Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Howard C.B. Graves"'
Publikováno v:
Journal of Urology. 155:738-742
Purpose: We investigated whether purified prostate specific antigen (PSA), a seminal plasma serine protease of the kallikrein enzyme family, is capable of releasing kinin-like peptides from natural substrate glycoproteins in human seminal vesicle flu
Publikováno v:
Journal of Urology. 149:787-792
We evaluated the usefulness of an ultrasensitive immunoassay for prostate specific antigen (PSA), modified from the standard Yang Pros-Check PSA test and with a biological detection limit for PSA in serum of 0.07 ng./ml., to detect residual prostate
Publikováno v:
Clinical Chemistry. 38:735-742
We describe a modification of the Yang Pros-check radioimmunoassay for prostate-specific antigen (PSA) that increases the analytical sensitivity of the assay approximately threefold (from a working range of 0.3-50 to 0.1-1.2 micrograms/L). It can det
Publikováno v:
Journal of Urology. 144:1516-1522
Two leading commercial immunoassays for prostate specific antigen (the Yang Laboratories polyclonal radioimmunoassay and the Hybritech two-site monoclonal radioimmunometric assay) were compared using independently purified antigen as the calibrator.
Publikováno v:
Aktuelle Urologie. 26:58-60
Autor:
K. Grandbois, Thomas A. Stamey, Fernand Labrie, I. Poppe, H van Halbeek, Howard C.B. Graves, Lihua Huang, A. Bélanger
Publikováno v:
The Prostate. 27(4)
Despite the widely accepted use of prostate specific antigen (PSA) as a marker of prostate cancer, this molecule has not yet been completely characterized. Past studies have well established, however, using both amino acid and cDNA sequencing techniq
Publikováno v:
The Journal of urology. 149(4)
We investigated whether urinary prostate specific antigen (PSA) might be a useful marker to detect locally recurrent tumor after radical prostatectomy. We also investigated whether PSA in the first 1 to 5 cc of voided urine is a more useful indicator
Publikováno v:
The Journal of urology. 144(6)
Previous investigators have reported the identity of prostate specific antigen (PSA) and the semen protein p30, but data to support these claims have not been published. We report here the rapid and continuous purification of PSA using a simple two c
Autor:
Julius Horoszewicz, Robert M. Nakamura, Howard C.B. Graves, Ulf-Håkan Stenman, John H. Rippey, Alain Bélanger, Mark H. Wener, Peter E. Maxim, Joan Howanitz, George G. Klee
Publikováno v:
Cancer. 71:2678-2678
Autor:
Howard C.B. Graves
Publikováno v:
Journal of Immunological Methods. 111:157-166
The binding of IgG to a series of surface-immobilized proteins and synthetic polypeptides with differing isoelectric points was investigated by ELISA. The binding of rabbit IgG to a protein-coated test well surface was found to be highly charge depen