Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Howard B, Gutstein"'
Autor:
Diego de Villalobos, Andres Laserna, Cosmo Fowler, John A. Cuenca, Peyton Martin, Michele Guindani, Wenli Dong, Howard B. Gutstein, Kristen J. Price, Joseph L. Nates
Publikováno v:
Anaesthesiology Intensive Therapy, Vol 53, Iss 3, Pp 223-231 (2021)
Externí odkaz:
https://doaj.org/article/37359329e30345b4a0fff0d228ab020e
Autor:
Luke W Monroe, Jack S Johnson, Howard B Gutstein, John P Lawrence, Keith Lejeune, Ryan C Sullivan, Coty N Jen
Publikováno v:
PLoS ONE, Vol 17, Iss 9, p e0273194 (2022)
Severe viral respiratory diseases, such as SARS-CoV-2, are transmitted through aerosol particles produced by coughing, talking, and breathing. Medical procedures including tracheal intubation, extubation, dental work, and any procedure involving clos
Externí odkaz:
https://doaj.org/article/cdd965b41a484211a57f3581377320a2
Autor:
Stephanie Puig, Howard B. Gutstein
Publikováno v:
Neuroscience. 519:147-161
Autor:
Narbeh Edjiu, Howard B. Gutstein
Publikováno v:
Advanced Anesthesia Review ISBN: 0197584527
Malignant hyperthermia (MH) is a life-threatening autosomal dominant disorder of skeletal muscle. Exaggerated calcium release within skeletal muscle results in a severe hypermetabolic state when susceptible individuals are exposed to volatile inhaled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d9a133f6c09d37ebfc3bc713cfe1173
https://doi.org/10.1093/med/9780197584521.003.0267
https://doi.org/10.1093/med/9780197584521.003.0267
Autor:
Wenli Dong, Diego De Villalobos, John Cuenca, Howard B. Gutstein, Peyton Martin, Andres Laserna, Michele Guindani, Cosmo Fowler, Kristen Price, Joseph L. Nates
Publikováno v:
Anaesthesiology Intensive Therapy, Vol 53, Iss 3, Pp 223-231 (2021)
INTRODUCTION Although humans are capable of enduring critically low levels of oxygen, many hypoxaemic patients die despite aggressive therapies. Mimicking the physiological hyperventilation necessary to survive extreme hypoxic conditions could minimi
Autor:
Howard B. Gutstein, Jun-Li Cao, Oliver M. Schlüter, Yao Q. Wang, Junshi Wang, Sun-hui Xia, Yan Dong, Yanhua H. Huang
Publikováno v:
Pain. 162:1322-1333
Pain experience can change the central processing of nociceptive inputs, resulting in persistent allodynia and hyperalgesia. However, the underlying circuit mechanisms remain underexplored. Here, we focus on pain-induced remodeling of the projection
Autor:
Stephanie Puig, Jeffrey S. Morris, Shelby R Szott, Howard B. Gutstein, Katherine E Barker, Peter T Kann
Publikováno v:
Molecular Pharmacology. 98:487-496
Opioids are some of the most potent analgesics available. However, their effectiveness is limited by the development of analgesic tolerance. Traditionally, tolerance was thought to occur by termination of μ-opioid receptor (MOR) signaling via desens
Autor:
Katherine E. Barker, Jill M. Schumacher, Howard B. Gutstein, Alynn J. Lecznar, Jeffrey S. Morris
Publikováno v:
Journal of neuroscience researchREFERENCES. 100(1)
Opioids are commonly used for the treatment of postoperative and post-traumatic pain; however, their therapeutic effectiveness is limited by undesirable and life-threatening side effects. Researchers have long attempted to develop opioid co-administr
Autor:
Howard B. Gutstein, Heather N. Turner, Michael J. Galko, Chang Ru Tsai, Patrick J. Huang, Roger López-Bellido, Stephanie Puig
Publikováno v:
The Journal of Neuroscience. 39:6012-6030
Mechanical sensitization is one of the most difficult clinical pain problems to treat. However, the molecular and genetic bases of mechanical nociception are unclear. Here we develop a Drosophila model of mechanical nociception to investigate the ion
Autor:
Howard B. Gutstein, Omer Barkai, Luba Eli-Berchoer, Ben Title, Alexander M. Binshtok, Stephanie Puig, Shaya Lev, Ben Katz
Publikováno v:
Pain
Supplemental Digital Content is Available in the Text. Our work reveals that the platelet-derived growth factor-BB, by inhibiting nociceptive M-type potassium channels, acts as a pain-inducing proinflammatory factor that significantly contributes to