Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Howard C, Hang"'
Autor:
Steven Klupt, Kyong Tkhe Fam, Xing Zhang, Pavan Kumar Chodisetti, Abeera Mehmood, Tumara Boyd, Danielle Grotjahn, Donghyun Park, Howard C Hang
Publikováno v:
eLife, Vol 13 (2024)
Enterococcus faecium is a microbiota species in humans that can modulate host immunity (Griffin and Hang, 2022), but has also acquired antibiotic resistance and is a major cause of hospital-associated infections (Van Tyne and Gilmore, 2014). Notably,
Externí odkaz:
https://doaj.org/article/1ef7b504447e4790af0e4470aafde8de
Autor:
Tandrila Das, Howard C. Hang
Publikováno v:
Viruses, Vol 15, Iss 12, p 2329 (2023)
Interferon-induced transmembrane proteins (IFITM1, 2 and 3) are important host antiviral defense factors. They are active against viruses like the influenza A virus (IAV), dengue virus (DENV), Ebola virus (EBOV), Zika virus (ZIKV) and severe acute re
Externí odkaz:
https://doaj.org/article/947c2b42c1ac4daa8cedb03dc2c71d29
Autor:
Matthew E. Griffin, Howard C. Hang
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 31, Iss , Pp 100818- (2022)
The human microbiota acts as a diverse source of molecular cues that influence the development and homeostasis of the immune system. Beyond endogenous roles in the human holobiont, host-microbial interactions also alter outcomes for immune-related di
Externí odkaz:
https://doaj.org/article/c1cbaf1288544a6ba212cb29611a6788
Publikováno v:
Cell Chemical Biology. 30:436-456
The bacterial cell wall is composed of a highly crosslinked matrix of glycopeptide polymers known as peptidoglycan that dictates bacterial cell morphology and protects against environmental stresses. Regulation of peptidoglycan turnover is therefore
Publikováno v:
Open Biology, Vol 11, Iss 3 (2021)
S-palmitoylation is a reversible posttranslational lipid modification of proteins. It controls protein activity, stability, trafficking and protein–protein interactions. Recent global profiling of immune cells and targeted analysis have identified
Externí odkaz:
https://doaj.org/article/5ecd926d2daf4a5481c3d01a82903904
Autor:
Tandrila Das, Xinglin Yang, Hwayoung Lee, Emma H. Garst, Estefania Valencia, Kartik Chandran, Wonpil Im, Howard C. Hang
Publikováno v:
ACS Chemical Biology. 17:2109-2120
Autor:
Xiaohui Zhao, Kathryn R. Stein, Victor Chen, Matthew E. Griffin, Luke L. Lairson, Howard C. Hang
Publikováno v:
Nature Chemical Biology.
Autor:
Byungchul Kim, Yen-Chih Wang, Charles W Hespen, Juliel Espinosa, Jeanne Salje, Kavita J Rangan, Deena A Oren, Jin Young Kang, Virginia A Pedicord, Howard C Hang
Publikováno v:
eLife, Vol 8 (2019)
We discovered that Enterococcus faecium (E. faecium), a ubiquitous commensal bacterium, and its secreted peptidoglycan hydrolase (SagA) were sufficient to enhance intestinal barrier function and pathogen tolerance, but the precise biochemical mechani
Externí odkaz:
https://doaj.org/article/7760d20205274c9ebf91e7ad5f56d583
Publikováno v:
Clinical & Translational Immunology, Vol 8, Iss 12, Pp n/a-n/a (2019)
Abstract The discovery of defined peptidoglycan metabolites that activate host immunity and their specific receptors has revealed fundamental insights into host–microbe recognition and afforded new opportunities for therapeutic development against
Externí odkaz:
https://doaj.org/article/2da86f47ee2d4a0885b24615df594db8
Publikováno v:
Protein Science. 32