NR) COVID-19, lung injury can progress rapidly to the point that lung transplant
Externí odkaz:
https://doaj.org/article/fa22655142184804b928d08f4d492c03
Autor:
Zhiyi Liu, Fuyi Liao, Jihong Zhu, Dequan Zhou, Gyu Seong Heo, Hannah P. Leuhmann, Davide Scozzi, Antanisha Parks, Ramsey Hachem, Derek E. Byers, Laneshia K. Tague, Hrishikesh S. Kulkarni, Marlene Cano, Brian W. Wong, Wenjun Li, Howard J. Huang, Alexander S. Krupnick, Daniel Kreisel, Yongjian Liu, Andrew E. Gelman
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Bronchiolitis obliterans syndrome (BOS) is a major impediment to lung transplant survival and is generally resistant to medical therapy. Extracorporeal photophoresis (ECP) is an immunomodulatory therapy that shows promise in stabilizing BOS patients,
Externí odkaz:
https://doaj.org/article/0ccd9c3986a04f8c80494fe161c5497a
Autor:
Cory Wilson, Tinne C.J. Mertens, Pooja Shivshankar, Weizen Bi, Scott D. Collum, Nancy Wareing, Junsuk Ko, Tingting Weng, Ram P. Naikawadi, Paul J. Wolters, Pascal Maire, Soma S.K. Jyothula, Rajarajan A. Thandavarayan, Dewei Ren, Nathan D. Elrod, Eric J. Wagner, Howard J. Huang, Burton F. Dickey, Heide L. Ford, Harry Karmouty-Quintana
Publikováno v:
JCI Insight, Vol 7, Iss 10 (2022)
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with limited treatment options. The role of the developmental transcription factor Sine oculis homeobox homolog 1 (SIX1) in the pathophysiology of lung fibrosis is not known. IPF lung tissue samp
Externí odkaz:
https://doaj.org/article/0b6befeecf974b68b90fc8fc86c89505
Autor:
Stephanie G. Yi, MD, MPH, Linda W. Moore, PhD, Todd Eagar, PhD, Edward A. Graviss, PhD, MPH, FIDSA, Duc T. Nguyen, MD, PhD, Hassan Ibrahim, MD, MS, Howard J. Huang, MD, Mark Hobeika, MD, Robert McMillan, MD, MPH, Ashish Saharia, MD, Constance Mobley, MD, PhD, Hemangshu Podder, MD, PhD, Ashley Drews, MD, R. Mark Ghobrial, MD, PhD, A. Osama Gaber, MD, Richard J. Knight, MD
Publikováno v:
Transplantation Direct, Vol 8, Iss 1, p e1257 (2022)
Background. Data about vaccine efficacy in solid organ transplant patients are limited. We previously reported our initial observation of a 6.2% immunogenicity rate in kidney transplant recipients (KTRs) after administration of 1 dose of the severe a
Externí odkaz:
https://doaj.org/article/d7591da3ccfe4a82a5d4186cf9bdbe02
Autor:
Christine Pham, PharmD, Brett J. Pierce, PharmD, Duc T. Nguyen, MD, PhD, Edward A. Graviss, PhD, MPH, Howard J. Huang, MD
Publikováno v:
Transplantation Direct, Vol 7, Iss 4, p e680 (2021)
Background. Data supporting the use of carfilzomib (CFZ) for treatment of antibody-mediated rejection (AMR) in lung transplantation in combination with plasmapheresis and intravenous immunoglobulin suggest positive outcomes through donor-specific ant
Externí odkaz:
https://doaj.org/article/2916372634f545aba955fe83bb4c3ca3
Autor:
Sunjae Bae, Jennifer L. Alejo, Teresa P.Y. Chiang, William A. Werbel, Aaron A.R. Tobian, Linda W. Moore, Ashrith Guha, Howard J. Huang, Richard J. Knight, A. Osama Gaber, R. Mark Ghobrial, Mara A. McAdams-DeMarco, Dorry L. Segev
Publikováno v:
American Journal of Transplantation. 22:3137-3142
A recent study concluded that SARS-CoV-2 mRNA vaccine responses were improved among transplant patients taking mTOR inhibitors (mTORi). This could have profound implications for vaccine strategies in transplant patients; however, limitations in the s
Autor:
Jennifer L. Alejo, Jonathan Mitchell, Teresa P.-Y. Chiang, Amy Chang, Aura T. Abedon, William A. Werbel, Brian J. Boyarsky, Laura B. Zeiser, Robin K. Avery, Aaron A.R. Tobian, Macey L. Levan, Daniel S. Warren, Allan B. Massie, Linda W. Moore, Ashrith Guha, Howard J. Huang, Richard J. Knight, Ahmed Osama Gaber, Rafik Mark Ghobrial, Jacqueline M. Garonzik-Wang, Dorry L. Segev, Sunjae Bae
Publikováno v:
Transplantation. 106:e452-e460
Solid organ transplant recipients (SOTRs) are less likely to mount an antibody response to SARS-CoV-2 mRNA vaccines. Understanding risk factors for impaired vaccine response can guide strategies for antibody testing and additional vaccine dose recomm