Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Howard C. Dittrich"'
Autor:
Beth A Davison, Christopher Edwards, Rohit Loomba, Stephen A Harrison, Gad Cotter, Naim Alkhouri, Gary G Koch, Howard C Dittrich
Publikováno v:
JGH Open, Vol 5, Iss 7, Pp 740-749 (2021)
Abstract Background and Aim Liver histology changes are the current gold standard for evaluating non‐alcoholic steatohepatitis (NASH), but are limited by their invasiveness and variability for sampling and interpretation. We evaluated noninvasive b
Externí odkaz:
https://doaj.org/article/99c7a75280f541f19b45dc9afb173de6
Autor:
Rickey R. Reinhardt, Thomas J. Povsic, Nahush A. Mokadam, Geoffrey A. Answini, Carl J. Pepine, Jay H. Traverse, Timothy D. Henry, Ronald G. Crystal, Howard C. Dittrich, Todd K. Rosengart, E. Magnus Ohman
Publikováno v:
American Heart Journal. 241:38-49
Background Patients with refractory angina (RA) have poor quality of life and new therapies are needed. XC001 is a novel adenoviral vector expressing multiple isoforms of vascular endothelial growth factor (VEGF) promoting an enhanced local angiogeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2783c559aed7df6bee9707074cd74baa
https://doi.org/10.1016/j.ahj.2021.06.013
https://doi.org/10.1016/j.ahj.2021.06.013
Autor:
B. Davison, Gary G. Koch, Howard C. Dittrich, Gad Cotter, Naim Alkhouri, Stephen A. Harrison, Christopher L. Edwards, Rohit Loomba
Publikováno v:
JGH Open: An Open Access Journal of Gastroenterology and Hepatology
JGH Open, Vol 5, Iss 7, Pp 740-749 (2021)
JGH Open, Vol 5, Iss 7, Pp 740-749 (2021)
Background and Aim Liver histology changes are the current gold standard for evaluating non‐alcoholic steatohepatitis (NASH), but are limited by their invasiveness and variability for sampling and interpretation. We evaluated noninvasive biomarkers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d4d141c6297d66d23cc146e2c40aba
https://doi.org/10.1002/jgh3.12575
https://doi.org/10.1002/jgh3.12575
Autor:
Gary G. Koch, Howard C. Dittrich, Gad Cotter, Beth A. Davison, Jerry R. Colca, Arun J. Sanyal, Julie Iwashita, Christopher L. Edwards, Naim Alkhouri, Stephen A. Harrison
Publikováno v:
Journal of Hepatology. 73:1322-1332
Background & Aims Liver biopsies are a critical component of pivotal studies in non-alcoholic steatohepatitis (NASH), constituting inclusion criteria, risk stratification factors and endpoints. We evaluated the reliability of NASH Clinical Research N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b867a39ace31820225ef357dede0cf4
https://doi.org/10.1016/j.jhep.2020.06.025
https://doi.org/10.1016/j.jhep.2020.06.025
Autor:
Naim Alkhouri, Stephen A. Harrison, Rohit Loomba, Jerry R. Colca, Bo Hyun Lee, Kenneth Cusi, Orville G. Kolterman, Christopher L. Edwards, Gad Cotter, Arun J. Sanyal, Beth A. Davison, Howard C. Dittrich
Publikováno v:
Journal of Hepatology. 72:613-626
Background & Aims MSDC-0602K is a novel insulin sensitizer designed to preferentially target the mitochondrial pyruvate carrier while minimizing direct binding to the transcriptional factor PPARγ. Herein, we aimed to assess the efficacy and safety o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0874f9cd70fe78f27c8bd6c4f02c40
https://doi.org/10.1016/j.jhep.2019.10.023
https://doi.org/10.1016/j.jhep.2019.10.023
Autor:
Keith C. Ferdinand, Stephanie Desbrandes, Henry R. Black, Bruno Besse, Howard C. Dittrich, Shawna D. Nesbitt, Fabrice Balavoine
Publikováno v:
Circulation. 140:138-146
Background: Despite existing therapy, successful control of hypertension in the United States is estimated at less than 50%. In blacks, hypertension occurs earlier, is more severe, controlled less often and has a higher morbidity and mortality than i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9d2f5d9826d04f164ca5294619d36f5
https://doi.org/10.1161/circulationaha.119.040070
https://doi.org/10.1161/circulationaha.119.040070
Publikováno v:
Diabetes. 69
Use of the first-generation insulin sensitizer pioglitazone is limited by PPARγ-driven side effects. MSDC-0602K was designed to maintain pioglitazone’s effects on the mitochondrial pyruvate carrier (MPC), but with minimal direct PPARγ binding. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f630be3319576e3fd2797c39969f8a6
https://doi.org/10.2337/db20-1090-p
https://doi.org/10.2337/db20-1090-p
Autor:
Daniel M. Bloomfield, Biniyam G. Demissei, Marco Metra, Jorge Rubio-Gracia, Gad Cotter, Christopher M. O'Connor, John R. Teerlink, Piotr Ponikowski, Michael M. Givertz, Adriaan A. Voors, Beth A. Davison, Howard C. Dittrich, Kevin Damman, John G.F. Cleland, Juan Ignacio Pérez-Calvo, Jozine M. ter Maaten
Publikováno v:
International Journal of Cardiology, 258, 185-191. ELSEVIER IRELAND LTD
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Background: Congestion is the main reason for hospital admission for acute decompensatecl heart failure (ADHF). A better understanding of the clinical course of congestion and factors associated with decongestion are therefore important. We studied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72058522311d9e70b56d844785ed8f5b
https://doi.org/10.1016/j.ijcard.2018.01.067
https://doi.org/10.1016/j.ijcard.2018.01.067
Autor:
Robert Spiera, John Varga, Jessica K. Gordon, Robert W. Simms, Howard C. Dittrich, Robert Lafyatis, Julio C. Mantero, Nina Kishore, Mary Carns
Publikováno v:
Journal of Investigative Dermatology. 137:2473-2483
Several studies have suggested that Wnts might contribute to skin fibrosis in systemic sclerosis (SSc) by affecting the differentiation of pluripotent dermal cells. We tested C-82, a therapeutic that inhibits canonical Wnt signaling by blocking the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e99cc17f90e27423812b4b880ff46d
https://doi.org/10.1016/j.jid.2017.06.032
https://doi.org/10.1016/j.jid.2017.06.032
Autor:
Marco Metra, Jasper Tromp, Piotr Ponikowski, Dirk J. van Veldhuisen, Daniel M. Bloomfield, Abhinav Sharma, Mohsin A.F. Khan, Michael M. Givertz, John R. Teerlink, Hans L. Hillege, Adriaan A. Voors, Justin A. Ezekowitz, Christopher M. O'Connor, Gad Cotter, Biniyam G. Demissei, John G.F. Cleland, Beth A. Davison, Howard C. Dittrich
Publikováno v:
European Journal of Heart Failure. 19:1310-1320
Aims It is unclear whether distinct pathophysiological processes are present among patients with acute heart failure (AHF), with and without diabetes. Network analysis of biomarkers may identify correlative associations that reflect different pathoph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcc4161a9b1ef860ecf752b03f612dd4
https://doi.org/10.1002/ejhf.912
https://doi.org/10.1002/ejhf.912