Zobrazeno 1 - 10
of 346
pro vyhledávání: '"Howard F Jenkinson"'
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibit
Externí odkaz:
https://doaj.org/article/28f383a3db294b18b5ef0846687a0eb3
Autor:
Liwen Deng, Brady L Spencer, Joshua A Holmes, Rong Mu, Sara Rego, Thomas A Weston, Yoonsung Hu, Glenda F Sanches, Sunghyun Yoon, Nogi Park, Prescilla E Nagao, Howard F Jenkinson, Justin A Thornton, Keun Seok Seo, Angela H Nobbs, Kelly S Doran
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007848 (2019)
Streptococcus agalactiae (Group B Streptococcus, GBS) normally colonizes healthy adults but can cause invasive disease, such as meningitis, in the newborn. To gain access to the central nervous system, GBS must interact with and penetrate brain or me
Externí odkaz:
https://doaj.org/article/0539ea77d9a54a8db734d9c4912cd18d
Autor:
Jane L. BRITTAN, Susan V. SPRAGUE, Emma L. MACDONALD, Robert M. LOVE, Howard F. JENKINSON, Nicola X. WEST
Publikováno v:
Journal of Applied Oral Science, Vol 24, Iss 2, Pp 126-135 (2016)
ABSTRACT Objective Bacterial penetration of dentinal tubules via exposed dentine can lead to root caries and promote infections of the pulp and root canal system. The aim of this work was to develop a new experimental model for studying bacterial inv
Externí odkaz:
https://doaj.org/article/43fb02cd23424dd49c9c7dfb1cdcd62e
Autor:
Maryta N. Sztukowska, Lindsay C. Dutton, Christopher Delaney, Mark Ramsdale, Gordon Ramage, Howard F. Jenkinson, Angela H. Nobbs, Richard J. Lamont
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT The pleiomorphic yeast Candida albicans is a significant pathogen in immunocompromised individuals. In the oral cavity, C. albicans is an inhabitant of polymicrobial communities, and interspecies interactions promote hyphal formation and bio
Externí odkaz:
https://doaj.org/article/3b174a1b9ca04901aa06082256bb7c14
Autor:
Phutsa Sanguansermsri, Howard F Jenkinson, Jitkamol Thanasak, Kongthawat Chairatvit, Sittiruk Roytrakul, Suthathip Kittisenachai, Duangchewan Puengsurin, Rudee Surarit
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208317 (2018)
Saliva contains many proteins that have an important role in biological process of the oral cavity and is closely associated with many diseases. Although the dog is a common companion animal, the composition of salivary proteome and its relationship
Externí odkaz:
https://doaj.org/article/930ee1e026d74664a39c8e46da4185a2
Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes
Publikováno v:
FEBS Open Bio, Vol 4, Iss C, Pp 283-289 (2014)
The pathogenic bacteria Streptococcus pyogenes can cause an array of diseases in humans, including moderate infections such as pharyngitis (strep throat) as well as life threatening conditions such as necrotizing fasciitis and puerperal fever. The an
Externí odkaz:
https://doaj.org/article/acee8a504c7a421b94b4e9e72be60737
Autor:
Viren V. Patel, Victoria A. Higman, Catherine R. Back, Angela H. Nobbs, Howard F. Jenkinson, Daniel Frankel, Steven G. Burston, Alice E. Parnell, Paul R. Race, Kristian Le Vay, Matthew P. Crump
Publikováno v:
Back, C, Higman, V A, Le Vay, K, Patel, V V, Parnell, A E, Frankel, D, Jenkinson, H F, Burston, S G, Crump, M P, Nobbs, A H & Race, P R 2020, ' The streptococcal multidomain fibrillar adhesin CshA has an elongated polymeric architecture ', Journal of Biological Chemistry . https://doi.org/10.1074/jbc.RA119.011719
J Biol Chem
J Biol Chem
The cell surfaces of many bacteria carry filamentous polypeptides termed adhesins that enable binding to both biotic and abiotic surfaces. Surface adherence is facilitated by the exquisite selectivity of the adhesins for their cognate ligands or rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc9c7266182f5b50a383df6f547d704
https://doi.org/10.1074/jbc.ra119.011719
https://doi.org/10.1074/jbc.ra119.011719
Autor:
Lindsay C. Dutton, Angela H. Nobbs, Katy Jepson, Mark A. Jepson, M. Margaret Vickerman, Sami Aqeel Alawfi, Carol A. Munro, Richard J. Lamont, Howard F. Jenkinson
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT Candida albicans is a fungus that colonizes oral cavity surfaces, the gut, and the genital tract. Streptococcus gordonii is a ubiquitous oral bacterium that has been shown to form biofilm communities with C. albicans. Formation of dual-speci
Externí odkaz:
https://doaj.org/article/07c4261ac2b84ba6b459a69cc1ff14e4
Publikováno v:
mBio
mBio, Vol 11, Iss 6 (2020)
mBio, Vol 11, Iss 6 (2020)
Bacterial pathogens have evolved several ingenious mechanisms to subvert host cell biology for their pathogenesis. Bacterial attachment to the host ECM establishes a niche to grow and is considered one of the critical steps of infection. This pathoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e413f9a8b3e087acd5bcfb7ec4022c
https://doi.org/10.1128/mbio.01907-20
https://doi.org/10.1128/mbio.01907-20
Autor:
Linda Franklin, Angela H Nobbs, Laura Bricio-Moreno, Christopher J Wright, Sarah E Maddocks, Jaspreet Singh Sahota, Joe Ralph, Matthew O'Connor, Howard F Jenkinson, Aras Kadioglu
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62433 (2013)
Streptococcus pyogenes (GAS) is a human pathogen that causes pharyngitis and invasive diseases such as toxic shock syndrome and sepsis. The upper respiratory tract is the primary reservoir from which GAS can infect new hosts and cause disease. The fa
Externí odkaz:
https://doaj.org/article/32b6b3615dd34e3ab1c16d21e70a5254