The characterisation of the uptake of microparticulates across intestinal lymphoid tissue

Autor: Howard, Kenneth Alan

Poly(lactide-co-glycolide) (PLG) biodegradable microparticles were evaluated as an oral delivery system for immunisation against equine influenza virus. Model particulates (fluorescent polystyrene and gold labelled polystyrene) were used to character

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.523886

Polycation-based nanoparticle delivery of RNAi therapeutics: Adverse effects and solutions

Autor: Ballarín-González, Borja, Howard, Kenneth Alan

Publikováno v: In Advanced Drug Delivery Reviews December 2012 64(15):1717-1729

Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications

Autor: Ebbesen, Morten Frendø, Kaspersen, Liselotte, Hansen, Irene M, Thomsen, Troels Kragsig, Bienk, Konrad, Cai, Yunpeng, Malle, Birgitte Mølholm, Howard, Kenneth Alan

Publikováno v: Ebbesen, M F, Ebbesen, M F, Kaspersen, L, Hansen, I M, Thomsen, T K, Bienk, K, Cai, Y, Malle, B M & Howard, K A 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications. ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359-2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236
Hansen, I, Ebbesen, M F, Kaspersen, L, Thomsen, T B, Bienk, K, Cai, Y, Malle, B M & Howard, K 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359–2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236

This study investigates the effects of different molecular weight hyaluronic acids (HAs) on the mucosal nanostructure using a pig stomach mucin hydrogel as a mucosal barrier model. Microparticles (1.0 μm) and nanoparticles (200 nm) were used as prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331021d356aa2be8cd9a3637ee9555bd
https://doi.org/10.1021/acs.molpharmaceut.7b00236

Modified payload molecules and their interactions and uses

Autor: Howard, Kenneth Alan, Kragh-Hansen, Ulrich, Bienk, Konrad

Publikováno v: Howard, K A, Kragh-Hansen, U & Bienk, K, Modified payload molecules and their interactions and uses, Patentnummer PCT/DK2013/050223, IPC nr. WO2014005596 A1 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pure_au_____::ab6dc312b14a5e24466d493089fb2eb5
https://pure.au.dk/portal/da/publications/modified-payload-molecules-and-their-interactions-and-uses(3175c99b-9ae5-4d93-b38b-9c3409d109e1).html

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