Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Howard D. Dewald"'
Publikováno v:
Analytical Chemistry. 94:12490-12499
Proteomic absolute quantitation strategies mainly rely on the use of synthetic stable isotope-labeled peptides or proteins as internal standards, which are highly costly and time-consuming to synthesize. To circumvent this limitation, we recently dev
Publikováno v:
International Journal of Mass Spectrometry. 443:41-45
We recently reported a new quantitation method using mass spectrometry (MS) in combination with electrochemistry (EC, J. Am. Soc. Mass Spectrom., 2019, 30, 685). The strength of this method is that no reference standard or isotope-labeled compound is
Autor:
Manpreet Kaur, Qi Wang, Olivier Mozziconacci, Hao Chen, Pengyi Zhao, Howard D. Dewald, Yong Liu, Yong Ick Kim
Publikováno v:
Analytical chemistry. 92(11)
Accurate quantification is essential in the fields of proteomics, clinical assay, and biomarker discovery. Popular methods for absolute protein quantitation by mass spectrometry (MS) involve the digestion of target protein and employ isotope-labeled
Publikováno v:
ChemPhysChem. 17:1104-1108
A new coupling of electrochemistry with mass spectrometry (MS) using probe electrospray ionization (PESI) is presented. Due to the high salt tolerance of PESI, the detection of electrochemical reaction products in room-temperature ionic liquids (RTIL
Publikováno v:
Journal of the American Society for Mass Spectrometry. 26:1676-1685
Electrochemistry (EC) combined with mass spectrometry (MS) is a powerful tool for elucidation of electrochemical reaction mechanisms. However, direct online analysis of electrochemical reaction in aqueous phase was rarely explored. This paper present
Publikováno v:
TrAC Trends in Analytical Chemistry. 70:20-30
Ambient ionization methods, which can be used to ionize samples directly with no or little preparation under ambient conditions, are a new generation of ionization technologies for mass spectrometry (MS). In this article, we review the coupling of el
Publikováno v:
Journal of the American Society for Mass Spectrometry. 28(6)
Online detection of methanol electro-oxidation reaction products [e.g., formaldehyde (HCHO)] by mass spectrometry (MS) is challenging, owing to the high salt content and extreme pH of the electrolyte solution as well as the difficulty in ionizing the
Publikováno v:
Analytical Chemistry. 84:5737-5743
The combination of electrochemistry (EC) and mass spectrometry (MS) is a powerful analytical tool for studying mechanisms of redox reactions, identification of products and intermediates, and online derivatization/recognition of analytes. This work r
Publikováno v:
Analytical Chemistry. 84:3838-3842
Covalent disulfide bond linkage in a protein represents an important challenge for mass spectrometry (MS)-based top-down protein structure analysis as it reduces the backbone cleavage efficiency for MS/MS dissociation. This study presents a strategy
Autor:
Qingzhou Cui, Howard D. Dewald
Publikováno v:
Microchemical Journal. 86:80-88
Potentiostatic current oscillations were observed during electrodissolution of a helical coiled copper wire electrode in acidic sodium chloride when nitrogen was sparged through the solution. The oscillations were studied as a function of solution pH