Výsledky vyhledávání - "Howard F Jenkinson"

Akademický článek

Comparative proteomic study of dog and human saliva.

Autor: Phutsa Sanguansermsri, Howard F Jenkinson, Jitkamol Thanasak, Kongthawat Chairatvit, Sittiruk Roytrakul, Suthathip Kittisenachai, Duangchewan Puengsurin, Rudee Surarit

Publikováno v: PLoS ONE, Vol 13, Iss 12, p e0208317 (2018)

Saliva contains many proteins that have an important role in biological process of the oral cavity and is closely associated with many diseases. Although the dog is a common companion animal, the composition of salivary proteome and its relationship

Externí odkaz: https://doaj.org/article/930ee1e026d74664a39c8e46da4185a2

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Akademický článek

The AgI/II family adhesin AspA is required for respiratory infection by Streptococcus pyogenes.

Autor: Linda Franklin, Angela H Nobbs, Laura Bricio-Moreno, Christopher J Wright, Sarah E Maddocks, Jaspreet Singh Sahota, Joe Ralph, Matthew O'Connor, Howard F Jenkinson, Aras Kadioglu

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e62433 (2013)

Streptococcus pyogenes (GAS) is a human pathogen that causes pharyngitis and invasive diseases such as toxic shock syndrome and sepsis. The upper respiratory tract is the primary reservoir from which GAS can infect new hosts and cause disease. The fa

Externí odkaz: https://doaj.org/article/32b6b3615dd34e3ab1c16d21e70a5254

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Akademický článek

In vivo model for microbial invasion of tooth root dentinal tubules

Autor: Jane L. BRITTAN, Susan V. SPRAGUE, Emma L. MACDONALD, Robert M. LOVE, Howard F. JENKINSON, Nicola X. WEST

Publikováno v: Journal of Applied Oral Science, Vol 24, Iss 2, Pp 126-135 (2016)

ABSTRACT Objective Bacterial penetration of dentinal tubules via exposed dentine can lead to root caries and promote infections of the pulp and root canal system. The aim of this work was to develop a new experimental model for studying bacterial inv

Externí odkaz: https://doaj.org/article/43fb02cd23424dd49c9c7dfb1cdcd62e

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The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture

Autor: Viren V. Patel, Victoria A. Higman, Catherine R. Back, Angela H. Nobbs, Howard F. Jenkinson, Daniel Frankel, Steven G. Burston, Alice E. Parnell, Paul R. Race, Kristian Le Vay, Matthew P. Crump

Publikováno v: Back, C, Higman, V A, Le Vay, K, Patel, V V, Parnell, A E, Frankel, D, Jenkinson, H F, Burston, S G, Crump, M P, Nobbs, A H & Race, P R 2020, ' The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture ', Journal of Biological Chemistry . https://doi.org/10.1074/jbc.RA119.011719
J Biol Chem

The cell surfaces of many bacteria carry filamentous polypeptides termed adhesins that enable binding to both biotic and abiotic surfaces. Surface adherence is facilitated by the exquisite selectivity of the adhesins for their cognate ligands or rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc9c7266182f5b50a383df6f547d704
https://doi.org/10.1074/jbc.ra119.011719

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Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils

Autor: Pyong Woo Park, Akiko Jinno, Atsuko Hayashida, Howard F. Jenkinson

Publikováno v: mBio
mBio, Vol 11, Iss 6 (2020)

Bacterial pathogens have evolved several ingenious mechanisms to subvert host cell biology for their pathogenesis. Bacterial attachment to the host ECM establishes a niche to grow and is considered one of the critical steps of infection. This pathoge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e413f9a8b3e087acd5bcfb7ec4022c
https://doi.org/10.1128/mbio.01907-20

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Interspecies dynamics among bacteria associated with canine periodontal disease

Autor: Rudee Surarit, Angela H. Nobbs, Howard F. Jenkinson, Phutsa Sanguansermsri

Publikováno v: Sanguansermsri, P, Nobbs, A H, Jenkinson, H F & Surarit, R 2018, ' Interspecies dynamics among bacteria associated with canine periodontal disease ', Molecular Oral Microbiology, vol. 33, no. 1, pp. 59-67 . https://doi.org/10.1111/omi.12199

Summary The etiology and pathogenic mechanisms associated with canine periodontal disease are less well understood than the disease in humans. In this study we have reconstructed defined consortia biofilms in vitro of microorganisms identified as pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::868f85a30405f3d0145e17d6b3706bb7
https://doi.org/10.1111/omi.12199

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Oral hygiene as a risk factor in infective endocarditis

Autor: Angela H. Nobbs, Richard G. Mears, Steve W. Kerrigan, Howard F. Jenkinson, Jennifer A Haworth

Publikováno v: Haworth, J A, Mears, R G, Jenkinson, H F, Kerrigan, S W & Nobbs, A H 2017, ' Oral hygiene as a risk factor in infective endocarditis ', Dental Update, vol. 44, no. 9, pp. 877-890 . < https://www.dental-update.co.uk/articleMatchListArticle.asp?aKey=1739 >
University of Bristol-PURE

There are many known associations between oral and systemic diseases. This review paper summarizes the proposed mechanisms underlying the links between dental disease and cardiovascular disease before introducing recent research regarding bacteria-pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f590dfa917f4243db83313a179f808aa
https://doi.org/10.12968/denu.2017.44.9.877

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Mapping the recognition domains of pneumococcal fibronectin-binding proteins PavA and PavB demonstrates a common pattern of molecular interactions with fibronectin type III repeats

Autor: Inga Jensch, Sajida Kanwal, Manfred Rohde, Howard F. Jenkinson, Gottfried J. Palm, Mark Brönstrup, Werner Tegge, Daniela Somplatzki, Sven Hammerschmidt, Thomas P. Kohler

Publikováno v: Molecular Microbiology. 105:839-859

Summary Colonization of mucosal respiratory surfaces is a prerequisite for the human pathobiont Streptococcus pneumoniae (the pneumococcus) to cause severe invasive infections. The arsenal of pneumococcal adhesins interacts with a multitude of extrac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::60a3304406d8f06e42fbf1a78419f6bd
https://doi.org/10.1111/mmi.13740

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The accessory Sec system (SecY2A2) in Streptococcus pneumoniae is involved in export of pneumolysin toxin, adhesion and biofilm formation

Autor: Howard F. Jenkinson, Ariel J. Blocker, Angela H. Nobbs, J. Mark Skehel, Ian Collinson, Mikaila Bandara, Aras Kadioglu

Publikováno v: Jayaweera Bandara, M, Skehel, J M, Kadioglu, A, Collinson, I, Nobbs, A H, Blocker, A J & Jenkinson, H F 2017, ' The accessory Sec system (SecY2A2) in Streptococcus pneumoniae is involved in export of pneumolysin toxin, adhesion and biofilm formation ', Microbes and Infection, vol. 19, pp. 402-412 . https://doi.org/10.1016/j.micinf.2017.04.003
Microbes and Infection

In Streptococcus pneumoniae TIGR4, genes encoding a SecY2A2 accessory Sec system are present within a locus encoding a serine-rich repeat surface protein PsrP. Mutant strains deleted in secA2 or psrP were deficient in biofilm formation, while the Δs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c00a2bccdf145336be7e7b20393f32d
https://doi.org/10.1016/j.micinf.2017.04.003

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