Zobrazeno 1 - 10
of 433
pro vyhledávání: '"Howard A Fine"'
Autor:
Wei Jiang, Simona Cazacu, Cunli Xiang, Jean C Zenklusen, Howard A Fine, Michael Berens, Brock Armstrong, Chaya Brodie, Tom Mikkelsen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 3, Pp 235-243 (2008)
FK506 binding protein 5 (FKBP5) belongs to a family of immunophilins named for their ability to bind immunosuppressive drugs, also known as peptidyl-prolyl cis-trans isomerases, and also with chaperones to help protein folding. Using glioma cDNA micr
Externí odkaz:
https://doaj.org/article/c682b8c48fcd424687def1ddd43e27d7
Autor:
Mehmet Baysan, Kevin Woolard, Serdar Bozdag, Gregory Riddick, Svetlana Kotliarova, Margaret C Cam, Galina I Belova, Susie Ahn, Wei Zhang, Hua Song, Jennifer Walling, Holly Stevenson, Paul Meltzer, Howard A Fine
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94045 (2014)
In vitro and in vivo models are widely used in cancer research. Characterizing the similarities and differences between a patient's tumor and corresponding in vitro and in vivo models is important for understanding the potential clinical relevance of
Externí odkaz:
https://doaj.org/article/33dbf0d5a88a4bb2a5dc945fd476d097
Autor:
Ido Nevo, Kevin Woolard, Maggie Cam, Aiguo Li, Joshua D Webster, Yuri Kotliarov, Hong Sug Kim, Susie Ahn, Jennifer Walling, Svetlana Kotliarova, Galina Belova, Hua Song, Rolanda Bailey, Wei Zhang, Howard A Fine
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111783 (2014)
Gliomas are mostly incurable secondary to their diffuse infiltrative nature. Thus, specific therapeutic targeting of invasive glioma cells is an attractive concept. As cells exit the tumor mass and infiltrate brain parenchyma, they closely interact w
Externí odkaz:
https://doaj.org/article/0a9b1fa0bcb5449ebfa04dea309b055a
Autor:
Jennifer Ho, John Ondos, Holly Ning, Sharon Smith, Teri Kreisl, Fabio Iwamoto, Joohee Sul, Lyndon Kim, Kate McNeil, Andra Krauze, Uma Shankavaram, Howard A Fine, Kevin Camphausen
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70745 (2013)
Standard treatment for glioblastoma (GBM) is surgery followed by radiation (RT) and temozolomide (TMZ). While there is variability in survival based on several established prognostic factors, the prognostic utility of other factors such as tumor size
Externí odkaz:
https://doaj.org/article/69828596b33a4444b93260639693074d
Autor:
Serdar Bozdag, Aiguo Li, Gregory Riddick, Yuri Kotliarov, Mehmet Baysan, Fabio M Iwamoto, Margaret C Cam, Svetlana Kotliarova, Howard A Fine
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62982 (2013)
Age is a powerful predictor of survival in glioblastoma multiforme (GBM) yet the biological basis for the difference in clinical outcome is mostly unknown. Discovering genes and pathways that would explain age-specific survival difference could gener
Externí odkaz:
https://doaj.org/article/fd413d4cfa814ca8a9bba9617c604f49
Autor:
Mehmet Baysan, Serdar Bozdag, Margaret C Cam, Svetlana Kotliarova, Susie Ahn, Jennifer Walling, Jonathan K Killian, Holly Stevenson, Paul Meltzer, Howard A Fine
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e47839 (2012)
Glioblastoma Multiforme (GBM) is a tumor with high mortality and no known cure. The dramatic molecular and clinical heterogeneity seen in this tumor has led to attempts to define genetically similar subgroups of GBM with the hope of developing tumor
Externí odkaz:
https://doaj.org/article/8c226d2e2a0b4cb6a92f658a0d2832dd
Autor:
Chibawanye I Ene, Lincoln Edwards, Gregory Riddick, Mehmet Baysan, Kevin Woolard, Svetlana Kotliarova, Chen Lai, Galina Belova, Maggie Cam, Jennifer Walling, Ming Zhou, Holly Stevenson, Hong Sug Kim, Keith Killian, Timothy Veenstra, Rolanda Bailey, Hua Song, Wei Zhang, Howard A Fine
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51407 (2012)
Histone methylation regulates normal stem cell fate decisions through a coordinated interplay between histone methyltransferases and demethylases at lineage specific genes. Malignant transformation is associated with aberrant accumulation of repressi
Externí odkaz:
https://doaj.org/article/101956149d3b4e88aa7bbf52ca44aadf
Autor:
Stefan Wuchty, Dolores Arjona, Aiguo Li, Yuri Kotliarov, Jennifer Walling, Susie Ahn, Alice Zhang, Dragan Maric, Rachel Anolik, Jean Claude Zenklusen, Howard A Fine
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14681 (2011)
Despite progress in the determination of miR interactions, their regulatory role in cancer is only beginning to be unraveled. Utilizing gene expression data from 27 glioblastoma samples we found that the mere knowledge of physical interactions betwee
Externí odkaz:
https://doaj.org/article/1aaee877f2a042f0adda14606cd1ed06
Autor:
Frank B. Furnari, Corina Anastasaki, Shan Bian, Howard A. Fine, Tomoyuki Koga, Lu Q. Le, Fausto J. Rodriguez, David H. Gutmann
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 2 (2024)
Externí odkaz:
https://doaj.org/article/ce1de40fcd154f57adc3a04a5aab3822
Autor:
Sean S. Mahase, Michelle Roytman, Diana Roth O'Brien, Jana Ivanidze, Theodore H. Schwartz, Susan C. Pannullo, Rohan Ramakrishna, Rajiv S. Magge, Nicholas Williams, Howard A. Fine, Gloria Chia‐Yi Chiang, Jonathan P. S. Knisely
Publikováno v:
Cancer Reports, Vol 6, Iss 7, Pp n/a-n/a (2023)
Abstract Background Clinical trials evaluating immune checkpoint inhibition (ICI) in recurrent high‐grade gliomas (rHGG) report 7%–20% 6‐month progression‐free survival (PFS), while re‐irradiation demonstrates 28%–39% 6‐month PFS. Aims
Externí odkaz:
https://doaj.org/article/f68f477da7f84ce68a99057c715f8650