Zobrazeno 1 - 10 of 84 pro vyhledávání: '"Howard J Huang"'
1
Akademický článek
COVID-19 mortality may be reduced among fully vaccinated solid organ transplant recipients.
Autor: Micaela Sandoval, Duc T Nguyen, Howard J Huang, Stephanie G Yi, R Mark Ghobrial, A Osama Gaber, Edward A Graviss
Publikováno v: PLoS ONE, Vol 17, Iss 12, p e0279222 (2022)
BackgroundSolid organ transplant (SOT) recipients are at increased risk for morbidity and mortality from COVID-19 due to their immunosuppressed state and reduced immunogenicity from COVID-19 mRNA vaccines. This investigation examined the association
Externí odkaz: https://doaj.org/article/9751a9d158c0427a946ce86ca51a9093
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2
Akademický článek
Hospitalization and survival of solid organ transplant recipients with coronavirus disease 2019: A propensity matched cohort study.
Autor: Joshua T Swan, Elsie Rizk, Stephen L Jones, Nwabunie Nwana, Juan C Nicolas, Anh Thu Tran, Jiaqiong Xu, Tariq Nisar, Terri Menser, Stephanie G Yi, Linda W Moore, Howard J Huang, R Mark Ghobrial, A Osama Gaber, Richard J Knight
Publikováno v: PLoS ONE, Vol 17, Iss 12, p e0278781 (2022)
BackgroundSolid organ transplant (SOT) recipients are predicted to have worse COVID-19 outcomes due to their compromised immunity. However, this association remains uncertain because published studies have had small sample sizes and variability in ch
Externí odkaz: https://doaj.org/article/897a4dafd5ad4f6a966a09c928a3591a
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3
Akademický článek
The peroxisome proliferator-activated receptor agonist pioglitazone and 5-lipoxygenase inhibitor zileuton have no effect on lung inflammation in healthy volunteers by positron emission tomography in a single-blind placebo-controlled cohort study.
Autor: Delphine L Chen, Howard J Huang, Derek E Byers, Adrian Shifren, Bryan Belikoff, Jacquelyn T Engle, Elizabeth Arentson, Debra Kemp, Sharon Phillips, David E Scherrer, Hideji Fujiwara, Katherine J Spayd, Frank J Brooks, Richard A Pierce, Mario Castro, Warren Isakow
Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0191783 (2018)
BACKGROUND:Anti-inflammatory drug development efforts for lung disease have been hampered in part by the lack of noninvasive inflammation biomarkers and the limited ability of animal models to predict efficacy in humans. We used 18F-fluorodeoxyglucos
Externí odkaz: https://doaj.org/article/eab584034270471c847af99e2a775ed8
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4
Akademický článek
Donor-derived cell-free DNA is a valuable monitoring tool after single lung transplantation: Multicenter analysis
Autor: Ambalavanan Arunachalam, Fatima Anjum, Justin P. Rosenheck, Reinaldo Rampolla, Reda Girgis, Howard J. Huang, Kathryn Crabtree, Sarah McCormick, Zhiji Zhang, Sangeeta Bhorade, David J. Ross
Publikováno v: JHLT Open, Vol 6, Iss , Pp 100155- (2024)
Background: Donor-derived cell-free DNA (dd-cfDNA) is a nonspecific plasma biomarker for tissue injury that has been validated for monitoring acute rejection (AR) after lung transplantation (LT). However, no studies to date have focused specifically
Externí odkaz: https://doaj.org/article/06a2473bbfdf43a6a01e4fa131b8062f
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5
mTOR inhibitors, mycophenolates, and other immunosuppression regimens on antibody response to SARS-CoV-2 mRNA vaccines in solid organ transplant recipients
Autor: Sunjae Bae, Jennifer L. Alejo, Teresa P.Y. Chiang, William A. Werbel, Aaron A.R. Tobian, Linda W. Moore, Ashrith Guha, Howard J. Huang, Richard J. Knight, A. Osama Gaber, R. Mark Ghobrial, Mara A. McAdams-DeMarco, Dorry L. Segev
Publikováno v: American Journal of Transplantation. 22:3137-3142
A recent study concluded that SARS-CoV-2 mRNA vaccine responses were improved among transplant patients taking mTOR inhibitors (mTORi). This could have profound implications for vaccine strategies in transplant patients; however, limitations in the s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d132fd1865271788d0942c0bcd481c02
https://doi.org/10.1111/ajt.17158
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9
Characterization of pulmonary vascular remodeling and MicroRNA-126-targets in COPD-pulmonary hypertension
Autor: Khushboo Goel, Nicholas Egersdorf, Amar Gill, Danting Cao, Scott D. Collum, Soma S. Jyothula, Howard J. Huang, Maor Sauler, Patty J. Lee, Susan Majka, Harry Karmouty-Quintana, Irina Petrache
Publikováno v: Respiratory research. 23(1)
Background Despite causing increased morbidity and mortality, pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD) patients (COPD-PH) lacks treatment, due to incomplete understanding of its pathogenesis. Hypertrophy of pulmonar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4365c4d0e6f4d405561cdf42fa88a283
https://pubmed.ncbi.nlm.nih.gov/36522710
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