The Late Osteoblast/Preosteocyte Cell Line MLO-A5 Displays Mesenchymal Lineage Plasticity In Vitro and In Vivo

Autor: Dongqing Yang, Stan Gronthos, Sandra Isenmann, Howard A. Morris, Gerald J. Atkins

Publikováno v: Stem Cells International, Vol 2019 (2019)

The process of osteoblast switching to alternative mesenchymal phenotypes is incompletely understood. In this study, we tested the ability of the osteoblast/preosteocyte osteogenic cell line, MLO-A5, to also differentiate into either adipocytes or ch

Externí odkaz: https://doaj.org/article/e4d7e2eb1aff4d37a3b1abca0e7a3e13

A Multicenter Study to Evaluate Harmonization of Assays for C-Terminal Telopeptides of Type I Collagen (ß-CTX): A Report from the IFCC-IOF Committee for Bone Metabolism (C-BM)

Autor: Niklas Rye Jørgensen, Hans Pottel, Richard Eastell, John A. Kanis, Etienne Cavalier, Howard A. Morris, Samuel Vasikaran, Konstantinos Makris, Symeon Tournis, Cyrus Cooper

Publikováno v: Cavalier, E, Eastell, R, Jørgensen, N R, Makris, K, Tournis, S, Vasikaran, S, Kanis, J A, Cooper, C, Pottel, H, Morris, H A & on behalf of the IFCC-IOF Committee for Bone Metabolism (C-BM) 2021, ' A Multicenter Study to Evaluate Harmonization of Assays for C-Terminal Telopeptides of Type I Collagen (ß-CTX) : A Report from the IFCC-IOF Committee for Bone Metabolism (C-BM) ', Calcified Tissue International, vol. 108, pp. 785–797 . https://doi.org/10.1007/s00223-021-00816-5
Calcified Tissue International

Background Biochemical bone turnover markers are useful tools to assess bone remodeling. C-terminal telopeptide of type I collagen (ß-CTX) has been recommended as a reference marker for bone resorption in research studies. Methods We describe the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c575375825fbc33936a4ec445794e3
https://doi.org/10.1007/s00223-021-00816-5

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate.

Autor: Elizabeth Stansell, Maria Panico, Kevin Canis, Poh-Choo Pang, Laura Bouché, Daniel Binet, Michael-John O'Connor, Elena Chertova, Julian Bess, Jeffrey D Lifson, Stuart M Haslam, Howard R Morris, Ronald C Desrosiers, Anne Dell

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0124784 (2015)

As HIV-1-encoded envelope protein traverses the secretory pathway, it may be modified with N- and O-linked carbohydrate. When the gp120s of HIV-1 NL4-3, HIV-1 YU2, HIV-1 Bal, HIV-1 JRFL, and HIV-1 JRCSF were expressed as secreted proteins, the threon

Externí odkaz: https://doaj.org/article/27d7d92696914ff1a11ff3d9a4512bc0

Mammary-specific ablation of Cyp24a1 inhibits development, reduces proliferation and increases sensitivity to vitamin D

Autor: Andrew G. Turner, Richard Kremer, David F. Callen, Gerard A. Tarulli, Lei Sheng, Paul H. Anderson, Kate R. Barratt, Howard A. Morris

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 189:240-247

Active vitamin D (1,25(OH)2D) has been shown to regulate numerous cell processes in mammary cells. Degradation of 1,25(OH)2D is initiated by the mitochondrial enzyme, 25-hydroxyvitamin D 24-hydroxylase (CYP24 A1), and provides local control of 1,25(O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c164a6a76dc1934da2e0b940fa9e718f
https://doi.org/10.1016/j.jsbmb.2019.01.005

Characterization of recombinant human plasma lecithin: cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties

Autor: Andras G. Lacko, Andrew J. Reason, Colin Nuckolls, Bhalchandra J. Kudchodkar, Maya P. Nair, Geetha Sundarrajan, P. Haydn Pritchard, Howard R. Morris, Anne Dell

Publikováno v: Journal of Lipid Research, Vol 39, Iss 4, Pp 807-820 (1998)

The major N-linked carbohydrate structures were determined for recombinant human plasma lecithin:cholesterol acyltransferase (LCAT). The analysis of the structure of oligosaccharides by fast atom bombardment mass spectrometry (FAB-MS) and linkage ana

Externí odkaz: https://doaj.org/article/849096fa55c649258b347e7472ca726e