Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Howard Elford"'
Autor:
Matthew L. Baer, Anna Josephson, Unsong Oh, Catherine Lubetzki, Savannah D. Benusa, George H. DeVries, Brooke A. Sword, Aysegul Dilsizoglu-Senol, Marc Davenne, Rebecca K. Hartley, Howard Elford, Jeffrey L. Dupree, Suneel K Thummala, Kareem C. Clark, Martha Joslyn
Publikováno v:
Glia. 64:1190-1209
Axonal pathology is a key contributor to long-term disability in multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS), but the mechanisms that underlie axonal pathology in MS remain elusive. Evidence sugg
Autor:
Cuihua Zhang, Howard Elford, Junxi Wu, Hanrui Zhang, Souad Belmadani, Barry J. Potter, Xue Gao, Xiangbin Xu
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 295:H2242-H2249
We hypothesized that neutralization of TNF-α at the time of reperfusion exerts a salubrious role on endothelial function and reduces the production of reactive oxygen species. We employed a mouse model of myocardial ischemia-reperfusion (I/R, 30 min
Autor:
Kareem C, Clark, Anna, Josephson, Savannah D, Benusa, Rebecca K, Hartley, Matthew, Baer, Suneel, Thummala, Martha, Joslyn, Brooke A, Sword, Howard, Elford, Unsong, Oh, Aysegul, Dilsizoglu-Senol, Catherine, Lubetzki, Marc, Davenne, George H, DeVries, Jeffrey L, Dupree
Publikováno v:
Glia. 64(7)
Axonal pathology is a key contributor to long-term disability in multiple sclerosis (MS), an inflammatory demyelinating disease of the central nervous system (CNS), but the mechanisms that underlie axonal pathology in MS remain elusive. Evidence sugg
Publikováno v:
Virology. 234(2):277-290
Oxidative stress activates the NF-kappaB/Rel transcription factors which are involved in the activation of numerous immunoregulatory genes and the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR). In the present study, we examin
Autor:
Julie Litz, Robert Farrer, George H. DeVries, Catherine Papadopoulos, Howard Elford, Jeffrey L. Dupree, Christian Campbell, Janice Paletta
Publikováno v:
The FASEB Journal. 26
Publikováno v:
The Journal of Immunology. 194:123.16-123.16
Mast cells play a central role in allergic reactions through high-affinity IgE receptor (FcεRI)-mediated responses. FcεRI cross-linking on mast cells activates multiple signaling pathways that lead to sustained inflammation through degranulation, p
Publikováno v:
The Journal of Immunology. 192:54.8-54.8
Ribonucleotide reductase is the enzyme responsible for catalyzing the production of deoxynucleotide triphosphates (dNTPs), essential for proper DNA synthesis and cell cycle progression. Inhibitors of ribonucleotide reductase have become attractive th
Publikováno v:
Free Radical Biology and Medicine. 49:S155
Publikováno v:
Journal of Medicinal Chemistry. 22:1218-1221
Several alpha-N-heterocyclic carboxaldehyde thiosemicarbazones and their iron and copper complexes have been tested for their cytotoxicity and inhibiting activity against DNA synthesis under controlled metal conditions. No ligands show cytotoxicity a