Zobrazeno 1 - 10
of 389
pro vyhledávání: '"Howard J, Aizenstein"'
Autor:
Laura Xicota, Lam-Ha T. Dang, Alice Lee, Sharon Krinsky-McHale, Deborah Pang, Lisa Melilli, Sid O'Bryant, Rachel L. Henson, Charles Laymon, Florence Lai, H. Diana Rosas, Beau Ances, Ira Lott, Christy Hom, Bradley Christian, Sigan Hartley, Shahid Zaman, Elizabeth Head, Mark Mapstone, Zhezhen Jin, Wayne Silverman, Nicole Schupf, Benjamin Handen, Joseph H. Lee, Howard J. Aizenstein, Beau M. Ances, Howard F. Andrews, Karen Bell, Rasmus Birn, Adam M. Brickman, Peter Bulova, Amrita Cheema, Kewei Chen, Bradley T. Christian, Isabel Clare, Lorraine Clark, Ann D. Cohen, John N. Constantino, Eric W. Doran, Anne Fagan, Eleanor Feingold, Tatiana M. Foroud, Benjamin L. Handen, Jordan Harp, Sigan L. Hartley, Rachel Henson, Lawrence Honig, Milos D. Ikonomovic, Sterling C. Johnson, Courtney Jordan, M.Ilyas Kamboh, David Keator, William E. Klunk, Julia K. Kofler, William Charles Kreisl, Sharon J. Krinsky-McHale, Patrick Lao, Ira T. Lott, Victoria Lupson, Chester A. Mathis, Davneet Singh Minhas, Neelesh Nadkarni, Sid O’Bryant, Melisa Parisi, Melissa Pettersen, Julie C. Price, Margaret Pulsifer, Michael S. Rafii, Eric Reiman, Batool Rizvi, Laurie Ryan, Frederick Schmitt, Wayne P. Silverman, Dana L. Tudorascu, Rameshwari Tumuluru, Benjamin Tycko, Badri Varadarajan, Desiree A. White, Michael A. Yassa, Fan Zhang
Publikováno v:
EBioMedicine, Vol 110, Iss , Pp 105433- (2024)
Summary: Background: Individuals with Down syndrome (DS) are at high risk of early-onset Alzheimer's disease (AD); yet, some 20 percent do not develop any signs of dementia until after 65 years or in their lifetime. Mosaicism could contribute to this
Externí odkaz:
https://doaj.org/article/7bcbc45f9a5e40b7ab0502504ef1c084
Autor:
Katrina A. Wugalter, Rachel A. Schroeder, Rebecca C. Thurston, Minjie Wu, Howard J. Aizenstein, Ann D. Cohen, M. Ilyas Kamboh, Thomas K. Karikari, Carol A. Derby, Pauline M. Maki
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
BackgroundWomen carrying the APOE4 allele are at greater risk of developing Alzheimer’s disease (AD) from ages 65–75 years compared to men. To better understand the elevated risk conferred by APOE4 carrier status among midlife women, we investiga
Externí odkaz:
https://doaj.org/article/1c84be78ffea4180a58e7ba1605e2a9f
Autor:
Tiago Martins, Bruno de Almeida, Minjie Wu, Kristine A. Wilckens, Davneet Minhas, James W. Ibinson, Howard J. Aizenstein, Tales Santini, Tamer S. Ibrahim
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
The development of innovative non-invasive neuroimaging methods and biomarkers is critical for studying brain disease. Imaging of cerebrospinal fluid (CSF) pulsatility may inform the brain fluid dynamics involved in clearance of cerebral metabolic wa
Externí odkaz:
https://doaj.org/article/46e3323616334c80923cf5a5b08f9948
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-5 (2023)
Abstract Mood symptoms and disorders are common in dementia caregivers, who can be exposed to a myriad of potential stressors including their care recipient’s neuropsychiatric symptoms. Existing evidence indicates that the effects of potentially st
Externí odkaz:
https://doaj.org/article/793e502ecd9b4a55abc161f6beee3abb
Autor:
Akiko Mizuno, Helmet Talib Karim, Maria J. Ly, Brian J. Lopresti, Ann D. Cohen, Areej A. Ali, Chester A. Mathis, William E. Klunk, Howard J. Aizenstein, Beth E. Snitz
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
IntroductionSubjective cognitive decline (SCD) may represent the earliest preclinical stage of Alzheimer's Disease (AD) for some older adults. However, the underlying neurobiology of SCD is not completely understood. Since executive function may be a
Externí odkaz:
https://doaj.org/article/d09dae73482d4c33b4854f3ea1443d5f
Autor:
Joseph Kazan, Andrew R. Gerlach, Akiko Mizuno, Carmen Andreescu, Howard J. Aizenstein, Scott Ward, Kara J. Buente, Sarah T. Stahl
Publikováno v:
Psychiatry Research Communications, Vol 3, Iss 1, Pp 100096- (2023)
This study examined the temporal relationship among depression, anxiety, insomnia, perceived stress, and physical activity in adults aged 60+ years with a history of major depressive disorder. We conducted a longitudinal study with 12 weeks of follow
Externí odkaz:
https://doaj.org/article/d45507160e4e45d582dac58b2da47c24
Autor:
Andrew R. Gerlach, Helmet T. Karim, Joseph Kazan, Howard J. Aizenstein, Robert T. Krafty, Carmen Andreescu
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract Severe worry is a complex transdiagnostic phenotype independently associated with increased morbidity, including cognitive impairment and cardiovascular diseases. We investigated the neurobiological basis of worry in older adults by analyzin
Externí odkaz:
https://doaj.org/article/ea46467a6fbd49629c972560eeb9e94b
Autor:
Charles M. Laymon, Davneet S. Minhas, Sarah K. Royse, Howard J. Aizenstein, Ann D. Cohen, Dana L. Tudorascu, William E. Klunk
Publikováno v:
EJNMMI Physics, Vol 8, Iss 1, Pp 1-16 (2021)
Abstract Purpose Partial-volume correction (PVC) using the Geometric Transfer Matrix (GTM) method is used in positron emission tomography (PET) to compensate for the effects of spatial resolution on quantitation. We evaluate the effect of misspecific
Externí odkaz:
https://doaj.org/article/a1d9e289da664c3c87f10207989a723b
Autor:
Tales Santini, Sossena Wood, Narayanan Krishnamurthy, Tiago Martins, Howard J. Aizenstein, Tamer S. Ibrahim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Recently cleared by the FDA, 7 Tesla (7 T) MRI is a rapidly growing technology that can provide higher resolution and enhanced contrast in human MRI images. However, the increased operational frequency (~ 297 MHz) hinders its full potential
Externí odkaz:
https://doaj.org/article/5166fe25569e4da9a96ad3b96828c606
Autor:
Chemin Lin, Maria Ly, Helmet T. Karim, Wenjing Wei, Beth E. Snitz, William E. Klunk, Howard J. Aizenstein
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-10 (2020)
Abstract Background Pathological processes contributing to Alzheimer’s disease begin decades prior to the onset of clinical symptoms. There is significant variation in cognitive changes in the presence of pathology, functional connectivity may be a
Externí odkaz:
https://doaj.org/article/a3be8f15641945a58a1955808916d54c