Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Howard C Hang"'
Autor:
Steven Klupt, Kyong Tkhe Fam, Xing Zhang, Pavan Kumar Chodisetti, Abeera Mehmood, Tumara Boyd, Danielle Grotjahn, Donghyun Park, Howard C Hang
Publikováno v:
eLife, Vol 13 (2024)
Enterococcus faecium is a microbiota species in humans that can modulate host immunity (Griffin and Hang, 2022), but has also acquired antibiotic resistance and is a major cause of hospital-associated infections (Van Tyne and Gilmore, 2014). Notably,
Externí odkaz:
https://doaj.org/article/1ef7b504447e4790af0e4470aafde8de
Autor:
Byungchul Kim, Yen-Chih Wang, Charles W Hespen, Juliel Espinosa, Jeanne Salje, Kavita J Rangan, Deena A Oren, Jin Young Kang, Virginia A Pedicord, Howard C Hang
Publikováno v:
eLife, Vol 8 (2019)
We discovered that Enterococcus faecium (E. faecium), a ubiquitous commensal bacterium, and its secreted peptidoglycan hydrolase (SagA) were sufficient to enhance intestinal barrier function and pathogen tolerance, but the precise biochemical mechani
Externí odkaz:
https://doaj.org/article/7760d20205274c9ebf91e7ad5f56d583
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract The discovery of defined peptidoglycan metabolites that activate host immunity and their specific receptors has revealed fundamental insights into host–microbe recognition and afforded new opportunities for therapeutic development against
Externí odkaz:
https://doaj.org/article/2da86f47ee2d4a0885b24615df594db8
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004908 (2015)
Cryptococcus neoformans is an opportunistic yeast that kills over 625,000 people yearly through lethal meningitis. Host phagocytes serve as the first line of defense against this pathogen, but fungal engulfment and subsequent intracellular proliferat
Externí odkaz:
https://doaj.org/article/441825e0bd624599a415fb8bd9b6bcc3
Publikováno v:
PLoS Biology, Vol 11, Iss 7, p e1001597 (2013)
Protein S-palmitoylation, a lipid modification mediated by members of the palmitoyltransferase family, serves as an important membrane-targeting mechanism in eukaryotes. Although changes in palmitoyltransferase expression are associated with various
Externí odkaz:
https://doaj.org/article/2e7b302d0f294eb48c33ce6c6c65fa3c
Publikováno v:
Cell Chemical Biology. 30:436-456
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers known as peptidoglycan that dictates bacterial cell morphology and protects against environmental stresses. Regulation of peptidoglycan turnover is therefore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b104b08b3318916a249dd2022fd9b95e
https://doi.org/10.1016/j.chembiol.2022.11.001
https://doi.org/10.1016/j.chembiol.2022.11.001
Autor:
Tandrila Das, Xinglin Yang, Hwayoung Lee, Emma H. Garst, Estefania Valencia, Kartik Chandran, Wonpil Im, Howard C. Hang
Publikováno v:
ACS Chemical Biology. 17:2109-2120
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cdb5bed9db61df6c7baed40aa60b29d
https://doi.org/10.1021/acschembio.2c00176
https://doi.org/10.1021/acschembio.2c00176
Autor:
Xiaohui Zhao, Kathryn R. Stein, Victor Chen, Matthew E. Griffin, Luke L. Lairson, Howard C. Hang
Publikováno v:
Nature Chemical Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd91f244d9fd39b24574f54c31e969e5
https://doi.org/10.1038/s41589-023-01328-z
https://doi.org/10.1038/s41589-023-01328-z
Publikováno v:
Protein Science. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb8f30052b701743e1d06bc573249d31
https://doi.org/10.1002/pro.4618
https://doi.org/10.1002/pro.4618
Publikováno v:
RSC Chemical Biology. 3:1397-1402
Chemoproteomics of bile acid-protein targets reveals a bile salt hydrolase in Enterococcus faecium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d88c96ef3bbb0c6fcc1f4e1281b87210
https://doi.org/10.1039/d2cb00178k
https://doi.org/10.1039/d2cb00178k