Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Howard Dene"'
Publikováno v:
Journal of Hypertension. 21:2077-2084
OBJECTIVE To improve the localization of a blood pressure quantitative trait locus (BP QTL) on rat chromosome (RNO) 1. METHODS Congenic substrains were derived from the progenitor congenic strains S.LEW(D1Mco4X1) and S.LEW(D1Mco4X5) which previously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d39102c95cfd3537543971dfc05fb3b
https://doi.org/10.1097/00004872-200311000-00017
https://doi.org/10.1097/00004872-200311000-00017
Publikováno v:
Journal of the American Society of Nephrology. 14:1175-1187
The Dahl salt-sensitive hypertensive (S) rat develops albuminuria early in life even on a low-salt diet. In contrast, the spontaneously hypertensive rat (SHR) is highly resistant to developing albuminuria despite elevated BP. An F(1) hybrid of S and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e6852b5a936d51dbd00554d1c87d14
https://doi.org/10.1097/01.asn.0000060572.13794.58
https://doi.org/10.1097/01.asn.0000060572.13794.58
Localization of a blood pressure QTL to a 2.4-cM interval on rat chromosome 9 using congenic strains
Publikováno v:
Genomics. 81:210-220
A blood pressure (BP) quantitative trait locus (QTL) was previously found on rat chromosome 9 using Dahl salt-sensitive (S) and Dahl salt-resistant (R) rats. A congenic strain, S.R(chr9), constructed by introgressing an R chromosomal segment into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca14b4df2ba08d27e4f90b0c8160df4f
https://doi.org/10.1016/s0888-7543(03)00003-x
https://doi.org/10.1016/s0888-7543(03)00003-x
Publikováno v:
Physiological Genomics. 1:119-125
Saad, Yasser, Michael R. Garrett, Soon Jin Lee, Howard Dene, and John P. Rapp. Localization of a blood pressure QTL on rat chromosome 1 using Dahl rat congenic strains. Physiol. Genomics 1: 119–125, 1999.—We previously reported that markers on ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14aa573593d5508ab571d25f87b108b4
https://doi.org/10.1152/physiolgenomics.1999.1.3.119
https://doi.org/10.1152/physiolgenomics.1999.1.3.119
Autor:
Howard Dene, Oksana I. Dukhanina, Marie-Thérèse Bihoreau, John P. Rapp, Carl Choi, Barbara Hoebee, Michael R. Garrett, George T. Cicila
Publikováno v:
Mammalian Genome. 9:517-520
Our purposes were to develop an improved linkage map for rat Chromosome 3 and to develop new markers polymorphic between Dahl salt-sensitive (S) and Dahl salt-resistant (R) rats. The linkage mapping panel consisted of three F2 populations totaling 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41b7f39e3626bc752fb67eef8dac600c
https://doi.org/10.1007/s003359900811
https://doi.org/10.1007/s003359900811
Autor:
Roxanne Y. Walder, John P. Rapp, Howard Dene, Oksana I. Dukhanina, Theodore W. Kurtz, George T. Cicila, Michael R. Garrett
Publikováno v:
Mammalian Genome. 8:896-902
11 β-hydroxylase (Cyp11b1) mutations were previously linked to altered steroid biosynthesis and blood pressure in Dahl salt-resistant (R) and Dahl salt-sensitive (S) rats. In the present work, interval mapping identified a putative blood pressure qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7fcbfc586e112efe39a951c71ab2b1
https://doi.org/10.1007/s003359900607
https://doi.org/10.1007/s003359900607
Publikováno v:
Hypertension. 30:199-202
Abstract A quantitative trait locus (QTL) for blood pressure was previously detected by linkage analysis in a region of rat chromosome 2 using segregating populations derived from crosses of the Dahl salt-sensitive (Dahl S) rat with rats of the Wista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378318bbeb875245471bcea0f4e1496b
https://doi.org/10.1161/01.hyp.30.2.199
https://doi.org/10.1161/01.hyp.30.2.199
Publikováno v:
Mammalian Genome. 8:229-235
Our purposes were to develop a linkage map for rat Chromosome (Chr) 10, using chromosome-sorted DNA, and to construct congenic strains to localize blood pressure quantitative trait loci (QTL) on Chr 10 with the map. The linkage mapping panel consiste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e072abf4b44ad66a14e21a58cf4dfd
https://doi.org/10.1007/s003359900399
https://doi.org/10.1007/s003359900399
Publikováno v:
American Journal of Hypertension. 6:330-334
Based on the published cDNA base sequence for the (anonymous) SA gene, a polymerase-chain-reaction (PCR) product from the SA gene was obtained from a Dahl salt-sensitive rat kidney cDNA library. Compared to the published sequence, this product had a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4214af242d59570117d92780d55ad61f
https://doi.org/10.1093/ajh/6.4.330
https://doi.org/10.1093/ajh/6.4.330
Publikováno v:
Clinical and Experimental Hypertension. 15:599-614
Renin alleles in the Dahl salt-hypertension sensitive (S) and Dahl salt-hypertension resistant (R) rats are known to strongly cosegregate with blood pressure. The purpose of this work was to look for structural differences in the S and R renin allele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e4c085d8b9cc353929b836a0dab1cd9
https://doi.org/10.3109/10641969309041632
https://doi.org/10.3109/10641969309041632