Zobrazeno 1 - 10
of 484
pro vyhledávání: '"Howard J, Rosen"'
Autor:
Noah G. Cryns, Emily G. Hardy, Ashlin R. K. Roy, Samir Datta, Andrzej Sokolowski, Virginia E. Sturm, Joel H. Kramer, Adam L. Boxer, Bruce L. Miller, Howard J. Rosen, David C. Perry
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Reward processing involves evaluation of stimuli to inform what an individual works to pursue or avoid. Patients with behavioral variant frontotemporal dementia (bvFTD) often display reward processing changes, including insensitivity to aversive stim
Externí odkaz:
https://doaj.org/article/84740ab73241437f8f11ffd90730fbf6
Autor:
Elisa dePaula França Resende, Vivian P. Lara, Ana Luisa C. Santiago, Clarisse V. Friedlaender, Howard J. Rosen, Jesse A. Brown, Yann Cobigo, Lênio L. G. Silva, Leonardo Cruz de Souza, Luciana Rincon, Lea T. Grinberg, Francisca I. P. Maciel, Paulo Caramelli
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION The influence of hippocampal connectivity on memory performance is well established in individuals with high educational attainment. However, the role of hippocampal connectivity in illiterate populations remains poorly understo
Externí odkaz:
https://doaj.org/article/00ef29b25e9c425090fdc4aa429530c5
Autor:
Stefanie D. Pina‐Escudero, Renaud La Joie, Salvatore Spina, Ji‐Hye Hwang, Zachary A. Miller, Eric J. Huang, Harli Grant, Nidhi S. Mundada, Adam L. Boxer, Maria Luisa Gorno‐Tempini, Howard J. Rosen, Joel H. Kramer, Bruce L. Miller, William W. Seeley, Gil D. Rabinovici, Lea Tenenholz Grinberg
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION Alzheimer's disease (AD) neuropathological changes present with amnestic and nonamnestic (atypical) syndromes. The contribution of comorbid neuropathology as a substratum of atypical expression of AD remains under investigated.
Externí odkaz:
https://doaj.org/article/3a35a738074541e6ac5d67e4c35f4e1e
Autor:
Emily W Paolillo, Kaitlin B Casaletto, Annie L Clark, Jack C Taylor, Hilary W Heuer, Amy B Wise, Sreya Dhanam, Mark Sanderson-Cimino, Rowan Saloner, Joel H Kramer, John Kornak, Walter Kremers, Leah Forsberg, Brian Appleby, Ece Bayram, Andrea Bozoki, Danielle Brushaber, R Ryan Darby, Gregory S Day, Bradford C Dickerson, Kimiko Domoto-Reilly, Fanny Elahi, Julie A Fields, Nupur Ghoshal, Neill Graff-Radford, Matthew G H Hall, Lawrence S Honig, Edward D Huey, Maria I Lapid, Irene Litvan, Ian R Mackenzie, Joseph C Masdeu, Mario F Mendez, Carly Mester, Toji Miyagawa, Georges Naasan, Belen Pascual, Peter Pressman, Eliana Marisa Ramos, Katherine P Rankin, Jessica Rexach, Julio C Rojas, Lawren VandeVrede, Bonnie Wong, Zbigniew K Wszolek, Bradley F Boeve, Howard J Rosen, Adam L Boxer, Adam M Staffaroni
Publikováno v:
JMIR Aging, Vol 7, p e52831 (2024)
BackgroundFrontotemporal lobar degeneration (FTLD) is a leading cause of dementia in individuals aged
Externí odkaz:
https://doaj.org/article/e3a85b9c842b435281a2a70b74fac8bf
Autor:
Daniel W. Sirkis, Caroline Warly Solsberg, Taylor P. Johnson, Luke W. Bonham, Virginia E. Sturm, Suzee E. Lee, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, Bruce L. Miller, Ethan G. Geier, Jennifer S. Yokoyama
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-22 (2023)
Abstract Background Emerging evidence from mouse models is beginning to elucidate the brain’s immune response to tau pathology, but little is known about the nature of this response in humans. In addition, it remains unclear to what extent tau path
Externí odkaz:
https://doaj.org/article/593d8cbdd12d4eee9bf2368860ac1c9f
Autor:
Ashlin R. K. Roy, Fate Noohi, Nathaniel A. Morris, Peter Ljubenkov, Hilary Heuer, Jamie Fong, Matthew Hall, Argentina Lario Lago, Katherine P. Rankin, Bruce L. Miller, Adam L. Boxer, Howard J. Rosen, William W. Seeley, David C. Perry, Jennifer S. Yokoyama, Suzee E. Lee, Virginia E. Sturm
Publikováno v:
NeuroImage: Clinical, Vol 43, Iss , Pp 103649- (2024)
Diminished basal parasympathetic nervous system activity is a feature of frontotemporal dementia that relates to left frontoinsula dysfunction and empathy impairment. Individuals with a pathogenic expansion of the hexanucleotide repeat in chromosome
Externí odkaz:
https://doaj.org/article/3c9d5becbbde4415997ecc5f53eb7962
Autor:
Jack Carson Taylor, Hilary W. Heuer, Annie L. Clark, Amy B. Wise, Masood Manoochehri, Leah Forsberg, Carly Mester, Meghana Rao, Daniell Brushaber, Joel Kramer, Ariane E. Welch, John Kornak, Walter Kremers, Brian Appleby, Bradford C. Dickerson, Kimiko Domoto‐Reilly, Julie A. Fields, Nupur Ghoshal, Neill Graff‐Radford, Murray Grossman, Matthew GH Hall, Edward D. Huey, David Irwin, Maria I. Lapid, Irene Litvan, Ian R. Mackenzie, Joseph C. Masdeu, Mario F. Mendez, Naomi Nevler, Chiadi U. Onyike, Belen Pascual, Peter Pressman, Katherine P. Rankin, Buddhika Ratnasiri, Julio C. Rojas, Maria Carmela Tartaglia, Bonnie Wong, Maria Luisa Gorno‐Tempini, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Adam M. Staffaroni
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 15, Iss 2, Pp n/a-n/a (2023)
Abstract Introduction Remote smartphone assessments of cognition, speech/language, and motor functioning in frontotemporal dementia (FTD) could enable decentralized clinical trials and improve access to research. We studied the feasibility and accept
Externí odkaz:
https://doaj.org/article/ddb1152f42564be09bd4bebba08f13f1
Autor:
Ignacio Illán-Gala, Victor Montal, Sergi Borrego-Écija, Maria Luisa Mandelli, Neus Falgàs, Ariane E. Welch, Jordi Pegueroles, Miguel Santos-Santos, Alexandre Bejanin, Daniel Alcolea, Oriol Dols-Icardo, Olivia Belbin, Mª. Belén Sánchez-Saudinós, Nuria Bargalló, Sofía González-Ortiz, Albert Lladó, Rafael Blesa, Bradford C. Dickerson, Howard J. Rosen, Bruce L. Miller, Alberto Lleó, Maria Luisa Gorno-Tempini, Raquel Sánchez-Valle, Juan Fortea
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2022)
Abstract Background Cortical mean diffusivity is a novel imaging metric sensitive to early changes in neurodegenerative syndromes. Higher cortical mean diffusivity values reflect microstructural disorganization and have been proposed as a sensitive b
Externí odkaz:
https://doaj.org/article/09c1ebfaf4324f0da6843f365e78bb89
Autor:
Alice Y. Hua, Ashlin R.K. Roy, Eena L. Kosik, Nathaniel A. Morris, Tiffany E. Chow, Sladjana Lukic, Maxime Montembeault, Valentina Borghesani, Kyan Younes, Joel H. Kramer, William W. Seeley, David C. Perry, Zachary A. Miller, Howard J. Rosen, Bruce L. Miller, Katherine P. Rankin, Maria Luisa Gorno-Tempini, Virginia E. Sturm
Publikováno v:
NeuroImage: Clinical, Vol 40, Iss , Pp 103522- (2023)
In semantic dementia (SD), asymmetric degeneration of the anterior temporal lobes is associated with loss of semantic knowledge and alterations in socioemotional behavior. There are two clinical variants of SD: semantic variant primary progressive ap
Externí odkaz:
https://doaj.org/article/64dbab23f0cb4dd888d902352223b9d6
Autor:
Kyan Younes, Julio C. Rojas, Amy Wolf, Goh M. Sheng‐Yang, Matteo Paoletti, Gianina Toller, Eduardo Caverzasi, Maria Luisa Mandelli, Ignacio Illán‐Gala, Joel H. Kramer, Yann Cobigo, Bruce L. Miller, Howard J. Rosen, Michael D. Geschwind
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 8, Iss 6, Pp 1183-1199 (2021)
Abstract Objective Identification of brain regions susceptible to quantifiable atrophy in sporadic Creutzfeldt‐Jakob disease (sCJD) should allow for improved understanding of disease pathophysiology and development of structural biomarkers that mig
Externí odkaz:
https://doaj.org/article/65396cfd9bfe4713adc92111c21f418d