Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Howard G. Hutchinson"'
Autor:
Luke J. Laffin, Dennis Bruemmer, Michelle Garcia, Danielle M. Brennan, Ellen McErlean, Douglas S. Jacoby, Erin D. Michos, Paul M Ridker, Tracy Y. Wang, Karol E. Watson, Howard G. Hutchinson, Steven E. Nissen
Publikováno v:
Journal of the American College of Cardiology. 81:1-12
Supplements are commonly used by individuals with indications for lipid-lowering therapy, but evidence of their effectiveness to lower low-density lipoprotein cholesterol (LDL-C) is lacking, particularly when compared with statins.The trial objective
Autor:
Santosh K Verma, Joanna Huang, Howard G Hutchinson, Irisdaly Estevez, Kammy Kuang, Shannon L Reynolds, Sebastian Schneeweiss
Publikováno v:
Clinical epidemiology. 14
Santosh K Verma,1,2 Joanna Huang,3 Howard G Hutchinson,4 Irisdaly Estevez,1 Kammy Kuang,1 Shannon L Reynolds,1 Sebastian Schneeweiss1,5 1Science, Aetion, Inc, New York, NY, USA; 2Department of Family Medicine and Community Health, University of Massa
Autor:
Efrain Reisin, Matthew R. Weir, Bonita Falkner, Howard G. Hutchinson, Deborah A. Anzalone, Michael L. Tuck for the Treatment in Obese Patients With Hypertension
Publikováno v:
Hypertension. 30:140-145
Abstract Because obesity-associated hypertension has unique hemodynamic and hormonal profiles, certain classes of antihypertensive agents may be more effective than others as monotherapy. Thus, we compared the efficacy and safety of the angiotensin-c
Publikováno v:
Cardiovascular Research. 35:158-167
Objective: While natriuretic peptides can inhibit growth of vascular smooth muscle cells (VSMC), controversy exists as to whether this effect is mediated via the guanylate cyclase-coupled receptors, NPR-A and NPR-B, or the clearance receptor, NPR-C.
Autor:
Howard G. Hutchinson, Michael B. Fowler, Tomohiro Katsuya, Lars Gullestad, Guy A. Haywood, Masatsugu Horiuchi, Richard E. Pratt
Publikováno v:
Circulation. 95:1201-1206
Background The availability of selective antagonists for angiotensin II receptors has focused interest on the gene expression of angiotensin II–receptor subtypes in the human heart. Methods and Results We analyzed expression of the AT 1 and AT 2 su
Publikováno v:
Cardiovascular research. 41(3)
Objective: To examine the exact profile of expression and to determine the functional significance of the angiotensin II (Ang II), type 1 (AT1) and type 2 (AT2) receptors during rat aortic development and following rat carotid artery balloon injury.
Autor:
Howard G. Hutchinson, Wataru Hayashida, Lunan Zhang, Victor J. Dzau, Masatsugu Horiuchi, Ryuichi Morishita, Masatoshi Nakajima, Masahiko Fujinaga, Richard E. Pratt
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 92(23)
The type 1 angiotensin II (AT1) receptor is well characterized but the type 2 (AT2) receptor remains an enigma. We tested the hypothesis that the AT2 receptor can modulate the growth of vascular smooth muscle cells by transfecting an AT2 receptor exp
Publikováno v:
Tetrahedron. 40:2359-2363
The synthesis and characterizations of 2-bromoporphin, 5-bromoporphin, 5,15-dibromoporphin, and 5, 10, 15-tribromoporphin are described. Yields of the bromoporphins obtained with a variety of brominating agents are reported. Spectral properties were