Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Howard Holtzer"'
Autor:
H.L. Sweeney, Siegfried Labeit, Howard Holtzer, Ryoichi Matsuda, Z. X. Lin, Marie Louise Bang, S. Holtzer, Koichi Ojima
Publikováno v:
The Journal of Cell Biology
To learn how nebulin functions in the assembly and maintenance of I-Z-I bands, MYC- and GFP- tagged nebulin fragments were expressed in primary cultured skeletal myotubes. Their sites of incorporation were visualized by double staining with anti-MYC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6a194f138c46599ffea651a386eab0e
https://doi.org/10.1083/jcb.150.3.553
https://doi.org/10.1083/jcb.150.3.553
Publikováno v:
Developmental Biology. 199(2):291-308
To explore the roles of specific domains of sarcomeric alpha-actinin (s-alpha-actinin) in the assembly and maintenance of striated myofibrils, myogenic cultures were transfected with four MYC-tagged s-alpha-actinin peptides. They were: (1) full-lengt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ce91d8cc10689206c57cb57b0239df3
Publikováno v:
Cell Motility and the Cytoskeleton. 38:54-74
To understand the multiple roles of alpha-actinin in the assembly of (1) Z bands in muscle, and (2) a variety of cytoskeletal structures in non-muscle cells, 4 sarcomeric alpha-actinin derived cDNAs tagged with a MYC epitope were constructed. The con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b3c1ac9fd0960ff3e673161c7911da5
https://doi.org/10.1002/(sici)1097-0169(1997)38:1<54::aid-cm6>3.0.co
https://doi.org/10.1002/(sici)1097-0169(1997)38:1<54::aid-cm6>3.0.co
Publikováno v:
Proceedings of the National Academy of Sciences. 91:2497-2501
The earliest expression of truncated desmin in transfected PtK2 cells results in the formation of dispersed microprecipitates containing not only the truncated desmin, but also endogenous vimentin and cytokeratin proteins. Desmin microprecipitates wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fd52c6c1cd9a09e384d2ded21dff14
https://doi.org/10.1073/pnas.91.7.2497
https://doi.org/10.1073/pnas.91.7.2497
Autor:
Z X Lin, Camille DiLullo, Howard Holtzer, D. A. Fischman, T. Schultheiss, James J. Choi, L Cohen-Gould
Publikováno v:
Proceedings of the National Academy of Sciences. 89:9282-9286
In many nonmuscle cells, nonsarcomeric alpha-actinin is distributed in the dense bodies of stress fibers, adhesion plaques, and adherens junctions. In striated muscle, a sarcomeric isoform of alpha-actinin (s-alpha-actinin) is found in the Z-bands of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d923ce2d51fd7c965a3e0ca82330294d
https://doi.org/10.1073/pnas.89.19.9282
https://doi.org/10.1073/pnas.89.19.9282
Autor:
S. Holtzer, D. A. Fischman, T. Schultheiss, John M. Murray, Camille DiLullo, Howard Holtzer, James J. Choi, Mei-Hua Lu
Publikováno v:
The Journal of Cell Biology
Experiments are described supporting the proposition that the assembly of stress fibers in non-muscle cells and the assembly of myofibrils in cardiac cells share conserved mechanisms. Double staining with a battery of labeled antibodies against membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2937cd58d5237834775539097e233480
https://doi.org/10.1083/jcb.117.5.1007
https://doi.org/10.1083/jcb.117.5.1007
Autor:
Richard Bischoff, Howard Holtzer
Publikováno v:
The Journal of Cell Biology
The effect of colchicine and other antimitotic drugs was studied in cultures of 11-day chick embryo breast muscle. Exposure of such cultures to 10-6 M colchicine results in fragmentation of the elongate myotubes into rounded, cytoplasmic sacs (myosac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719866c8b619cdb5bb2677537744f495
https://pubmed.ncbi.nlm.nih.gov/19866713
https://pubmed.ncbi.nlm.nih.gov/19866713
Publikováno v:
Molecular and Cellular Biology. 11:4473-4482
Phorbol esters selectively and reversibly disassemble the contractile apparatus of cultured skeletal muscle as well as inhibit the synthesis of many contractile proteins without inhibiting that of housekeeping proteins. We now demonstrate that phorbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58c4e3900703fb9e1f26b3860c0c8391
https://doi.org/10.1128/mcb.11.9.4473-4482.1991
https://doi.org/10.1128/mcb.11.9.4473-4482.1991
Publikováno v:
The Journal of Cell Biology
An expression vector was prepared containing a cDNA coding for a truncated version of the intermediate filament (IF) protein desmin. The encoded truncated desmin protein lacks a portion of the highly conserved alpha-helical rod region as well as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::213523124e1d04c02ff697c828e371ff
http://europepmc.org/articles/PMC2289110
http://europepmc.org/articles/PMC2289110