Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Howard B. Lassman"'
Autor:
Howard B Lassman, Karon S Simpson, Christopher M Paap, Marshall R Sack, Karen L Schaefer, Michael W. Horton
Publikováno v:
Annals of Pharmacotherapy. 30:724-729
OBJECTIVE: To characterize pentoxifylline (PTF) and metabolite disposition after multiple oral doses given two and three times a day to patients with renal dysfunction. DESIGN: An open-label, randomized, crossover, parallel group design. SETTING: Com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5eac32380509ffb6da2591669273c21
https://doi.org/10.1177/106002809603000702
https://doi.org/10.1177/106002809603000702
Autor:
Patricia Mitchell, Howard B. Lassman, John H. Wilton, James L. Budny, Jerome J. Schentag, Norma Velasquez, Kishore Divan, David E. Nix
Publikováno v:
Journal of Antimicrobial Chemotherapy. 29:51-57
Twenty patients (mean age 52 +/- 12 years, mean weight 75 +/- 15 kg) scheduled for elective myelogram or spinal anaesthesia were enrolled to determine the cerebrospinal fluid (CSF) penetration of a new expanded spectrum cephalosporin antibiotic, cefp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::692198db26bf2da2c5dd73fd9eb2e2fd
https://doi.org/10.1093/jac/29.suppl_a.51
https://doi.org/10.1093/jac/29.suppl_a.51
Publikováno v:
The Journal of Clinical Pharmacology. 30:948-955
The pharmacokinetics, safety, and tolerance of 1,2,3,4-tetrahydro-9-aminoacridin-1-olmaleate (HP 029) a potential therapeutic agent for Alzheimer's disease, were assessed after multiple oral doses in a randomized double-blind, placebo controlled, asc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6d0d4d1420949f1f7bc4ed4a09f857
https://doi.org/10.1002/j.1552-4604.1990.tb03576.x
https://doi.org/10.1002/j.1552-4604.1990.tb03576.x
Publikováno v:
The Journal of antimicrobial chemotherapy. 29
An observer-blind randomized, placebo-controlled, crossover study was conducted in 22 healthy male subjects. They received 2 g cefpirome or placebo intravenously following an overnight fast. One hour later they consumed a single 0.5 g/kg dose of alco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e506ffe80fcff2f355710acc5e7f46a
https://pubmed.ncbi.nlm.nih.gov/1601756
https://pubmed.ncbi.nlm.nih.gov/1601756
Autor:
Daniel E. Aultz, Grover C. Helsley, David Hoffman, Arthur R. McFadden, Howard B. Lassman, Jeffrey C. Wilker
Publikováno v:
Journal of Medicinal Chemistry. 20:66-70
A series of 6,11-dihydrodibenz[b,e]oxepin-2-acetic acids has been evaluated for both antiinflammatory and analgetic activity in the carrageenan paw edema and phenylquinone writhing assays. The requirements for optimal activity in this series appear r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd43d44f1459ad7b0810ad5d1042f13
https://doi.org/10.1021/jm00211a013
https://doi.org/10.1021/jm00211a013
Autor:
Anderson V Brian, Howard B. Lassman, Richard C. Allen, J. C. Wilker, William J. Novick, Marc N. Agnew
Publikováno v:
Journal of Medicinal Chemistry. 19:318-325
An extensive series of carboxyarylindoles has been evaluated for antiinflammatory activity in the carrageenin paw edema assay. The requirements for optimal antiinflammatory activity in this series are relatively specific: a central pyrrole nucleus wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff04d776ec274f0918059680d3b5714
https://doi.org/10.1021/jm00224a023
https://doi.org/10.1021/jm00224a023
Publikováno v:
Drugs. 35:53-64
Roxatidine acetate (HOE 760, TZU 0460) is a new H2-receptor antagonist which is more potent than cimetidine and ranitidine. A randomised, double-blind, placebo-controlled study was conducted in healthy men to determine the effects of multiple oral do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ee8744b40afb83be701bdf16141920
https://doi.org/10.2165/00003495-198800353-00011
https://doi.org/10.2165/00003495-198800353-00011
Publikováno v:
The Journal of Clinical Pharmacology. 28:141-152
This report contains the findings of five studies performed to evaluate the pharmacokinetics of roxithromycin (RU 965), a new macrolide antibiotic. Roxithromycin was given as 150- and 300-mg film-coated tablets. The drug is rapidly absorbed after ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962ea48e6781f3fd9a312419b2ef619c
https://doi.org/10.1002/j.1552-4604.1988.tb05738.x
https://doi.org/10.1002/j.1552-4604.1988.tb05738.x
Publikováno v:
Annals of the New York Academy of Sciences. 146:430-447
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f31f4d407a313f37245a19c00a451be2
https://doi.org/10.1111/j.1749-6632.1968.tb20304.x
https://doi.org/10.1111/j.1749-6632.1968.tb20304.x
Autor:
Richard C. Allen, W. J. Jun. Novick, Marc N. Agnew, Howard B. Lassman, V. B. Anderson, J. C. Wilker
Publikováno v:
Chemischer Informationsdienst. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4610c26573942789414cbb4a30880a3
https://doi.org/10.1002/chin.197628236
https://doi.org/10.1002/chin.197628236