Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Howard J Jacob"'
Autor:
R. Tyler McLaughlin, Maansi Asthana, Marc Di Meo, Michele Ceccarelli, Howard J. Jacob, David L. Masica
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-12 (2023)
Abstract Accurately identifying somatic mutations is essential for precision oncology and crucial for calculating tumor-mutational burden (TMB), an important predictor of response to immunotherapy. For tumor-only variant calling (i.e., when the cance
Externí odkaz:
https://doaj.org/article/c5b2cf3cf2c544e188a700aec68c1107
Autor:
Ammar J. Alsheikh, Sabrina Wollenhaupt, Emily A. King, Jonas Reeb, Sujana Ghosh, Lindsay R. Stolzenburg, Saleh Tamim, Jozef Lazar, J. Wade Davis, Howard J. Jacob
Publikováno v:
BMC Medical Genomics, Vol 15, Iss 1, Pp 1-21 (2022)
Abstract Background The remarkable growth of genome-wide association studies (GWAS) has created a critical need to experimentally validate the disease-associated variants, 90% of which involve non-coding variants. Methods To determine how the field i
Externí odkaz:
https://doaj.org/article/d0874d4b110e421f9c22bf448f29db52
Autor:
Tolga Turan, Sarah Kongpachith, Kyle Halliwill, Robert T. McLaughlin, Mikhail Binnewies, Dhemath Reddy, Xi Zhao, Rebecca Mathew, Shiming Ye, Howard J. Jacob, Josue Samayoa
Publikováno v:
Cancer Immunology Research. :OF1-OF15
The development of immune checkpoint–based immunotherapies has been a major advancement in the treatment of cancer, with a subset of patients exhibiting durable clinical responses. A predictive biomarker for immunotherapy response is the preexistin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74eb6f02083acd445f332db699e18d2c
https://doi.org/10.1158/2326-6066.cir-22-0283
https://doi.org/10.1158/2326-6066.cir-22-0283
Autor:
Josue Samayoa, Howard J. Jacob, Shiming Ye, Rebecca Mathew, Xi Zhao, Dhemath Reddy, Mikhail Binnewies, Robert T. McLaughlin, Kyle Halliwill, Sarah Kongpachith, Tolga Turan
Turan et. al Supplementary Methods File S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5289cdd5bb788d8d2e587473a5fbd8bf
https://doi.org/10.1158/2326-6066.22812519.v1
https://doi.org/10.1158/2326-6066.22812519.v1
Autor:
Josue Samayoa, Howard J. Jacob, Shiming Ye, Rebecca Mathew, Xi Zhao, Dhemath Reddy, Mikhail Binnewies, Robert T. McLaughlin, Kyle Halliwill, Sarah Kongpachith, Tolga Turan
Supplementary Figures S1-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfbf87099d4a7eaaa1aa36b3b315f7a
https://doi.org/10.1158/2326-6066.22812522.v1
https://doi.org/10.1158/2326-6066.22812522.v1
Autor:
Josue Samayoa, Howard J. Jacob, Shiming Ye, Rebecca Mathew, Xi Zhao, Dhemath Reddy, Mikhail Binnewies, Robert T. McLaughlin, Kyle Halliwill, Sarah Kongpachith, Tolga Turan
The development of immune checkpoint–based immunotherapies has been a major advancement in the treatment of cancer, with a subset of patients exhibiting durable clinical responses. A predictive biomarker for immunotherapy response is the preexistin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8962b0b2c0742ff7df38360d2f54dbbc
https://doi.org/10.1158/2326-6066.c.6644688.v1
https://doi.org/10.1158/2326-6066.c.6644688.v1
Autor:
Josue Samayoa, Howard J. Jacob, Shiming Ye, Rebecca Mathew, Xi Zhao, Dhemath Reddy, Mikhail Binnewies, Robert T. McLaughlin, Kyle Halliwill, Sarah Kongpachith, Tolga Turan
Supplementary Tables S1-S16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a071892287e20c9a948f5f8f3bdc6a6
https://doi.org/10.1158/2326-6066.22812516
https://doi.org/10.1158/2326-6066.22812516
Autor:
Howard J. Jacob, James D. Shull, Michael B. Dwinell, Peter S. LaViolette, Paula E. North, Jozef Lazar, Zelmira Lazarova, Scott C. Fahrenkrug, Wenfang Tan, Daniel F. Carlson, Jeffery De Pons, Shirng-Wern Tsaih, Sophia Ran, Carol Moreno, Aron M. Geurts, Angela Lemke, Ishan Roy, Stephanie Santarriaga, Allison B. Sarkis, Nathan Rudemiller, Bradley T. Endres, Michael J. Flister
Expanded Materials and Methods, Supplemental Figures, and Supplemental Tables Figure S1. Flow cytometric analysis of peripheral blood from SS, SS.BN3, SSIL2Rγ, and SS.BN3IL2Rγ rats. Figure S2.SH2B3 specifically marks CD31+ blood vessels, but not LY
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c154ffd6a88cb5cd68a80a135811e4
https://doi.org/10.1158/0008-5472.22401336
https://doi.org/10.1158/0008-5472.22401336
Autor:
Howard J. Jacob, James D. Shull, Michael B. Dwinell, Peter S. LaViolette, Paula E. North, Jozef Lazar, Zelmira Lazarova, Scott C. Fahrenkrug, Wenfang Tan, Daniel F. Carlson, Jeffery De Pons, Shirng-Wern Tsaih, Sophia Ran, Carol Moreno, Aron M. Geurts, Angela Lemke, Ishan Roy, Stephanie Santarriaga, Allison B. Sarkis, Nathan Rudemiller, Bradley T. Endres, Michael J. Flister
The majority of causative variants in familial breast cancer remain unknown. Of the known risk variants, most are tumor cell autonomous, and little attention has been paid yet to germline variants that may affect the tumor microenvironment. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0154732934a5924ba7a91c179c2905
https://doi.org/10.1158/0008-5472.c.6505833
https://doi.org/10.1158/0008-5472.c.6505833
Autor:
Nizar Smaoui, Rahul Mehta, Tsing Cheng, Stephanie Manson Brown, Howard J. Jacob, Jeffrey F. Waring, Bridget Riley-Gillis, Mengzhen Liu, Ali Abbasi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::008df08e337be2ea32e1d4d11b83e45d
https://doi.org/10.26226/m.62fa009023ef91001a663bbd
https://doi.org/10.26226/m.62fa009023ef91001a663bbd